Astromicin (original) (raw)

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Chemical compound

Pharmaceutical compound

Astromicin
Clinical data
AHFS/Drugs.com International Drug Names
Routes of administration IV
ATC code none
Legal status
Legal status In general: ℞ (Prescription only)
Identifiers
IUPAC name 2-Amino-N_-[(1_S,2_R_,3_R_,4_S_,5_S_,6_R_)-4-amino-3-[(2_R_,3_R_,6_S_)-3-amino-6-(1-aminoethyl)oxan-2-yl]oxy-2,5-dihydroxy-6-methoxycyclohexyl]-_N_-methylacetamide
CAS Number 55779-06-1 ☒N
PubChem CID 65345
ChemSpider 4447577 checkY
UNII 7JHD84H15J
KEGG D07470 checkY
ChEBI CHEBI:37923 ☒N
ChEMBL ChEMBL1909053 ☒N
CompTox Dashboard (EPA) DTXSID2022624 Edit this at Wikidata
Chemical and physical data
Formula C17H35N5O6
Molar mass 405.496 g·mol−1
3D model (JSmol) Interactive image
SMILES O=C(N(C)[C@@H]2[C@@H](OC)[C@@H](O)[C@H](N)[C@@H](O[C@H]1O[C@H]([C@@H](N)C)CC[C@H]1N)[C@@H]2O)CN
InChI InChI=1S/C17H35N5O6/c1-7(19)9-5-4-8(20)17(27-9)28-15-11(21)13(24)16(26-3)12(14(15)25)22(2)10(23)6-18/h7-9,11-17,24-25H,4-6,18-21H2,1-3H3/t7-,8+,9-,11-,12-,13-,14+,15+,16+,17+/m0/s1 checkYKey:BIDUPMYXGFNAEJ-APGVDKLISA-N checkY
☒NcheckY (what is this?) (verify)

Astromicin (INN; also frequently referenced in scientific journal articles as fortimicin A/B) is an aminoglycoside antibiotic. It is produced by Micromonospora olivasterospora (also named with additional o in olivoasterospora).[1][2]

  1. ^ Itoh S, Odakura Y, Kase H, Satoh S, Takahashi K, Iida T, Shirahata K, Nakayama K (December 1984). "Biosynthesis of astromicin and related antibiotics. I. Biosynthetic studies by bioconversion experiments". The Journal of Antibiotics. 37 (12): 1664–9. doi:10.7164/antibiotics.37.1664. PMID 6526734.
  2. ^ Odakura Y, Kase H, Itoh S, Satoh S, Takasawa S, Takahashi K, Shirahata K, Nakayama K (December 1984). "Biosynthesis of astromicin and related antibiotics. II. Biosynthetic studies with blocked mutants of Micromonospora olivasterospora". The Journal of Antibiotics. 37 (12): 1670–80. doi:10.7164/antibiotics.37.1670. PMID 6526735.