Influence of Postweaning Social Isolation in the Rat on Brain Development, Conditioned Behavior, and Neurotransmission (original) (raw)
REFERENCES
J. Altman and G. D. Das, “Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in the rat.” J. Comp. Neurol., No. 124, 319–336 (1965). Google Scholar
C. Beaulieu and M. Colonnier, “Richness of environment affects the number of contacts formed by buotons containing flat vesicles but does not alter the number of these boutons per neuron,” J. Comp. Neurol., No. 274, 347–356 (1988). Google Scholar
M. J. Bickerdicke, I. K. Wright, and C. A. Marsden, “Social isolation attenuates rat forebrain 5-HT release induced by KCl stimulation and exposure to a novel environment,” Behav. Pharmacol., No. 4, 231–236 (1993). Google Scholar
M. E. Bitterman, “The evolution of intelligence,” Scientific American, No. 212, 92–100 (1965). Google Scholar
S. L. Bowling, J. K. Rowlett, and M. T. Bardo, “The effect of environmental enrichment on amphetamine-stimulated locomotor activity, dopamine synthesis and dopamine release,” Neuropharmacology, No. 32, 885–893. (1993). Google Scholar
D. L. Braff and M. A. Geyer, “Sensorimotor gating and schizophrenia: human and animal model studies,” Arch. Gen. Psychiatry, No. 47, 181–188 (1990). Google Scholar
D. L. Braff, C. Grillon, and M. A. Geyer, “Gating and habituation of the startle reflex in schizophrenic patients,” Arch. Gen. Psychiatry, No. 49, 206–215 (1992). Google Scholar
D. L. Braff, C. Stone, E. Callaway, M. A. Geyer, I. D. Glick, and L. Bali, “Prestimulus effects of human startle reflex in normals and schizophrenics,” Psychophysiol., No. 15, 339–343 (1978). Google Scholar
A. K. Cadogan, D. A. Kendall, and C. A. Marsden, “Serotonin 5-HT(1A) receptor activation increases cyclic AMP formation in the rat hippocampus in vivo,” J. Neurochem., No. 62, 1816–1821 (1994). Google Scholar
J. T. Coyle and D. Henry, “Catecholamines in foetal and newborn rat brain,” J. Neurochem., No. 21, 61–67. 1973. Google Scholar
M. C. Diamond, “Extensive cortical depth measurements and neuronal size increases in the cortex of environmental enriched rats,” J. Comp. Neurol., No. 131, 357–364 (1967). Google Scholar
M. C. Diamond, F. Law, H. Rhodes, B. Lindner, M. R. Rosenzweig, D. Krech, and E. L. Bennett, “Increases in cortical depth and glia number in rats subjected to rich environment,” J. Comp. Neurol., No. 128, 117–126 (1966). Google Scholar
M. C. Diamond, B. Linder, R. Johnson, E. L. Bennett, and M. R. Rosenzweig, “Differences in occipital cortical synapses from environmentally enriched, impoverished and standard colony rats,” J Neurosci. Res., No. 1, 109–119 (1975). Google Scholar
L. P. Dwoskin, G. A. Gerhardt, C. J. Drebing, C. C. Wilcox, and N. R. Zahniser, “Uptake and release of dopamine from rat striatal slices: Comparison of PCP, amphetamine and nomifensine,” in: P. M. Beart, G. N. Woodruff, and D. M. Jackson (eds.), Pharmacology and Functional Regulation of Dopamine Neurons (1988).
