Flufenamic acid as an inducer of mitochondrial permeability transition (original) (raw)
References
Insel PA: Analgesic-antipyretic and antiinflammatory agents and drugs employed in the treatment of gout. In: J.G. Hardman, A.G. Gilman, L.E. Limbird (eds). Goodman & Gilman's The Pharmacological Basis of Therapeutics, 9th edn., McGraw-Hill, New York, 1996, pp 617–657 Google Scholar
Tokumitsu Y, Lee S, Ui M: In vitro effects of nonsteroidal antiinflammatory drugs on oxidative phosphorylation in rat liver mitochondria. Biochem Pharmacol 26: 2101–2106, 1977 Google Scholar
McDougall P, Markhan A, Cameron I, Sweetman AJ: The mechanism of inhibition of mitochondrial oxidative phosphorylation by the nonsteroidal anti-inflammatory agent diflunisal. Biochem Pharmacol 32: 2595–2598, 1983 Google Scholar
McDougall P, Markhan A, Cameron I, Sweetman AJ: Action of the nonsteroidal anti-inflammatory agent, flufemanic acid, on calcium movements in isolated mitochondria. Biochem Pharmacol 37: 1327–1330, 1988 Google Scholar
Mingatto FE, Santos AC, Uyemura SA, Jordani MC, Curti C: In vitro interaction of nonsteroidal anti-inflammatory drugs on oxidative phosphorylation of rat kidney mitochondria: Respiration and ATP synthesis. Arch Biochem Biophys 334: 303–308, 1996 Google Scholar
Uyemura SA, Santos AC, Mingatto FE, Jordani MC, Curti C: Diclofenac sodium and mefenamic acid: Potent inducers of the membrane permeability transition in renal cortex mitochondria. Arch Biochem Biophys 342: 231–235; 1997 Google Scholar
Pigoso AA, Uyemura SA, Santos AC, Rodrigues T, Mingatto FE, Curti C: Influence of nonsteroidal anti-inflammatory drugs on calcium efflux in isolated rat renal cortex mitochondria and aspects of the mechanisms involved. Int J Biochem Cell Biol 30: 961–965, 1998 Google Scholar
You K: Salicylate and mitochondrial injury in Reye's syndrome. Science 221: 163–165, 1983 Google Scholar
Trost LC, Lemasters JJ: The mitochondrial permeability transition: A new pathophysiological mechanism for Reye's syndrome and toxic liver injury. J Pharmacol Exp Ther 278: 1000–1005, 1996 Google Scholar
Hunter DR, Haworth RA: The Ca2+-induced membrane transition in mitochondria: transitional Ca2+ release. Arch Biochem Biophys 195: 468–477, 1979 Google Scholar
Zoratti M, Szabò I: The mitochondrial permeability transition. Biochim Biophys Acta 1241: 139–176, 1995, 1365: 200–206, 1998 Google Scholar
Kroemer G, Dallaporta B, Resche-Rigon M: The mitochondrial death/ life regulator in apoptosis and necrosis. Annu Rev Physiol 60: 619–642, 1998 Google Scholar
Costantini P, Chernyak BV, Petronilli V, Bernardi P: Modulation of the mitochondrial permeability transition pore by pyridine nucleotides and dithiol oxidation at two separate sites. J Biol Chem 271: 6746–6751, 1996 Google Scholar
Lehninger AL, Vercesi AE, Bababunmi EA: Regulation of Ca2+ release from mitochondria by the oxidation-reduction state of pyridine nucleotides. Proc Natl Acad Sci (USA) 75: 1690–1694, 1978 Google Scholar
Weis M, Kass Gen, Orrenius S, Moldé us P: _N_-acetyl-_p_-benzoquinone imine induces Ca2+ release from mitochondria by stimulating pyridine nucleotide hydrolysis. J Biol Chem 267: 804–809, 1992 Google Scholar
Castilho RF, Kowaltowski AJ, Meinicke AR, Bechara EJH, Vercesi AE: Permeabilization of the inner mitochondrial membrane by Ca2+ ions is stimulated by _t_-butyl hydroperoxide and mediated by reactive oxygen species generated by mitochondria. Free Radic Biol Med 18: 479–486, 1995 Google Scholar
Kowaltowski AJ, Castilho RF, Vercesi AE: Opening of mitochondrial permeability transition pore by uncoupling or inorganic phosphate in the presence of Ca2+ is dependent on mitochondrial-generated reactive oxygen species. FEBS Lett 378: 150–152, 1996 Google Scholar
