Thioredoxin in the cardiovascular system (original) (raw)

References

1. Nordberg J, Arner ES (2001) Reactive oxygen species, antioxidants, and the mammalian thioredoxin system. Free Radic Biol Med 31:1287–1312
   Article PubMed CAS Google Scholar
2. Powis G, Briehl M, Oblong J (1995) Redox signalling and the control of cell growth and death. Pharmacol Ther 68:149–173
   Article PubMed CAS Google Scholar
3. Chae HZ, Chung SJ, Rhee SG (1994) Thioredoxin-dependent peroxide reductase from yeast. J Biol Chem 269:27670–27678
   PubMed CAS Google Scholar
4. Kang SW, Chae HZ, Seo MS, Kim K, Baines IC, Rhee SG (1998) Mammalian peroxiredoxin isoforms can reduce hydrogen peroxide generated in response to growth factors and tumor necrosis factor-alpha. J Biol Chem 273:6297–6302
   Article PubMed CAS Google Scholar
5. Spyrou G, Enmark E, Miranda-Vizuete A, Gustafsson J (1997) Cloning and expression of a novel mammalian thioredoxin. J Biol Chem 272:2936–2941
   Article PubMed CAS Google Scholar
6. Tanaka T, Hosoi F, Yamaguchi-Iwai Y, Nakamura H, Masutani H, Ueda S, Nishiyama A, Takeda S, Wada H, Spyrou G et al (2002) Thioredoxin-2 (TRX-2) is an essential gene regulating mitochondria-dependent apoptosis. Embo J 21:1695–1703
   Article PubMed CAS Google Scholar
7. Matthews JR, Wakasugi N, Virelizier JL, Yodoi J, Hay RT (1992) Thioredoxin regulates the DNA binding activity of NF-kappa B by reduction of a disulphide bond involving cysteine 62. Nucleic Acids Res 20:3821–3830
   PubMed CAS Google Scholar
8. Hirota K, Matsui M, Iwata S, Nishiyama A, Mori K, Yodoi J (1997) AP-1 transcriptional activity is regulated by a direct association between thioredoxin and Ref-1. Proc Natl Acad Sci USA 94:3633–3638
   Article PubMed CAS Google Scholar
9. Powis G, Mustacich D, Coon A (2000) The role of the redox protein thioredoxin in cell growth and cancer. Free Radic Biol Med 29:312–322
   Article PubMed CAS Google Scholar
10. Okuda M, Inoue N, Azumi H, Seno T, Sumi Y, Hirata K, Kawashima S, Hayashi Y, Itoh H, Yodoi J et al (2001) Expression of glutaredoxin in human coronary arteries: its potential role in antioxidant protection against atherosclerosis. Arterioscler Thromb Vasc Biol 21:1483–1487
    PubMed CAS Google Scholar
11. Nakamura H, Matsuda M, Furuke K, Kitaoka Y, Iwata S, Toda K, Inamoto T, Yamaoka Y, Ozawa K, Yodoi J (1994) Adult T cell leukemia-derived factor/human thioredoxin protects endothelial F-2 cell injury caused by activated neutrophils or hydrogen peroxide. Immunol Lett 42:75–80
    Article PubMed CAS Google Scholar
12. Haendeler J, Hoffmann J, Zeiher AM, Dimmeler S (2004) Antioxidant effects of statins via S-nitrosylation and activation of thioredoxin in endothelial cells: a novel vasculoprotective function of statins. Circulation 110:856–861
    Article PubMed CAS Google Scholar
13. Schulze PC, De Keulenaer GW, Yoshioka J, Kassik KA, Lee RT (2002) Vitamin D3-upregulated protein-1 (VDUP-1) regulates redox-dependent vascular smooth muscle cell proliferation through interaction with thioredoxin. Circ Res 91:689–695
    Article PubMed CAS Google Scholar
14. Takagi Y, Gon Y, Todaka T, Nozaki K, Nishiyama A, Sono H, Hashimoto N, Kikuchi H, Yodoi J (1998) Expression of thioredoxin is enhanced in atherosclerotic plaques and during neointima formation in rat arteries. Lab Invest 78:957–966
    PubMed CAS Google Scholar
15. Furman C, Rundlof AK, Larigauderie G, Jaye M, Bricca G, Copin C, Kandoussi AM, Fruchart JC, Arner ES, Rouis M (2004) Thioredoxin reductase 1 is upregulated in atherosclerotic plaques: specific induction of the promoter in human macrophages by oxidized low-density lipoproteins. Free Radic Biol Med 37:71–85
    Article PubMed CAS Google Scholar