S. L. Eastwood and P. J. Harrison, “Detection and quantification of hippocampal synaptophysin messenger RNA in schizophrenia using autoclaves, formalin-fixed, paraffin wax-embedded sections,” Neuroscience, No. 93, 99–106 (1999). Google Scholar
S. L. Eastwood, P. W. J. Burnet, and P. J. Harrison, “Altered synaptophysin expression as a marker of synaptic pathology in schizophrenia,” Neuroscience, No. 66, 309–319 (1995). Google Scholar
D. Einon and B. J. Sahakian, “Environmentally induced differences in susceptibility of rats to CNS stimulants and CNS depressants: evidence against a unitary explanation,” Psychopharmacology, No. 61, 299–307 (1979). Google Scholar
D. F. Einon, “Spatial memory and response strategies in rats: age, sex and rearing differences in performance,” Quart. J. Exper. Psychol., No. 32, 473–489 (1980). Google Scholar
D. F. Einon, A. P. Humphreys, S. M. Chivers, S. Field, and V. Naylor, “Isolation has permanent effects upon the behavior of the rat, but not the mouse, gerbil or guinea pig,” Dev. Psychobiol., No. 14, 343–355 (1980). Google Scholar
D. F. Einon and M. J. Morgan, “A critical period for social isolation in the rat,” Dev. Psychobiol., No. 10, 123–132 (1977). Google Scholar
B. F. M. Fiala, F. M. Snow, and W. T. Greenough, “'Impoverished' rats weigh more than 'enriched' rats because they eat more,” Dev. Psychobiol., No. 10, 537–541 (1977). Google Scholar
M. K. Floeter and W. T. Greenough, “Cerebellar plasticity: modification of Purkinje cell structure by differential rearing in monkeys,” Science, No. 206, 227–229 (1979). Google Scholar
K. C. F. Fone, K. Shalders, Z. D. Fox, R. Arthur, and C. A. Marsden, “Increased 5-HT2C receptor responsiveness occurs on rearing rats in social isolation,” Psychopharmacology, No. 123, 346–352 (1996). Google Scholar
A. J. Fulford, S. Butler, D. J. Heal, D. A. Kendall, and C. A. Marsden, “Evidence of altered α2-adrenoceptor function following isolation-rearing in the rat,” Psychopharmacology, No. 116, 183–190 (1994). Google Scholar
A. J. Fulford and C. A. Marsden, “Conditioned release of 5-hydroxytryptamine in vivo in the nucleus accumbens following isolation-rearing in the rat,” Neuroscience, No. 83, 481–487 (1997). Google Scholar
A. J. Fulford and C. A. Marsden, “Effect of isolation-rearing on conditioned dopamine release in vivo in the nucleus accumbens of the rat,” J. Neurochem., No. 70, 384–390 (1998). Google Scholar
A. J. Fulford and C. A. Marsden, “Effect of isolation-rearing on noradrenaline release in rat hypothalamus and hippocampus in vitro,” Brain Res., No. 748, 93–99 (1997). Google Scholar
A. J. Fulford and C. A. Marsden, “Social isolation in the rat enhances α2-autoreceptor function in the hippocampus in vivo,” Neuroscience, No. 77, 57–64 (1997). Google Scholar
C. Gentsch, M. Lichtsteiner, and H. Feer, “Locomotor activity, defecation score and corticosterone levels during open-field exposure: a comparison among individually and group-housed rats and genetically selected rat lines,” Physiol. Behav., No. 27, 183–186 (1981). Google Scholar
C. Gentsch, M. Lichtsteiner, K. Kraeuchi, and H. Feer, “Different reaction patterns in individually and socially reared rats during exposure to novel environments,” Behav. Brain Res., No. 4, 45–54 (1982). Google Scholar
M. A. Geyer, N. R. Swerdlow, R. S. Mansbach, and D. L. Braff, “Startle response models of sensorimotor gating and habituation deficits in schizophrenia,” Brain Res. Byull., No. 25, 485–498 (1990). Google Scholar
M. A. Geyer, L. S. Wilkinson, T. Humby, and T. W. Robbins, “Isolation rearing of rats produces a deficit in prepulse inhibition of acoustic startle similar to that in schizophrenia,” Biol. Psychiatry, No. 34, 361–372 (1993). Google Scholar
