Tesamorelin (original) (raw)

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dbo:abstract تيسامورلين Tesamorelin (الاسم التجاري Egrifta) هو شكل صناعي لمطلق هرمون النمو growth-hormone-releasing hormone (GHRH) الذي يستخدم في علاج المرتبطة بفيروس نقص المناعة البشرية. ويتم إنتاجه بواسطة شركة Theratechnologies, Inc. في كندا. تيسامورلين هو ببتيد اصطناعي يتألف من جميع الأحماض الأمينية 44 لل GHRH عند الإنسان مع إضافة مجموعة حمض العابرة-3-hexenoic. [1] (ar) Tesamorelin (INN) (trade name Egrifta SV) is a synthetic form of growth-hormone-releasing hormone (GHRH) which is used in the treatment of HIV-associated lipodystrophy, approved initially in 2010. It is produced and developed by Theratechnologies, Inc. of Canada. The drug is a synthetic peptide consisting of all 44 amino acids of human GHRH with the addition of a trans-3-hexenoic acid group. (en) Tesamorelin (nome commerciale Egrifta ) è un analogo dell'ormone di rilascio della somatotropina umano (GHRH), utilizzato nel trattamento della lipodistrofia HIV-associata . Tesamorelin è prodotto e sviluppato da del Canada. Tesamorelin è un peptide sintetico costituito da tutti i 44 aminoacidi di GHRH umano con l'aggiunta di un gruppo acido trans-3-hexenoic. (it) Tesamorelin (nome comercial Egrifta) é um fármaco aprovado pelo FDA em novembro de 2010 para tratamento da lipodistrofia associada ao HIV. (pt)
dbo:alternativeName Egrifta SV (en)
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dbo:chEBI 63626
dbo:fdaUniiCode LGW5H38VE3 MQG94M5EEO
dbo:kegg D09015
dbo:medlinePlus a611035
dbo:pubchem 16137828
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dbp:atcPrefix H01 (en)
dbp:atcSuffix AC06 (en)
dbp:bioavailability ≤4% (en)
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dbp:casNumber 218949 (xsd:integer) 901758 (xsd:integer)
dbp:chebi 63626 (xsd:integer)
dbp:chemspiderid 34982925 (xsd:integer)
dbp:eliminationHalfLife -2280.0
dbp:excretion Renal/proteolysis (en)
dbp:h 366 (xsd:integer)
dbp:index2Label as salt (en)
dbp:kegg D09015 (en)
dbp:legalStatus ℞-only (en)
dbp:legalUs Rx-only (en)
dbp:medlineplus a611035 (en)
dbp:metabolism dbr:Proteolysis
dbp:n 72 (xsd:integer)
dbp:o 67 (xsd:integer)
dbp:pregnancyUs X (en)
dbp:pubchem 16137828 (xsd:integer)
dbp:routesOfAdministration dbr:Subcutaneous_injection
dbp:s 1 (xsd:integer)
dbp:smiles CCC[C@@H]NC[C@H]NC[C@H]NC[C@@H]NC[C@H]NCCNC[C@H]NC[C@H]NC[C@H]NC[C@H]NC[C@H]NC[C@H]NCCNC[C@H]NC[C@H]NC[C@H]NC[C@H]NC[C@H]NC[C@H]NC[C@H]NC[C@H]NC[C@H]NC[C@H]NC[C@H]NC[C@H]NC[C@H]NC[C@H]NC[C@H]NC[C@H]NCCNC[C@H]NC[C@H]NC[C@H]NC[C@H]NC[C@H]NC[C@H]NC[C@H]NC[C@H]NC[C@H]NC[C@H]NC[C@H]NC[C@H]NC[C@H]NC[C@H]NCC/C=C/CC (en)
dbp:stdinchi 1 (xsd:integer)
dbp:stdinchikey VQFDKKWXORFBDI-VAVVJCQZSA-N (en)
dbp:tradename Egrifta SV (en)
dbp:unii LGW5H38VE3 (en) MQG94M5EEO (en)
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gold:hypernym dbr:Form
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rdfs:comment تيسامورلين Tesamorelin (الاسم التجاري Egrifta) هو شكل صناعي لمطلق هرمون النمو growth-hormone-releasing hormone (GHRH) الذي يستخدم في علاج المرتبطة بفيروس نقص المناعة البشرية. ويتم إنتاجه بواسطة شركة Theratechnologies, Inc. في كندا. تيسامورلين هو ببتيد اصطناعي يتألف من جميع الأحماض الأمينية 44 لل GHRH عند الإنسان مع إضافة مجموعة حمض العابرة-3-hexenoic. [1] (ar) Tesamorelin (INN) (trade name Egrifta SV) is a synthetic form of growth-hormone-releasing hormone (GHRH) which is used in the treatment of HIV-associated lipodystrophy, approved initially in 2010. It is produced and developed by Theratechnologies, Inc. of Canada. The drug is a synthetic peptide consisting of all 44 amino acids of human GHRH with the addition of a trans-3-hexenoic acid group. (en) Tesamorelin (nome commerciale Egrifta ) è un analogo dell'ormone di rilascio della somatotropina umano (GHRH), utilizzato nel trattamento della lipodistrofia HIV-associata . Tesamorelin è prodotto e sviluppato da del Canada. Tesamorelin è un peptide sintetico costituito da tutti i 44 aminoacidi di GHRH umano con l'aggiunta di un gruppo acido trans-3-hexenoic. (it) Tesamorelin (nome comercial Egrifta) é um fármaco aprovado pelo FDA em novembro de 2010 para tratamento da lipodistrofia associada ao HIV. (pt)
rdfs:label تيسامورلين (ar) Tesamorelin (it) Tesamorelin (en) Tesamorelin (pt)
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