dbo:abstract |
Vanillotoxine (VaTx) sind schmerzauslösende Neurotoxine, die von der Vogelspinne Psalmopoeus cambridgei gebildet werden. (de) Vanillotoxins (VaTxs, subtypes VaTx1, VaTx2, and VaTx3) are neurotoxins found in the venom of the tarantula Psalmopoeus cambridgei. They act as agonists for the transient receptor potential cation channel subfamily V member 1 (TRPV1), activating the pain sensory system. VaTx1 and 2 also act as antagonists for the Kv2-type voltage-gated potassium channel (Kv2), inducing paralytic behavior in small animals. (en) |
dbo:alternativeName |
Tau-theraphotoxin-Pc1a, VaTx1 (en) |
dbo:thumbnail |
wiki-commons:Special:FilePath/VaTx1.jpg?width=300 |
dbo:wikiPageID |
37328591 (xsd:integer) |
dbo:wikiPageLength |
4165 (xsd:nonNegativeInteger) |
dbo:wikiPageRevisionID |
1052377958 (xsd:integer) |
dbo:wikiPageWikiLink |
dbr:EC50 dbr:Inhibitor_cystine_knot dbr:Psalmopoeus_cambridgei dbr:TRPV1 dbr:Peripheral_nervous_system dbr:Trinidad dbr:Agonists dbr:KCNB1 dbr:KCNIP2 dbc:Neurotoxins dbr:Tarantula dbc:Ion_channel_toxins dbc:Spider_toxins dbr:Neuromuscular_junction dbr:Neurotoxins dbr:Transient_receptor_potential_cation_channel |
dbp:imagealt |
Chemical structure of VaTx1 (en) |
dbp:imagefile |
VaTx1.JPG (en) |
dbp:name |
Vanillotoxin-1 (en) |
dbp:othernames |
Tau-theraphotoxin-Pc1a, VaTx1 (en) |
dbp:wikiPageUsesTemplate |
dbt:Chembox dbt:Chembox_Identifiers dbt:Chembox_Properties dbt:Reflist dbt:Neurotoxins dbt:Toxins |
dcterms:subject |
dbc:Neurotoxins dbc:Ion_channel_toxins dbc:Spider_toxins |
gold:hypernym |
dbr:Neurotoxins |
rdf:type |
owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q11173 yago:WikicatNeurotoxins yago:Matter100020827 yago:Neurotoxin115036321 yago:PhysicalEntity100001930 yago:Poison115032376 yago:WikicatInvertebrateToxins yago:WikicatIonChannelToxins dbo:ChemicalCompound yago:Substance100020090 yago:Toxin115034074 |
rdfs:comment |
Vanillotoxine (VaTx) sind schmerzauslösende Neurotoxine, die von der Vogelspinne Psalmopoeus cambridgei gebildet werden. (de) Vanillotoxins (VaTxs, subtypes VaTx1, VaTx2, and VaTx3) are neurotoxins found in the venom of the tarantula Psalmopoeus cambridgei. They act as agonists for the transient receptor potential cation channel subfamily V member 1 (TRPV1), activating the pain sensory system. VaTx1 and 2 also act as antagonists for the Kv2-type voltage-gated potassium channel (Kv2), inducing paralytic behavior in small animals. (en) |
rdfs:label |
Vanillotoxine (de) Vanillotoxin (en) |
owl:sameAs |
freebase:Vanillotoxin yago-res:Vanillotoxin wikidata:Vanillotoxin dbpedia-de:Vanillotoxin https://global.dbpedia.org/id/4xEjJ |
prov:wasDerivedFrom |
wikipedia-en:Vanillotoxin?oldid=1052377958&ns=0 |
foaf:depiction |
wiki-commons:Special:FilePath/VaTx1.jpg |
foaf:isPrimaryTopicOf |
wikipedia-en:Vanillotoxin |
foaf:name |
Vanillotoxin-1 (en) |
is dbo:wikiPageWikiLink of |
dbr:Capsaicin dbr:Double-knot_toxin dbr:Inhibitor_cystine_knot dbr:Psalmopoeus_cambridgei dbr:TRPV1 dbr:Spider_bite dbr:Psalmotoxin dbr:RhTx |
is foaf:primaryTopic of |
wikipedia-en:Vanillotoxin |