A. Globus, M. R. Rosenzweig, E. L. Bennett, and M. Diamond, “Effects of differential experience on dendritic spine counts in rat cerebral cortex,” J. Comp. Physiol. Psychol., No. 82, 175–181 (1973). Google Scholar
C. Grillon, R. Ameli, D. S. Charney, J. Krystal, and D. L. Braff, “Startle gating deficits occur across prepulse intensities in schizophrenic patients,” Biol. Psychiatry, No. 32, 939–943 (1992). Google Scholar
F. S. Hall, T. Humby, L. S. Wilkinson, and T. W. Robbins, “The effects of isolation-rearing of rats on behavioral responses to food and environmental novelty,” Physiol. Behav., No. 62, 281–290 (1997). Google Scholar
F. S. Hall, L. S. Wilkinson, T. Humby, W. Inglis, D. A. Kendall, C. A. Marsden, and T. W. Robbins, “Isolation rearing in rats: pre-and postsynaptic changes in striatal dopaminergic systems,” Pharmacol. Biochem. Behav., No. 59, 859–872 (1998). Google Scholar
C. J. Harmer and G. D. Phillips, “Isolation rearing enhances acquisition in a conditioned inhibition paradigm,” Physiol Behav., No. 65, 525–533 (1998). Google Scholar
C. J. Harmer and G. D. Phillips, “Isolation rearing enhances the rate of acquisition of a discriminative approach task but does not affect the efficacy of conditioned reward,” Physiol. Behav., No. 63, 177–184 (1998). Google Scholar
A. Hatch, G. S. Wiberg, T. Balazs, and H. C. Grice, “Long-term isolation stress in rats,” Science, No. 208, 507 (1963). Google Scholar
D. O. Hebb, “The effects of early experience on problem solving at maturity,” Am. Psychol., No. 2, 306–307 (1947). Google Scholar
P. K. Hitchcott, C. M. T. Bonardi, and G. D. Phillips, “Enhanced stimulus-reward learning by intra-amygdala administration of D3 dopamine receptor agonist,” Psychopharmacology (Berlin), No. 133, 240–248 (1997). Google Scholar
P. K. Hitchott, C. J. Harmer, and G. D. Phillips, “Enhanced acquisition of discriminative approach following intra-amygdala amphetamine,” Psychopharmacology (Berlin), No. 132, 237–246 (1997). Google Scholar
R. R. Holson, “Feeding neophobia: A possible explanation for the differential maze performance of rats reared in enriched or isolated environments,” Physiol. Behav., No. 38, 191–201 (1986). Google Scholar
R. R. Holson, A. C. Scallet, S. F. Ali, and B. B. Turner, “'Isolation stress' revisited: isolation rearing effects depend on animal care methods,” Physiol. Behav., No. 49, 1107–1118 (1991). Google Scholar
K. Hori, J. Tanaka, and M. Nomura, “Effects of discrimination learning on the rat amygdala release: a microdialysis study,” Brain Res., No. 621, 296–300 (1993). Google Scholar
M. Ichikawa, M. Matsuoka, and Y. Mori, “Effect of differential rearing on synapses and soma size in rat amygdaloid nucleus,” Synapse, No. 13, 50–56 (1993). Google Scholar
G. H. Jones, T. D. Hernandez, D. A. Kendall, C. A. Marsden, and T. W. Robbins, “Dopaminergic and serotonergic function following isolation rearing in rats. a study of behavioral responses and postmortem and in vivo neurochemistry,” Pharmacol. Biochem. Behav., No. 43, 17–35 (1992). Google Scholar
G. H. Jones, C. A. Marsden, and T. W. Robbins, “Increased sensitivity to amphetamine and reward-related stimuli following social isolation in rats: possible disruption of dopamine-dependent mechanisms of the nucleus accumbens,” Psychopharmacology, No. 102, 364–372 (1990). Google Scholar
G. H. Jones, C. A. Marsden, and T. W. Robbins, “Behavioral rigidity and rule-learning deficits following isolation-reaing in the rat: neurochemical correlates,” Behav. Brain Res., No. 43, 35–50 (1991). Google Scholar
G. H. Jones, T. W. Robbins, and C. A. Marsden, “Isolation-rearing retards the acquisition of schedule-induced polydipsia in rats,” Physiol. Behav., No. 45, 71–77 (1989). Google Scholar
J. N. Joyce, “The dopamine hypothesis of schizophrenia: limbic interaction with serotonin and norepinephrine,” Psychopharmacology, No. 112, S16–S34 (1993). Google Scholar
