Thiostrepton (original) (raw)

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Thiostrepton is a natural cyclic oligopeptide antibiotic of the thiopeptide class, derived from several strains of streptomycetes, such as Streptomyces azureus and Streptomyces laurentii. Thiostrepton is a natural product of the ribosomally synthesized and post-translationally modified peptide (RiPP) class.

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dbo:abstract Thiostrepton is a natural cyclic oligopeptide antibiotic of the thiopeptide class, derived from several strains of streptomycetes, such as Streptomyces azureus and Streptomyces laurentii. Thiostrepton is a natural product of the ribosomally synthesized and post-translationally modified peptide (RiPP) class. (en) チオストレプトン（英：Thiostrepton）とはストレプトマイセス属の細菌によって生合成される、環形オリゴペプチド系（チオペプチド系）抗生物質であり、複素環含有リボソーム翻訳系翻訳後修飾ペプチド（RiPPs）に分類される。Streptomyces azureusやStreptomyces laurentiiなどから単離することができる。 (ja)
dbo:alternativeName Alaninamide, Bryamycin, Thiactin (en)
dbo:iupacName N-[3-[(3-amino-3-oxoprop-1-en-2-yl)amino]-3-oxoprop-1-en-2-yl]-2-[(1R,8S,11Z,18S,25S,26R,53S,59S)-37-butan-2-yl-18-[(2S,3R)-2,3-dihydroxybutan-2-yl]-11-ethylidene-59-hydroxy-8-[(1R)-1-hydroxyethyl]-31-[(1S)-1-hydroxyethyl]-26,40,46-trimethyl-43-methylidene-6,9,16,23,28,38,41,44,47-nonaoxo-27-oxa-3,13,20,56-tetrathia-7,10,17,24,36,39,42,45,48,52,58,61,62,63,64-pentadecazanonacyclo[23.23.9.329,35.12,5.112,15.119,22.154,57.01,53.032,60]tetrahexaconta-2(64),4,12(63),19(62),21,29(61),30,32(60),33,51,54,57-dodecaen-51-yl]-1,3-thiazole-4-carboxamide (en)
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dbo:wikiPageWikiLink dbr:Antibiotic dbc:Thiopeptides dbc:Antibiotics dbc:Heterocyclic_compounds_with_7_or_more_rings dbr:Mastitis dbr:Natural_product dbr:Oligopeptide dbr:Steroid dbr:Streptomyces dbr:Gram-negative dbr:Methanol dbr:Neomycin dbr:Nystatin dbr:FOXM1 dbr:Streptomyces_azureus dbr:Streptomyces_laurentii dbr:Thiopeptide dbr:K.C._Nicolaou dbr:Dorothy_Crowfoot_Hodgkin dbr:RiPPs dbr:File:Alternative_Mechanism_for_the_deh...eridine_thiopeptides_biosynthesis.png dbr:File:Biosynthesis_of_Thiostrepton.png dbr:File:Thiostrepton_building_block.png dbr:File:Total_synthesis_of_thiostrepton.png
dbp:imagefile Thiostrepton.png (en)
dbp:imagesize 250 (xsd:integer)
dbp:iupacname N-[3-[amino]-3-oxoprop-1-en-2-yl]-2-[-37-butan-2-yl-18-[-2,3-dihydroxybutan-2-yl]-11-ethylidene-59-hydroxy-8-[-1-hydroxyethyl]-31-[-1-hydroxyethyl]-26,40,46-trimethyl-43-methylidene-6,9,16,23,28,38,41,44,47-nonaoxo-27-oxa-3,13,20,56-tetrathia-7,10,17,24,36,39,42,45,48,52,58,61,62,63,64-pentadecazanonacyclo[23.23.9.329,35.12,5.112,15.119,22.154,57.01,53.032,60]tetrahexaconta-2,4,12,19,21,29,30,32,33,51,54,57-dodecaen-51-yl]-1,3-thiazole-4-carboxamide (en)
dbp:othernames Alaninamide, Bryamycin, Thiactin (en)
dbp:verifiedfields changed (en)
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dbp:watchedfields changed (en)
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dct:subject dbc:Thiopeptides dbc:Antibiotics dbc:Heterocyclic_compounds_with_7_or_more_rings
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rdfs:comment Thiostrepton is a natural cyclic oligopeptide antibiotic of the thiopeptide class, derived from several strains of streptomycetes, such as Streptomyces azureus and Streptomyces laurentii. Thiostrepton is a natural product of the ribosomally synthesized and post-translationally modified peptide (RiPP) class. (en) チオストレプトン（英：Thiostrepton）とはストレプトマイセス属の細菌によって生合成される、環形オリゴペプチド系（チオペプチド系）抗生物質であり、複素環含有リボソーム翻訳系翻訳後修飾ペプチド（RiPPs）に分類される。Streptomyces azureusやStreptomyces laurentiiなどから単離することができる。 (ja)
rdfs:label チオストレプトン (ja) Thiostrepton (en)
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