| dbo:abstract |
Talipexole (B-HT920, Domnin) is a dopamine agonist that is marketed as a treatment for Parkinson's Disease in Japan by Boehringer Ingelheim; it was introduced in 1996. As of December 2014 it was not approved for marketing in the US nor in Europe. Talipexole is a D2 dopamine receptor agonist and interacts both pre- and post-synaptic receptors. It also is an α2-adrenergic agonist. The main side effects are drowsiness, dizziness, hallucinations and minor gastrointestinal complaints. In 2008 the Japanese Ministry of Health, Labour, and Welfare mandated that Boehringer add a warning to the label concerning the risk of sudden onset of sleep. (en) |
| dbo:alternativeName |
Domin (en) |
| dbo:casNumber |
101626-70-4 36085-73-1 |
| dbo:chEMBL |
1289023 |
| dbo:fdaUniiCode |
7AM2J46Z1Y 9R6E1D8H1O |
| dbo:pubchem |
5374 |
| dbo:thumbnail |
wiki-commons:Special:FilePath/Talipexole.svg?width=300 |
| dbo:wikiPageExternalLink |
https://pubchem.ncbi.nlm.nih.gov/compound/134342 |
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| dbp:atcPrefix |
none (en) |
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10 (xsd:integer) |
| dbp:casNumber |
101626 (xsd:integer) 36085-73-1 (en) |
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| dbp:chemspiderid |
5181 (xsd:integer) |
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15 (xsd:integer) |
| dbp:image |
Talipexole-3D-balls.png (en) |
| dbp:index2Label |
DIHYDROCHLORIDE (en) |
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6 (xsd:integer) |
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5442 (xsd:integer) |
| dbp:legalStatus |
Rx-only (en) |
| dbp:n |
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5374 (xsd:integer) |
| dbp:routesOfAdministration |
Oral (en) |
| dbp:s |
1 (xsd:integer) |
| dbp:smiles |
C=CCN1CCC2=CSCN (en) n1c2cCCNC\C=C (en) |
| dbp:stdinchi |
1 (xsd:integer) |
| dbp:stdinchikey |
DHSSDEDRBUKTQY-UHFFFAOYSA-N (en) |
| dbp:synonyms |
Alefexole (en) |
| dbp:tradename |
Domin (en) |
| dbp:unii |
7 (xsd:integer) 9 (xsd:integer) |
| dbp:verifiedfields |
changed (en) |
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changed (en) |
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| dcterms:subject |
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| gold:hypernym |
dbr:Agonist |
| rdf:type |
owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 yago:WikicatMolecularFormulas yago:Abstraction100002137 yago:AliphaticCompound114601294 yago:Alkene114713120 yago:Chemical114806838 yago:Communication100033020 yago:Compound114818238 yago:Formula106816935 yago:Material114580897 yago:Matter100020827 yago:Message106598915 yago:MolecularFormula106817173 yago:OrganicCompound114727670 yago:Part113809207 yago:PhysicalEntity100001930 yago:Relation100031921 dbo:Drug yago:Statement106722453 yago:Substance100019613 yago:WikicatAlkenes |
| rdfs:comment |
Talipexole (B-HT920, Domnin) is a dopamine agonist that is marketed as a treatment for Parkinson's Disease in Japan by Boehringer Ingelheim; it was introduced in 1996. As of December 2014 it was not approved for marketing in the US nor in Europe. Talipexole is a D2 dopamine receptor agonist and interacts both pre- and post-synaptic receptors. It also is an α2-adrenergic agonist. (en) |
| rdfs:label |
Talipexole (en) |
| owl:sameAs |
freebase:Talipexole yago-res:Talipexole wikidata:Talipexole dbpedia-fa:Talipexole dbpedia-sh:Talipexole dbpedia-sr:Talipexole https://global.dbpedia.org/id/4vWEv |
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wikipedia-en:Talipexole?oldid=1118537725&ns=0 |
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wiki-commons:Special:FilePath/Talipexole-3D-balls.png wiki-commons:Special:FilePath/Talipexole.svg wiki-commons:Special:FilePath/Talipexole_synthesis.svg |
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wikipedia-en:Talipexole |
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dbr:C10H15N3S |
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| is foaf:primaryTopic of |
wikipedia-en:Talipexole |