J. M. Juraska, C. Henderson, and J. Muller, “Differential rearing experience, gender and radial maze performance,” Dev. Psychobiol., No. 17, 209–215 (1984). Google Scholar
M. S. Kaplan and D. H. Bell, “Neuronal proliferation in the 9-month-old rodent - radioautographic study of granule cells in the hippocampus,” Exp. Brain Res., No. 52, 1–5 (1983). Google Scholar
M. S. Kaplan and D. H. Bell, “Mitotic neuroblasts in the 9-day-old and 11-month-old rodent hippocampus,” J. Neurosci., No. 4, 1429–1441 (1984). Google Scholar
M. S. Kaplan and J. W. Hinds, “Neurogenesis in the adult rat: electron microscopic analysis of the light radioautographs,” Science, No. 197, 1092–1094 (1977). Google Scholar
N. Karki, R. Kuntzman, and B. B. Brodie, “Norepinephrine and serotonin brain levels at various stages of ontogenic development,” Fed. Proc., No. 19, 282 (1960). Google Scholar
K. Konrad and R. Melzack, “Novelty-enhancement effects associated with early sensorisocial isolation,” Psychol. Byull., No. 82, 986–995 (1975). Google Scholar
G. W. Kraemer, M. H. Ebert, C. R. Lake, and W. T. McKinney, “Hypersensitivity to d-amphetamine several years after early social deprivation in rhesus monkeys,” Psychopharmacology, No. 82, 266–271 (1984). Google Scholar
G. W. Kraemer and W. T. McKinney, “Social separation increases alcohol consumption in rhesus monkeys,” Psychopharmacology, No. 86, 182–189 (1985). Google Scholar
D. Krech, M. R. Rosenzweig, and E. L. Bennett, “Relations between brain chemistry and problem-solving among rats raised in enriched and impoverished environments,” J. Comp. Physiol. Psychol., No. 55, 801–807 (1962). Google Scholar
L. P. Lanier and R. L. Issacson, “Early developmental changes in the locomotor response to amphetamine and their relation to hippocampal function,” Brain Res., No. 126, 567–575 (1977). Google Scholar
M. D. S. Lapiz, Y. Mateo, T. L. Parker, and C. A. Marsden, “Central noradrenergic depletion enhanced hole-poking behavior in isolated rats,” Soc. Neurosci. Abstr., No. 25(2), 1876 (1999). Google Scholar
M. D. S. Lapiz, Y. Mateo, S. Durkin, S. Muchimapura, T. L. Parker, and C. A. Marsden, “Central noradrenergic depletion in isolated rats enhances retention but not acquisition in the water maze,” Behav. Pharmacol (Suppl.), No. 10, S55 (1999). Google Scholar
M. D. S. Lapiz, Y. Mateo, and C. A. Marsden, “Effects of noradrenaline depletion in the brain on response to novelty in isolation reared rats,” Psychopharmacology (submitted) (2000).
M. D. S. Lapiz, Y. Mateo, T. L. Parker, and C. A. Marsden, “Noradrenergic involvement in the exploratory behavior of isolation reared rats,” Br. J. Pharmacol. (Suppl.), No. 63 (in press) (2000).
M. D. S. Lapiz, T. L. Parker, and C. A. Marsden, “Changes in phencyclidine-induced behavior following isolation rearing in the rat,” Br. J. Pharmacol. (Suppl.), No. 128, 201P (1999).
M. D. S. Lapiz, T. L. Parker, and C. A. Marsden, “Effects of acute and subchronic phencyclidine administration on the locomotor behavior of isolation-reared rats,” J. Psychopharmacol. (Suppl. A), No. 13, A12 (1999). Google Scholar
M. D. S. Lapiz, T. L. Parker, and C. A. Marsden, “Social isolation affects response to novelty and to _d_-amphetamine,” Proc. Aust. Neurosci. Soc., No. 10, 200 (1999). Google Scholar
L. J. Martin, D. M. Spicer, M. H. Lewis, J. P. Gluck, and L. C. Cork, “Social deprivation in infact rhesus monkeys alters the chemoarchitecture of the brain: I. Subcortical regions,” J Neurosci., No. 11, 3344–3358 (1991). Google Scholar
E. Masliah, R. D. Terry, M. Alford, and R. DeTeresa, “Quantitative immunohistochemistry of synaptophysin in human neocortex: an alternative method to estimate density of presynaptic terminals in paraffin sections,” J. Histochem. Cytochem., No. 38, 837–844 (1990). Google Scholar
