YOYO-1 (original) (raw)
YOYO-1 is a green fluorescent dye used in DNA staining. It belongs to the family of monomethine cyanine dyes and is a tetracationic homodimer of (abbreviated YO, hence the name YOYO), typically available as tetraiodide salt. In aqueous buffer, free YOYO-1 dye (absorption: λmax 458 nm, emission: λmax 564 nm) has very low fluorescence quantum yield, however the intensity of fluorescence increases 3200 times upon binding through bis-intercalation to double-stranded DNA (absorption: λmax 489 nm, emission: λmax 509 nm).
| Property | Value |
|---|---|
| dbo:abstract | YOYO-1 is a green fluorescent dye used in DNA staining. It belongs to the family of monomethine cyanine dyes and is a tetracationic homodimer of (abbreviated YO, hence the name YOYO), typically available as tetraiodide salt. In aqueous buffer, free YOYO-1 dye (absorption: λmax 458 nm, emission: λmax 564 nm) has very low fluorescence quantum yield, however the intensity of fluorescence increases 3200 times upon binding through bis-intercalation to double-stranded DNA (absorption: λmax 489 nm, emission: λmax 509 nm). (en) |
| dbo:alternativeName | YOYO, YOYO-1, YoYo-1 (en) |
| dbo:iupacName | [12(2)Z,16(172)Z]-13,7,7,11,11,173-Hexamethyl-13H,173H-7,11-diaza-31λ5,151λ5-3(4,1),15(1,4)-diquinolina-1,17(2)-bis([1,3]benzoxazola)heptadecaphane-12(2),16(172)-diene-7,11-diium-31,151-bis(ylium) tetraiodide (en) |
| dbo:thumbnail | wiki-commons:Special:FilePath/YOYO-1_fluorescent_dye.png?width=300 |
| dbo:wikiPageID | 37975557 (xsd:integer) |
| dbo:wikiPageLength | 8767 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID | 1096819817 (xsd:integer) |
| dbo:wikiPageWikiLink | dbc:Cyanine_dyes dbr:Cyanine dbr:DNA dbr:Dexter_electron_transfer dbc:DNA dbr:Quantum_yield dbr:Staining_(biology) dbr:Fluorescence_microscope dbr:Molar_attenuation_coefficient dbr:Photoisomerization dbr:Super-resolution_microscopy dbr:Fluorescent_dye dbr:File:YOYO-1_fluorescent_dye_synthesis.png dbr:Oxazole_Yellow |
| dbp:imagefile | YOYO-1_fluorescent_dye.png (en) |
| dbp:imagesize | 238 (xsd:integer) |
| dbp:othernames | YOYO, YOYO-1, YoYo-1 (en) |
| dbp:pin | [12Z,16Z]-13,7,7,11,11,173-Hexamethyl-13H,173H-7,11-diaza-31λ5,151λ5-3,15-diquinolina-1,17-bisheptadecaphane-12,16-diene-7,11-diium-31,151-bis tetraiodide (en) |
| dbp:wikiPageUsesTemplate | dbt:Chembox dbt:Chembox_Identifiers dbt:Chembox_Properties dbt:Reflist dbt:Cascite dbt:Fdacite |
| dcterms:subject | dbc:Cyanine_dyes dbc:DNA |
| gold:hypernym | dbr:Dye |
| rdf:type | owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q11173 yago:AbsorptionIndicator114598383 yago:Abstraction100002137 yago:ColoringMaterial114984973 yago:Dye114985383 yago:Fluorescein114987695 yago:Indicator114917208 yago:Material114580897 yago:Matter100020827 yago:Part113809207 yago:PhysicalEntity100001930 yago:Relation100031921 dbo:ChemicalCompound yago:Substance100019613 yago:WikicatFluorescentDyes |
| rdfs:comment | YOYO-1 is a green fluorescent dye used in DNA staining. It belongs to the family of monomethine cyanine dyes and is a tetracationic homodimer of (abbreviated YO, hence the name YOYO), typically available as tetraiodide salt. In aqueous buffer, free YOYO-1 dye (absorption: λmax 458 nm, emission: λmax 564 nm) has very low fluorescence quantum yield, however the intensity of fluorescence increases 3200 times upon binding through bis-intercalation to double-stranded DNA (absorption: λmax 489 nm, emission: λmax 509 nm). (en) |
| rdfs:label | YOYO-1 (en) |
| owl:sameAs | freebase:YOYO-1 yago-res:YOYO-1 wikidata:YOYO-1 dbpedia-sh:YOYO-1 dbpedia-sr:YOYO-1 https://global.dbpedia.org/id/4xxH4 |
| prov:wasDerivedFrom | wikipedia-en:YOYO-1?oldid=1096819817&ns=0 |
| foaf:depiction | wiki-commons:Special:FilePath/YOYO-1_fluorescent_dye.png wiki-commons:Special:FilePath/YOYO-1_fluorescent_dye_synthesis.png |
| foaf:isPrimaryTopicOf | wikipedia-en:YOYO-1 |
| is dbo:wikiPageWikiLink of | dbr:Fluorophore |
| is foaf:primaryTopic of | wikipedia-en:YOYO-1 |