Petronilli V, Costantini P, Scorrano L, Colonna R, Passamonti S, Bernardi P: The voltage sensor of the mitochondrial permeability transition pore is turned by the oxidation-reduction state of vicinal thiols. Increase of the gating potential by oxidants and its reversal by reducing agents. J Biol Chem 269: 16638–16642, 1994 Google Scholar
Lemasters JJ, Nieminen AL, Qian T, Trost LC, Elmore SP, Nishimura Y, Crowe RA, Cascio WE, Bradham DA, Brenner DA, Herman B: The mitochondrial permeability transition in cell death: a common mechanism in necrosis, apoptosis and autophagy. Biochim Biophys Acta 1366: 171–196, 1998 Google Scholar
Pedersen PL, Greenawalt JW, Reynafarje B, Hullihen J, Decker GL, Soper JW, Bustamente E: Preparation and characterization of mitochondria and submitochondrial particles of rat liver and liverderived tissues. Meth Cell Biol 20: 411–481, 1978 Google Scholar
Cain K, Skilleter DN: Preparation and use of mitochondria in toxicological research. In: K. Snell, B. Mullock (eds). Biochemical Toxicology. IRL Press, Oxford, 1987, pp 217–254 Google Scholar
Emaus RK, Grunwald R, Lemasters JJ: Rhodamine 123 as a probe of transmembrane potential in isolated rat-liver mitochondria: Spectral and metabolic properties. Biochim Biophys Acta 850: 436–448, 1986 Google Scholar
Scarpa A: Measurements of cation transport with metallochromic indicators. In: S. Fleischer, L. Parcker (eds). Methods in Enzymology. Academic Press, New York, 1979, vol. 56, pp 301–352 Google Scholar
Cathcart R, Schwiers E, Ames BN: Detection of picomole levels of hydroperoxides using a fluorescent dichlorofluorescein assay. Anal Biochem 134: 111–116, 1983 Google Scholar
Jocelyn PC: Spectrophotometric assay of thiols. In: W.B. Jacoby, O.W. Griffith (eds). Methods in Enzymology. Academic Press, New York, 1987, vol. 143, pp 44–67 Google Scholar
Terada H: The interaction of highly active uncouplers with mitochondria. Biochim Biophys Acta 639: 225–242, 1981 Google Scholar
Canton M, Gennari F, Luvisetto S, Azzone GF: The nature of uncoupling by _n_-hexane, 1-hexanethiol and 1-hexanol in rat liver mitochondria. Biochim Biophys Acta 1274: 39–47, 1996 Google Scholar
Pfeiffer DR, Palmer JW, Beatrice MC, Stiers DL: The mechanism and regulation of Ca2+ efflux from mitochondria. In: D.F.L. Lenon, F.W. Stratman, R.N. Zahten (eds). Biochemical Metabolism Process. Elsevier/North-Holland, New York, 1983, pp 67–80 Google Scholar
Barbato F, La Rotonda MI, Quaglia F: Interactions of nonsteroidal antiinflammatory drugs with phospholipids: Comparison between octanol/buffer partition coefficients and chromatographic indexes on immobilized artificial membranes. J Pharmacol Sci 86: 225–229, 1997 Google Scholar
Broekemeier KM; Pfeiffer DR: Inhibition of the mitochondrial permeability transition by cyclosporin A during long time frame experiments: Relationship between pore opening and activity of mitochondrial phospholipases. Biochemistry 34: 16440–16449, 1995 Google Scholar
Bernardi P: The permeability transition pore. Control points of a cyclosporin A-sensitive mitochondrial channel involved in cell death. Biochim Biophys Acta 1275: 5–9, 1996 Google Scholar
Kowaltowski AJ, Naia-da-Silva ES, Castilho RF, Vercesi AE: Ca2+-stimulated mitochondrial reactive oxygen species generation and permeability transition are inhibited by dibucaine or Mg2+. Arch Biochem Biophys 359: 77–81, 1998 Google Scholar
Halestrap AP, Woodfield KY, Connern CP: Oxidative stress, thiol reagents, and membrane potential modulate the mitochondrial permeability transition by affecting nucleotide binding to the adenine nucleotide translocase. J Biol Chem 272: 3346–3354, 1997 Google Scholar