W. A. Mason, R. K. Davenport, and E. W. Menzel, “Early experience and the social development of rhesus monkeys and chimpanzees,” in: Newton G., Levine S. (eds.), Early Experience and Behavior, Thomas, Springfield, Illinois (1968). Google Scholar
M. J. Morgan, “Effects of post-weaning environment on learning in the rat,” Anim. Behav., No. 21, 429–442 (1973). Google Scholar
M. Morgan and D. Einon, “Incentive motivation and behavioral inhibition in socially-isolated rats,” Physiol. Behav., No. 15, 405–409 (1975). Google Scholar
A. Morinan and V. Parker, “Are socially isolated rats anxious?” Br. J. Pharmacol., No. 86, 460 (1986). Google Scholar
J. H. Morrison, P. R. Hof, W. Janssen, J. L. Bassett, S. L. Foote, G. W. Kraemer, and W. T. McKinney, “Quantitative neuroanatomic analyses of cerebral cortex in rhesus monkey from different rearing conditions,” Proc. Soc. Neurosci., No. 16, 789, P12 (1990). Google Scholar
S. Muchimapura, R. Mason, and C. A. Marsden, “Effect of social isolation on hippocampal 5-HT1A receptor activity in the Lister Hooded rat,” Br. J. Pharmacol (Suppl.), No. 128, 203 (1999). Google Scholar
S. Muchimapura, R. Mason, and C. A. Marsden, “Effects of social isolation on hippocampal neuronal activity in vitro,” J. Psychopharmacology (Suppl.), No. 13 (1999).
J. C. Neill and B. Costall, “The effect of isolation rearing on ethanol and saccharin preference in the rat,” J. Psychopharmacology (Suppl.), No. 10(3), A10 (1996). Google Scholar
M. G. Packard, L. Cahill, and J. L. McGaugh, “Amydala modulation of hippocampal-dependent and caudate nucleus-dependent memory processes,” Proc. Nat. Acad. Sci. USA, No. 91, 8477–8481 (1994). Google Scholar
G. D. Phillips, S. R. Howes, R. B. Whitelaw, L. S. Wilkinson, and T. W. Robbins, “Isolation rearing enhances the locomotor response to cocaine and a novel environment, but impairs the intravenous administration of cocaine,” Psychopharmacology, No. 115, 407–418 (1994) Google Scholar
G. P. Sackett, “Prospects for research on schizophrenia. 3. Neurophysiology. Isolation rearing in primates,” Neurosci. Res. Prog. Byull., No. 10, 388–390 (1972). Google Scholar
B. J. Sahakian and T. W. Robbins, “Isolation-rearing enhances tail pinch-induced oral behavior in rats,” Physiol. Behav., No. 18, 53–58 (1977). Google Scholar
B. J. Sahakian, T. W. Robbins, and S. D. Iversen, “The effects of isolation rearing on exploration in the rat,” Anim. Learn. Behav., No. 5, 193–198 (1977). Google Scholar
B. J. Sahakian, T. W. Robbins, M. J. Morgan, and S. D. Iversen, “The effects of psychomotor stimulants on stereotypy and locomotor activity in socially-deprived and control rats,” Brain Res., No. 84, 195–205 (1975). Google Scholar
P. F. D. Seitz, “Infantile experience and adult behavior in animal subjects. II. Age of separation from the mother and adult behavour in the cat,” Psychosom. Med., No. 21, 353–378 (1959). Google Scholar
B. V. J. Siegel, M. S. Buchsbaum, W. E. J. Bunney, L. A. Gottschalk, R. J. Haier, J. B. Lohr, S. Lottenberg, A. Najafi, K. H. Neuchterlein, S. G. Potkin, and J. C. Wu, “Cortico-striatal thalamic circuits and brain glucose metabolic activity in 70 unmedicated male schizophrenic patients,” Am. J. Psychiatry, No. 150, 1325–1336 (1993). Google Scholar
A. M. Sirevaag and W. T. Greenough, “Differential rearing effects on rat visual cortex synapses. III. Neuronal and glial nuclei, buotons, dendrites, and capillaries,” Brain Res., No. 424, 320–332 (1987). Google Scholar
J. K. Smith, J. C. Neill, and B. Costall, “Post-weaning housing conditions influence the behavioral effects of cocaine and d-amphetamine,” Psychopharmacology, No. 131, 23–33 (1997). Google Scholar