16. Tanito M, Nakamura H, Kwon YW, Teratani A, Masutani H, Shioji K, Kishimoto C, Ohira A, Horie R, Yodoi J (2004) Enhanced oxidative stress and impaired thioredoxin expression in spontaneously hypertensive rats. Antioxid Redox Signal 6:89–97
    Article PubMed CAS Google Scholar
17. Yamagata K, Tagami M, Ikeda K, Yamori Y, Nara Y (2000) Altered gene expressions during hypoxia and reoxygenation in cortical neurons isolated from stroke-prone spontaneously hypertensive rats. Neurosci Lett 284:131–134
    Article PubMed CAS Google Scholar
18. Beckman JS, Koppenol WH (1996) Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly. Am J Physiol 271:C1424–1437
    PubMed CAS Google Scholar
19. Turoczi T, Chang VW, Engelman RM, Maulik N, Ho YS, Das DK (2003) Thioredoxin redox signaling in the ischemic heart: an insight with transgenic mice overexpressing Trx1. J Mol Cell Cardiol 35:695–704
    Article PubMed CAS Google Scholar
20. Yamamoto M, Yang G, Hong C, Liu J, Holle E, Yu X, Wagner T, Vatner SF, Sadoshima J (2003) Inhibition of endogenous thioredoxin in the heart increases oxidative stress and cardiac hypertrophy. J Clin Invest 112:1395–1406
    Article PubMed CAS Google Scholar
21. Kuster GM, Pimentel DR, Adachi T, Ido Y, Brenner DA, Cohen RA, Liao R, Siwik DA, Colucci WS (2005) Alpha-adrenergic receptor-stimulated hypertrophy in adult rat ventricular myocytes is mediated via thioredoxin-1-sensitive oxidative modification of thiols on Ras. Circulation 111:1192–1198
    Article PubMed CAS Google Scholar
22. Aota M, Matsuda K, Isowa N, Wada H, Yodoi J, Ban T (1996) Protection against reperfusion-induced arrhythmias by human thioredoxin. J Cardiovasc Pharmacol 27:727–732
    Article PubMed CAS Google Scholar
23. Shioji K, Kishimoto C, Nakamura H, Masutani H, Yuan Z, Oka S, Yodoi J (2002) Overexpression of thioredoxin-1 in transgenic mice attenuates adriamycin-induced cardiotoxicity. Circulation 106:1403–1409
    Article PubMed CAS Google Scholar
24. Liu W, Nakamura H, Shioji K, Tanito M, Oka S, Ahsan MK, Son A, Ishii Y, Kishimoto C, Yodoi J (2004) Thioredoxin-1 ameliorates myosin-induced autoimmune myocarditis by suppressing chemokine expressions and leukocyte chemotaxis in mice. Circulation 110:1276–1283
    Article PubMed CAS Google Scholar
25. Tao L, Gao E, Bryan NS, Qu Y, Liu HR, Hu A, Christopher TA, Lopez BL, Yodoi J, Koch WJ et al (2004) Cardioprotective effects of thioredoxin in myocardial ischemia and the reperfusion role of S-nitrosation. Proc Natl Acad Sci USA 101:11471–11476
    Article PubMed Google Scholar
26. Haendeler J, Hoffmann J, Tischler V, Berk BC, Zeiher AM, Dimmeler S (2002) Redox regulatory and anti-apoptotic functions of thioredoxin depend on S-nitrosylation at cysteine 69. Nat Cell Biol 4:743–749
    Article PubMed CAS Google Scholar
27. Nakamura H, De Rosa S, Roederer M, Anderson MT, Dubs JG, Yodoi J, Holmgren A, Herzenberg LA (1996) Elevation of plasma thioredoxin levels in HIV-infected individuals. Int Immunol 8:603–611
    PubMed CAS Google Scholar
28. Yoshida S, Katoh T, Tetsuka T, Uno K, Matsui N, Okamoto T (1999) Involvement of thioredoxin in rheumatoid arthritis: its costimulatory roles in the TNF-alpha-induced production of IL-6 and IL-8 from cultured synovial fibroblasts. J Immunol 163:351–358
    PubMed CAS Google Scholar
29. Kishimoto C, Shioji K, Nakamura H, Nakayama Y, Yodoi J, Sasayama S (2001) Serum thioredoxin (TRX) levels in patients with heart failure. Jpn Circ J 65:491–494
    Article PubMed CAS Google Scholar
30. Jekell A, Hossain A, Alehagen U, Dahlstrom U, Rosen A (2004) Elevated circulating levels of thioredoxin and stress in chronic heart failure. Eur J Heart Fail 6:883–890
    PubMed CAS Google Scholar
31. Miyamoto M, Kishimoto C, Shioji K, Lee JD, Shimizu H, Ueda T, Yodoi J (2003) Cutaneous arteriolar thioredoxin expression in patients with heart failure. Circ J 67:116–118
