A hydrogenosome with a genome (original) (raw)
- Scientific Correspondence
- Published: 10 December 1998
- Frank Voncken1,
- Theo van Alen1,
- Angela van Hoek1,
- Brigitte Boxma1,
- Godfried Vogels1,
- Marten Veenhuis2 &
- …
- Johannes H.P. Hackstein1
Nature volume 396, pages 527–528 (1998)Cite this article
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Abstract
Some anaerobic protozoa and chytridiomycete fungi possess membrane-bound organelles known as hydrogenosomes. Hydrogenosomes are about 1 micrometre in diameter and are so called because they produce molecular hydrogen1. It has been postulated that hydrogenosomes evolved from mitochondria by the concomitant loss of their respiration and organellar genomes1,4, and so far no hydrogenosome has been found that has a genome1,2. Here we provide evidence for the existence of a hydrogenosomal genome of mitochondrial descent, and show that the anaerobic heterotrichous ciliate Nyctotherus ovalis possesses a new type of nuclear-encoded ‘iron-only’ hydrogenase enzyme.
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Author notes
- Anna Akhmanova
Present address: Department of Cell Biology and Genetics, Erasmus University, NL-3000 DR, Rotterdam, The Netherlands
Authors and Affiliations
- Department of Microbiology and Evolutionary Biology, University of Nijmegen, Nijmegen, NL-6525 ED, The Netherlands
Anna Akhmanova, Frank Voncken, Theo van Alen, Angela van Hoek, Brigitte Boxma, Godfried Vogels & Johannes H.P. Hackstein - Department of Microbiology, University of Groningen, Haren, NL-9750 AA, The Netherlands
Marten Veenhuis
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- Anna Akhmanova
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Akhmanova, A., Voncken, F., van Alen, T. et al. A hydrogenosome with a genome.Nature 396, 527–528 (1998). https://doi.org/10.1038/25023
- Issue Date: 10 December 1998
- DOI: https://doi.org/10.1038/25023
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