S. C. Stanford, V. Parker, and A. Morinan, “Deficits in exploratory behavior in socially-isolated rats are not accompanied by changes in cerebral cortical adrenoceptor binding,” J. Aff. Dis., No. 15, 175–180 (1988). Google Scholar
N. R. Swerdlow, S. B. Caine, D. L. Braff, and M. A. Geyer, “The neural substrates of sensorimotor gating of the startle reflex: a review of recent findings and their implications,” J. Psychopharmacol., No. 6, 176–190 (1992). Google Scholar
L. A. Syme, “Social isolation at weaning, some effects on two measures of activity,” Anim. Learn. Behav., No. 1, 161–163 (1973). Google Scholar
N. B. Thoa, Y. Tizabi, and D. M. Jacobowitz, “The effect of prolonged isolation on the catecholamine and serotonin concentrations of discrete areas of the rat brain,” in: E. Usdin, R. Kvetnansky, and I. J. Kopin (eds.), Catecholamines and Stress, Pergamon Press, Oxford (1976) pp.61–66. Google Scholar
N. B. Thoa, Y. Tizabi, and D. M. Jacobowitz, “The effects of isolation on catecholamine concentration and turnover in discrete areas of the rat brain,” Brain Res., No. 131, 259–269 (1977). Google Scholar
L. Valzelli, “The isolation syndrome in mice,” Psychopharmacology, No. 31, 305–320 (1973). Google Scholar
G. B. Varty, C. A. Marsden, and G. A. Higgins, “Reduced synaptophysin immunoreactivity in the dentate gyrus of prepulse inhibition-impaired isolation-reared rats,” Brain Res., No. 824, 197–203 (1999). Google Scholar
F. R. Volkmar and W. T. Greenough, “Rearing complexity affects branching of dendrites in the visual cortical synapses of rats: preliminary results,” Behav. Biol., No. 7, 279–284 (1972). Google Scholar
I. C. Weiss, J. Feldon, and A. M. Domeney, “Isolation rearing-induced disruption of prepulse inhibition: Further evidence for fragility of the response,” Behav. Pharmacol., No. 10, 139–149 (1999). Google Scholar
L. S. Wilkinson, S. S. Killcross, T. Humby, F. S. Hall, M. A. Geyer, and T. W. Robbins, “Social isolation in the rat produces developmentally specific deficits in prepulse inhibition of the acoustic startle response without disrupting latent inhibition,” Neuropsychopharmacology, No. 10, 63–72 (1994). Google Scholar
B. E. Will, M. R. Rosenzweig, and E. L. Bennett, “Effects of differential environments on recovery from neonatal brain lesions, measured by problem-solving scores and brain dimensions,” Physiol. Behav., No. 16, 603–611 (1976). Google Scholar
P. Willner, “The validity of animal models of depression,” Psychopharmacology, No. 83, 1–16 (1984). Google Scholar
C. A. Wilmot, C. VanderWende, and M. T. Spoerlein, “Behavioral and biochemical studies of dopamine receptor sensitivity in differentially housed mice,” Psychopharmacology, No. 89, 364–369 (1986). Google Scholar
N. Wongwitdecha and C. A. Marsden, “Effect of social isolation on the reinforcing properties of morphine in the conditioned place preference test,” Pharmacol. Biochem. Behav., No. 53, 531–534 (1996). Google Scholar
N. Wongwitdecha and C. A. Marsden, “Effects of social isolation on learning in the Morris water maze,” Brain Res., No. 715, 119–124 (1996). Google Scholar
N. Wongwitdecha and C. A. Marsden, “Social isolation increases aggressive behavior and alters the effects of diazepam in the rat social interaction test,” Behav. Brain Res., No. 75, 27–32 (1996). Google Scholar
P. J. Woods, A. S. Fiske, and S. I. Ruckelshaus, “The effects of drives conflicting with exploration on the problem solving behavior of rats reared in free and restricted environments,” J. Comp. Physiol. Psychol., No. 54, 167–169 (1961). Google Scholar
I. K. Wright, H. Ismail, N. Upton, and C. A. Marsden, “Resocialization of isolation-reared rats do not alter their anxiogenic profile in the elevated X-maze model of anxiety,” Physiol. Behav., No. 50, 1129–1132 (1991). Google Scholar