    Article PubMed CAS Google Scholar
32. Miyamoto M, Kishimoto C, Nimata M, Nakamura H, Yodoi J (2004) Thioredoxin, a redox-regulating protein, is expressed in spontaneous myocarditis in inbred strains of mice. Int J Cardiol 95:315–319
    Article PubMed Google Scholar
33. Hokamaki J, Kawano H, Soejima H, Miyamoto S, Kajiwara I, Kojima S, Sakamoto T, Sugiyama S, Yoshimura M, Nakamura H et al (2005) Plasma thioredoxin levels in patients with unstable angina. Int J Cardiol 99:225–231
    Article PubMed Google Scholar
34. Ichijo H, Nishida E, Irie K, ten Dijke P, Saitoh M, Moriguchi T, Takagi M, Matsumoto K, Miyazono K, Gotoh Y (1997) Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways. Science 275:90–94
    Article PubMed CAS Google Scholar
35. Saitoh M, Nishitoh H, Fujii M, Takeda K, Tobiume K, Sawada Y, Kawabata M, Miyazono K, Ichijo H (1998) Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1. Embo J 17:2596–2606
    Article PubMed CAS Google Scholar
36. Chen KS, DeLuca HF (1994) Isolation and characterization of a novel cDNA from HL-60 cells treated with 1,25-dihydroxyvitamin D-3. Biochim Biophys Acta 1219:26–32
    PubMed CAS Google Scholar
37. Nishiyama A, Matsui M, Iwata S, Hirota K, Masutani H, Nakamura H, Takagi Y, Sono H, Gon Y, Yodoi J (1999) Identification of thioredoxin-binding protein-2/vitamin D(3) up-regulated protein 1 as a negative regulator of thioredoxin function and expression. J Biol Chem 274:21645–21650
    Article PubMed CAS Google Scholar
38. Junn E, Han SH, Im JY, Yang Y, Cho EW, Um HD, Kim DK, Lee KW, Han PL, Rhee SG et al (2000) Vitamin D3 up-regulated protein 1 mediates oxidative stress via suppressing the thioredoxin function. J Immunol 164:6287–6295
    PubMed CAS Google Scholar
39. Schulze PC, Yoshioka J, Takahashi T, He Z, King GL, Lee RT (2004) Hyperglycemia promotes oxidative stress through inhibition of thioredoxin function by thioredoxin-interacting protein. J Biol Chem 279:30369–30374
    Article PubMed CAS Google Scholar
40. Yoshioka J, Schulze PC, Cupesi M, Sylvan JD, MacGillivray C, Gannon J, Huang H, Lee RT (2004) Thioredoxin-interacting protein controls cardiac hypertrophy through regulation of thioredoxin activity. Circulation 109:2581–2586
    Article PubMed CAS Google Scholar
41. Yamawaki H, Pan S, Lee RT, Berk BC (2005) Fluid shear stress inhibits vascular inflammation by decreasing thioredoxin-interacting protein in endothelial cells. J Clin Invest 115:733–738
    Article PubMed CAS Google Scholar
42. Yamawaki H, Lehoux S, Berk BC (2003) Chronic physiological shear stress inhibits tumor necrosis factor-induced proinflammatory responses in rabbit aorta perfused ex vivo. Circulation 108:1619–1625
    Article PubMed CAS Google Scholar
43. Butler LM, Zhou X, Xu WS, Scher HI, Rifkind RA, Marks PA, Richon VM (2002) The histone deacetylase inhibitor SAHA arrests cancer cell growth, up-regulates thioredoxin-binding protein-2, and down-regulates thioredoxin. Proc Natl Acad Sci USA 99:11700–11705
    Article PubMed CAS Google Scholar
44. Cheng GC, Schulze PC, Lee RT, Sylvan J, Zetter BR, Huang H (2004) Oxidative stress and thioredoxin-interacting protein promote intravasation of melanoma cells. Exp Cell Res 300:297–307
    Article PubMed CAS Google Scholar
45. Minn AH, Hafele C, Shalev A (2005) Thioredoxin-interacting protein is stimulated by glucose through a carbohydrate response element and induces beta-cell apoptosis. Endocrinology 146:2397–2405
    Article PubMed CAS Google Scholar
46. Wang Z, Rong YP, Malone MH, Davis MC, Zhong F, Distelhorst CW (2006) Thioredoxin-interacting protein (txnip) is a glucocorticoid-regulated primary response gene involved in mediating glucocorticoid-induced apoptosis. Oncogene 25:1903–1913
