A hydrogenosome with a genome (original) (raw)

Nature volume 396, pages 527–528 (1998)Cite this article

Abstract

Some anaerobic protozoa and chytridiomycete fungi possess membrane-bound organelles known as hydrogenosomes. Hydrogenosomes are about 1 micrometre in diameter and are so called because they produce molecular hydrogen1. It has been postulated that hydrogenosomes evolved from mitochondria by the concomitant loss of their respiration and organellar genomes1,4, and so far no hydrogenosome has been found that has a genome1,2. Here we provide evidence for the existence of a hydrogenosomal genome of mitochondrial descent, and show that the anaerobic heterotrichous ciliate Nyctotherus ovalis possesses a new type of nuclear-encoded ‘iron-only’ hydrogenase enzyme.

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Author notes

  1. Anna Akhmanova
    Present address: Department of Cell Biology and Genetics, Erasmus University, NL-3000 DR, Rotterdam, The Netherlands

Authors and Affiliations

  1. Department of Microbiology and Evolutionary Biology, University of Nijmegen, Nijmegen, NL-6525 ED, The Netherlands
    Anna Akhmanova, Frank Voncken, Theo van Alen, Angela van Hoek, Brigitte Boxma, Godfried Vogels & Johannes H.P. Hackstein
  2. Department of Microbiology, University of Groningen, Haren, NL-9750 AA, The Netherlands
    Marten Veenhuis

Authors

  1. Anna Akhmanova
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  2. Frank Voncken
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  3. Theo van Alen
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  4. Angela van Hoek
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  5. Brigitte Boxma
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  6. Godfried Vogels
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  7. Marten Veenhuis
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  8. Johannes H.P. Hackstein
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Akhmanova, A., Voncken, F., van Alen, T. et al. A hydrogenosome with a genome.Nature 396, 527–528 (1998). https://doi.org/10.1038/25023

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