VqmR sRNA (original) (raw)
VqmR small RNA was discovered in Vibrio cholerae, a bacterium which can cause cholera, using differential RNA sequencing (sRNA-seq) under conditions of low and high cell density which were being used to study quorum sensing (QS). QS controls virulence and biofilm formation in Vibrio cholerae; it has been shown previously that it is directed by the Qrr sRNAs. VqmR has been shown to repress the expression of multiple mRNAs including the rtx (repeats in toxin) toxin genes and the vpsT , which is required for biofilm formation. In fact, VqmR which is highly conserved in vibrionaceae, was shown to strongly inhibit biofilm formation by repressing the vpsT gene; it could be the link between biofilm formation and QS.
| Property | Value |
|---|---|
| dbo:abstract | VqmR small RNA was discovered in Vibrio cholerae, a bacterium which can cause cholera, using differential RNA sequencing (sRNA-seq) under conditions of low and high cell density which were being used to study quorum sensing (QS). QS controls virulence and biofilm formation in Vibrio cholerae; it has been shown previously that it is directed by the Qrr sRNAs. VqmR has been shown to repress the expression of multiple mRNAs including the rtx (repeats in toxin) toxin genes and the vpsT , which is required for biofilm formation. In fact, VqmR which is highly conserved in vibrionaceae, was shown to strongly inhibit biofilm formation by repressing the vpsT gene; it could be the link between biofilm formation and QS. (en) |
| dbo:thumbnail | wiki-commons:Special:FilePath/RF02834.svg?width=300 |
| dbo:wikiPageID | 56022486 (xsd:integer) |
| dbo:wikiPageLength | 2729 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID | 1057323986 (xsd:integer) |
| dbo:wikiPageWikiLink | dbr:Biofilm dbr:MRNA dbr:Vibrio_cholerae dbr:Conserved_sequence dbr:Bacteria dbc:Non-coding_RNA dbr:Quorum_sensing dbr:Bacterial_small_RNA dbr:Cholera dbr:Virulence dbr:Sequence_conservation dbr:Small_RNA dbr:Secondary_structure dbr:Gene_repression dbr:RNA_sequencing |
| dbp:caption | Predicted secondary structure and sequence conservation of VqmR small RNA (en) |
| dbp:go | , , (en) |
| dbp:name | VqmR sRNA (en) |
| dbp:rfam | RF02834 (en) |
| dbp:taxDomain | dbr:Bacteria |
| dbp:wikiPageUsesTemplate | dbt:Not_a_typo dbt:Reflist dbt:GO dbt:SO dbt:Infobox_rfam dbt:Molecular-cell-biology-stub |
| dcterms:subject | dbc:Non-coding_RNA |
| rdfs:comment | VqmR small RNA was discovered in Vibrio cholerae, a bacterium which can cause cholera, using differential RNA sequencing (sRNA-seq) under conditions of low and high cell density which were being used to study quorum sensing (QS). QS controls virulence and biofilm formation in Vibrio cholerae; it has been shown previously that it is directed by the Qrr sRNAs. VqmR has been shown to repress the expression of multiple mRNAs including the rtx (repeats in toxin) toxin genes and the vpsT , which is required for biofilm formation. In fact, VqmR which is highly conserved in vibrionaceae, was shown to strongly inhibit biofilm formation by repressing the vpsT gene; it could be the link between biofilm formation and QS. (en) |
| rdfs:label | VqmR sRNA (en) |
| owl:sameAs | wikidata:VqmR sRNA https://global.dbpedia.org/id/4Y6ZA |
| prov:wasDerivedFrom | wikipedia-en:VqmR_sRNA?oldid=1057323986&ns=0 |
| foaf:depiction | wiki-commons:Special:FilePath/RF02834.svg |
| foaf:isPrimaryTopicOf | wikipedia-en:VqmR_sRNA |
| is dbo:wikiPageWikiLink of | dbr:Vibrio |
| is rdfs:seeAlso of | dbr:Bacterial_small_RNA |
| is foaf:primaryTopic of | wikipedia-en:VqmR_sRNA |