    Article PubMed CAS Google Scholar
47. Saitoh T, Tanaka S, Koike T (2001) Rapid induction and Ca2+ influx-mediated suppression of vitamin D3 up-regulated protein 1 (VDUP1) mRNA in cerebellar granule neurons undergoing apoptosis. J Neurochem 78:1267–1276
    Article PubMed CAS Google Scholar
48. Wang Y, De Keulenaer GW, Lee RT (2002) Vitamin D(3)-up-regulated protein-1 is a stress-responsive gene that regulates cardiomyocyte viability through interaction with thioredoxin. J Biol Chem 277:26496–26500
    Article PubMed CAS Google Scholar
49. Minn AH, Pise-Masison CA, Radonovich M, Brady JN, Wang P, Kendziorski C, Shalev A (2005) Gene expression profiling in INS-1 cells overexpressing thioredoxin-interacting protein. Biochem Biophys Res Commun 336:770–778
    Article PubMed CAS Google Scholar
50. Xiang G, Seki T, Schuster MD, Witkowski P, Boyle AJ, See F, Martens TP, Kocher A, Sondermeijer H, Krum H et al (2005) Catalytic degradation of vitamin D up-regulated protein 1 mRNA enhances cardiomyocyte survival and prevents left ventricular remodeling after myocardial ischemia. J Biol Chem 280:39394–39402
    Article PubMed CAS Google Scholar
51. Dutta KK, Nishinaka Y, Masutani H, Akatsuka S, Aung TT, Shirase T, Lee WH, Yamada Y, Hiai H, Yodoi J et al (2005) Two distinct mechanisms for loss of thioredoxin-binding protein-2 in oxidative stress-induced renal carcinogenesis. Lab Invest 85:798–807
    Article PubMed CAS Google Scholar
52. Han SH, Jeon JH, Ju HR, Jung U, Kim KY, Yoo HS, Lee YH, Song KS, Hwang HM, Na YS et al (2003) VDUP1 upregulated by TGF-beta1 and 1,25-dihydorxyvitamin D3 inhibits tumor cell growth by blocking cell-cycle progression. Oncogene 22:4035–4046
    Article PubMed CAS Google Scholar
53. Jeon JH, Lee KN, Hwang CY, Kwon KS, You KH, Choi I (2005) Tumor suppressor VDUP1 increases p27(kip1) stability by inhibiting JAB1. Cancer Res 65:4485–4489
    Article PubMed CAS Google Scholar
54. Nishinaka Y, Nishiyama A, Masutani H, Oka S, Ahsan KM, Nakayama Y, Ishii Y, Nakamura H, Maeda M, Yodoi J (2004) Loss of thioredoxin-binding protein-2/vitamin D3 up-regulated protein 1 in human T-cell leukemia virus type I-dependent T-cell transformation: implications for adult T-cell leukemia leukemogenesis. Cancer Res 64:1287–1292
    Article PubMed CAS Google Scholar
55. Nishinaka Y, Masutani H, Oka S, Matsuo Y, Yamaguchi Y, Nishio K, Ishii Y, Yodoi J (2004) Importin alpha1 (Rch1) mediates nuclear translocation of thioredoxin-binding protein-2/vitamin D(3)-up-regulated protein 1. J Biol Chem 279:37559–37565
    Article PubMed CAS Google Scholar
56. Escrich E, Moral R, Garcia G, Costa I, Sanchez JA, Solanas M (2004) Identification of novel differentially expressed genes by the effect of a high-fat n-6 diet in experimental breast cancer. Mol Carcinog 40:73–78
    Article PubMed CAS Google Scholar
57. Ohta S, Lai EW, Pang AL, Brouwers FM, Chan WY, Eisenhofer G, de Krijger R, Ksinantova L, Breza J, Blazicek P et al (2005) Down-regulation of metastasis suppressor genes in malignant pheochromocytoma. Int J Cancer 114:139–143
    Article PubMed CAS Google Scholar
58. Mizuno K, Tokumasu A, Nakamura A, Hayashi Y, Kojima Y, Kohri K, Noce T (2006) Genes associated with the formation of germ cells from embryonic stem cells in cultures containing different glucose concentrations. Mol Reprod Dev 73:437–445
    Article PubMed CAS Google Scholar
59. Hui TY, Sheth SS, Diffley JM, Potter DW, Lusis AJ, Attie AD, Davis RA (2004) Mice lacking thioredoxin-interacting protein provide evidence linking cellular redox state to appropriate response to nutritional signals. J Biol Chem 279:24387–24393
    Article PubMed CAS Google Scholar

Download references