| dbo:abstract |
Tse Wen Chang (Chinese: 張子文; pinyin: Zhāng Zǐwén, born August 25, 1947) is an immunology researcher, whose career spans across academia and industry. His early research involving the Immunoglobulin E (IgE) pathway and antibody-based therapeutics lead to the development of omalizumab (also known as Xolair), a medication that has been approved for the treatment of severe allergic asthma and severe chronic spontaneous urticaria. Chang is a cofounder of Tanox, a biopharmaceutical company specialized in anti-IgE therapies for the treatment of allergic diseases. After Tanox's tripartite partnership with Genentech and Novartis was forged in 1996, Chang returned to his alma mater, the National Tsing Hua University in Taiwan and served as the Dean (1996–1999) of the College of Life Sciences. Chang was appointed by the Taiwanese government as President of the Development Center for Biotechnology (DCB) in 2000, and served as a Science and Technology Advisor of the Executive Yuan from 2002 to 2006. From 2006 to 2016, he was tenured as Distinguished Research Fellow at the Genomics Research Center, Academia Sinica. He founded Immunwork, Inc. in 2014. (en) |
| dbo:academicDiscipline |
dbr:Biomedicine dbr:Biotechnology dbr:Immunology |
| dbo:birthDate |
1947-08-25 (xsd:date) |
| dbo:birthPlace |
dbr:Zhongli_District dbr:Taoyuan_County,_Taiwan |
| dbo:doctoralAdvisor |
dbr:Alfred_L._Goldberg |
| dbo:institution |
dbr:Academia_Sinica dbr:National_Tsing_Hua_University dbr:Tanox |
| dbo:knownFor |
dbr:Antibody_microarray dbr:Immunoglobulin_E dbr:Xolair |
| dbo:wikiPageExternalLink |
http://immunwork.com/ http://www.nature.com/nature-newbio/journal/v239/n94/abs/newbio239207a0.html http://www.nature.com/nbt/journal/v18/n2/abs/nbt0200_157.html http://www.nature.com/nbt/journal/v3/n10/abs/nbt1085-905.html http://www.nature.com/nbt/journal/v8/n2/abs/nbt0290-122.html http://www.sciencedirect.com/science/article/pii/S0065277606930028 http://www.sciencedirect.com/science/article/pii/S0065277608004021 http://www.sciencedirect.com/science/article/pii/S0091674906008566 http://www.sciencedirect.com/science/article/pii/S0091674914006575 http://www.jimmunol.org/content/148/1/129 http://www.jimmunol.org/content/184/4/1748.short https://www.nature.com/articles/ncomms4139 https://www.ncbi.nlm.nih.gov/pubmed/6165018 |
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| dbp:birthDate |
1947-08-25 (xsd:date) |
| dbp:birthPlace |
Zhongli District, Taoyuan County, Taiwan (en) |
| dbp:caption |
Chang in office, taken 2016 (en) |
| dbp:doctoralAdvisor |
dbr:Alfred_L._Goldberg |
| dbp:education |
dbr:National_Tsing_Hua_University Harvard University (en) |
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dbr:Biomedicine dbr:Biotechnology dbr:Immunology |
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220 (xsd:integer) |
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dbr:Antibody_microarray dbr:Xolair anti-IgE therapy (en) |
| dbp:name |
(en) Tse Wen Chang (en) |
| dbp:p |
Zhāng Zǐwén (en) |
| dbp:t |
張子文 (en) |
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dbt:Authority_control dbt:Reflist dbt:Zh dbt:Birth_date_and_age dbt:Infobox_scientist |
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dbr:Academia_Sinica dbr:National_Tsing_Hua_University Immunwork, Inc. (en) Tanox, Inc. (en) |
| dcterms:subject |
dbc:People_from_Taoyuan_City dbc:1947_births dbc:Living_people dbc:Taiwanese_biotechnologists dbc:National_Tsing_Hua_University_alumni dbc:Harvard_University_alumni dbc:Taiwanese_expatriates_in_the_United_States dbc:TWAS_laureates dbc:Taiwanese_immunologists |
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| rdfs:comment |
Tse Wen Chang (Chinese: 張子文; pinyin: Zhāng Zǐwén, born August 25, 1947) is an immunology researcher, whose career spans across academia and industry. His early research involving the Immunoglobulin E (IgE) pathway and antibody-based therapeutics lead to the development of omalizumab (also known as Xolair), a medication that has been approved for the treatment of severe allergic asthma and severe chronic spontaneous urticaria. Chang is a cofounder of Tanox, a biopharmaceutical company specialized in anti-IgE therapies for the treatment of allergic diseases. After Tanox's tripartite partnership with Genentech and Novartis was forged in 1996, Chang returned to his alma mater, the National Tsing Hua University in Taiwan and served as the Dean (1996–1999) of the College of Life Sciences. Chang (en) |
| rdfs:label |
Tse Wen Chang (en) |
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wikidata:Tse Wen Chang http://azb.dbpedia.org/resource/تس_ون_چانق dbpedia-fa:Tse Wen Chang https://global.dbpedia.org/id/2nnf8 |
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wikipedia-en:Tse_Wen_Chang?oldid=1037458904&ns=0 |
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wikipedia-en:Tse_Wen_Chang |
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Tse Wen Chang (en) |
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dbr:Tanox |
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dbr:Wen_Chang |
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dbr:Chang_Tse-wen dbr:Zhang_Ziwen |
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wikipedia-en:Tse_Wen_Chang |
