| dbo:abstract |
تريمتريكست هو من مشتقات الكينازولين. وهو مثبط مختزلة ثنائي الهيدروفولات. (ar) Trimetrexate is a quinazoline derivative. It is a dihydrofolate reductase inhibitor. (en) Il trimetrexato è un derivato del composto eterociclico chinazolina, un inibitore della diidrofolato reduttasi, con proprietà generali simili a quelle del metotrexato. (it) |
| dbo:casNumber |
52128-35-5 |
| dbo:chEMBL |
119 |
| dbo:drugbank |
DB01157 |
| dbo:fdaUniiCode |
UPN4ITI8T4 |
| dbo:kegg |
D06238 |
| dbo:medlinePlus |
a694019 |
| dbo:pubchem |
5583 |
| dbo:thumbnail |
wiki-commons:Special:FilePath/Trimetrexate.svg?width=300 |
| dbo:wikiPageID |
5958055 (xsd:integer) |
| dbo:wikiPageLength |
3641 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID |
993555636 (xsd:integer) |
| dbo:wikiPageWikiLink |
dbc:Mammalian_dihydrofolate_reductase_inhibitors dbr:Quinazoline dbc:Aromatic_amines dbc:Phenol_ethers dbr:Leiomyosarcoma dbc:Fungal_dihydrofolate_reductase_inhibitors dbr:Dihydrofolate_reductase_inhibitor dbc:Protozoal_dihydrofolate_reductase_inhibitors dbc:Anilines dbc:Quinazolines dbc:Antifungals dbc:Antiprotozoal_agents dbr:Methotrexate dbr:Pneumocystis_pneumonia dbr:Leucovorin |
| dbp:atcPrefix |
P01 (en) |
| dbp:atcSuffix |
AX07 (en) |
| dbp:bioavailability |
VD: 20-30 Liters (en) |
| dbp:c |
19 (xsd:integer) |
| dbp:casNumber |
52128 (xsd:integer) |
| dbp:chembl |
119 (xsd:integer) |
| dbp:chemspiderid |
5381 (xsd:integer) |
| dbp:drugbank |
DB01157 (en) |
| dbp:eliminationHalfLife |
43200.0 |
| dbp:h |
23 (xsd:integer) |
| dbp:iupacName |
5 (xsd:integer) |
| dbp:iupharLigand |
7613 (xsd:integer) |
| dbp:kegg |
D06238 (en) |
| dbp:medlineplus |
a694019 (en) |
| dbp:metabolism |
Oxidative O-demethylation, followed by conjugation with glucuronide or sulfate (en) |
| dbp:n |
5 (xsd:integer) |
| dbp:o |
3 (xsd:integer) |
| dbp:pubchem |
5583 (xsd:integer) |
| dbp:smiles |
n3c1ccN (en) |
| dbp:stdinchi |
1 (xsd:integer) |
| dbp:stdinchikey |
NOYPYLRCIDNJJB-UHFFFAOYSA-N (en) |
| dbp:unii |
UPN4ITI8T4 (en) |
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470615984 (xsd:integer) |
| dbp:width |
250 (xsd:integer) |
| dbp:wikiPageUsesTemplate |
dbt:Antimicrobial-stub dbt:Drugbox dbt:Reflist dbt:Cascite dbt:Chemspidercite dbt:Drugbankcite dbt:Ebicite dbt:Fdacite dbt:Keggcite dbt:Stdinchicite dbt:Drugs.com dbt:DiseasesDB dbt:MedlinePlusDrugInfo dbt:Agents_against_amoebiasis_and_other_protozoal_diseases |
| dcterms:subject |
dbc:Mammalian_dihydrofolate_reductase_inhibitors dbc:Aromatic_amines dbc:Phenol_ethers dbc:Fungal_dihydrofolate_reductase_inhibitors dbc:Protozoal_dihydrofolate_reductase_inhibitors dbc:Anilines dbc:Quinazolines dbc:Antifungals dbc:Antiprotozoal_agents |
| rdf:type |
owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 yago:WikicatAntifungals yago:WikicatAntiprotozoalAgents yago:WikicatMammalianDihydrofolateReductaseInhibitors yago:Agent109190918 yago:Agent114778436 yago:Antifungal102720201 yago:CausalAgent100007347 yago:Inhibitor114724436 yago:Matter100020827 yago:PhysicalEntity100001930 yago:WikicatFungalDihydrofolateReductaseInhibitors dbo:Drug yago:Substance100020090 yago:WikicatProtozoalDihydrofolateReductaseInhibitors |
| rdfs:comment |
تريمتريكست هو من مشتقات الكينازولين. وهو مثبط مختزلة ثنائي الهيدروفولات. (ar) Trimetrexate is a quinazoline derivative. It is a dihydrofolate reductase inhibitor. (en) Il trimetrexato è un derivato del composto eterociclico chinazolina, un inibitore della diidrofolato reduttasi, con proprietà generali simili a quelle del metotrexato. (it) |
| rdfs:label |
تريمتريكست (ar) Trimetrexato (it) Trimetrexate (en) |
| owl:sameAs |
freebase:Trimetrexate http://www4.wiwiss.fu-berlin.de/drugbank/resource/drugs/DB01157 yago-res:Trimetrexate http://www4.wiwiss.fu-berlin.de/sider/resource/drugs/5582 wikidata:Trimetrexate dbpedia-ar:Trimetrexate dbpedia-it:Trimetrexate dbpedia-sh:Trimetrexate dbpedia-sr:Trimetrexate dbpedia-vi:Trimetrexate https://global.dbpedia.org/id/4wTJv |
| prov:wasDerivedFrom |
wikipedia-en:Trimetrexate?oldid=993555636&ns=0 |
| foaf:depiction |
wiki-commons:Special:FilePath/Trimetrexate.svg |
| foaf:isPrimaryTopicOf |
wikipedia-en:Trimetrexate |
| is dbo:medication of |
dbr:Pneumocystis_pneumonia__Pneumocystis_pneumonia__1 |
| is dbo:wikiPageRedirects of |
dbr:ATC_code_P01AX07 dbr:Neutrexin dbr:Trimetrexate_glucuronate |
| is dbo:wikiPageWikiLink of |
dbr:Diaminopyrimidine dbr:List_of_MeSH_codes_(D03) dbr:ATC_code_P01AX07 dbr:ATC_code_P01 dbr:Heroic_measure dbr:Pneumocystis_pneumonia dbr:List_of_drugs:_Tr–Tri dbr:Neutrexin dbr:Trimetrexate_glucuronate |
| is foaf:primaryTopic of |
wikipedia-en:Trimetrexate |
