| dbo:abstract |
Ulotaront (INN; developmental codes SEP-363856, SEP-856) is an investigational antipsychotic that is undergoing clinical trials for the treatment of schizophrenia and Parkinson's disease psychosis. The medication was discovered in collaboration between PsychoGenics Inc. and Sunovion Pharmaceuticals using PsychoGenics' behavior and AI-based phenotypic drug discovery platform, SmartCube. Ulotaront is in Phase III of clinical development. Research has shown that ulotaront results in a greater reduction from baseline in the PANSS total score than placebo. Treatment with ulotaront, as compared with placebo, was also associated with an improvement in sleep quality. Ulotaront was awarded a Breakthrough Therapy designation due to its increased efficacy and greatly reduced side effects compared to current treatments. (en) SEP-363856 eller SEP-856, är en antipsykotika som tillhandahålls av Sunovion. SEP-856 befinner sig på utredningstadiet än. (sv) |
| dbo:casNumber |
1310426-33-5 |
| dbo:fdaUniiCode |
3K6270MG59 |
| dbo:kegg |
D12474 |
| dbo:pubchem |
89532783 |
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wiki-commons:Special:FilePath/SEP-363856.svg?width=300 |
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https://adisinsight.springer.com/drugs/800036955 |
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| dbp:kegg |
D12474 (en) |
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1 (xsd:integer) |
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89532783 (xsd:integer) |
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| dbp:smiles |
CNC[C@H]1C2=CC=CS2 (en) |
| dbp:stdinchi |
1 (xsd:integer) |
| dbp:stdinchikey |
ABDDQTDRAHXHOC-QMMMGPOBSA-N (en) |
| dbp:synonyms |
SEP-363856; SEP-856 (en) |
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3 (xsd:integer) |
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dbc:Amines dbc:Experimental_drugs dbc:5-HT1A_agonists dbc:Antipsychotics dbc:TAAR1_agonists dbc:Thiophenes |
| rdf:type |
owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 dbo:Drug |
| rdfs:comment |
SEP-363856 eller SEP-856, är en antipsykotika som tillhandahålls av Sunovion. SEP-856 befinner sig på utredningstadiet än. (sv) Ulotaront (INN; developmental codes SEP-363856, SEP-856) is an investigational antipsychotic that is undergoing clinical trials for the treatment of schizophrenia and Parkinson's disease psychosis. The medication was discovered in collaboration between PsychoGenics Inc. and Sunovion Pharmaceuticals using PsychoGenics' behavior and AI-based phenotypic drug discovery platform, SmartCube. Ulotaront is in Phase III of clinical development. (en) |
| rdfs:label |
Ulotaront (en) SEP-363856 (sv) |
| owl:sameAs |
wikidata:Ulotaront dbpedia-sv:Ulotaront https://global.dbpedia.org/id/9T77f |
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wikipedia-en:Ulotaront?oldid=1122158164&ns=0 |
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wikipedia-en:Ulotaront |
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wikipedia-en:Ulotaront |
