MYH7B (original) (raw)

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Protein-coding gene in the species Homo sapiens

MYH7B
Identifiers
Aliases MYH7B, MHC14, MYH14, myosin, heavy chain 7B, cardiac muscle, beta, myosin heavy chain 7B
External IDs OMIM: 609928; MGI: 3710243; HomoloGene: 66117; GeneCards: MYH7B; OMA:MYH7B - orthologs
Gene location (Human)Chromosome 20 (human)Chr.Chromosome 20 (human)[1]Chromosome 20 (human)Genomic location for MYH7BGenomic location for MYH7BBand20q11.22Start34,955,810 bp[1]End35,002,437 bp[1]
Gene location (Mouse)Chromosome 2 (mouse)Chr.Chromosome 2 (mouse)[2]Chromosome 2 (mouse)Genomic location for MYH7BGenomic location for MYH7BBand2|2 H1Start155,453,132 bp[2]End155,476,227 bp[2]
RNA expression patternBgeeHuman Mouse (ortholog)Top expressed inapex of heartmuscle of thighleft ventricleright auricleSkeletal muscle tissue of rectus abdominisbody of tonguebiceps brachiiSkeletal muscle tissue of biceps brachiilateral nuclear group of thalamusspermTop expressed invascular smooth musclelensneural layer of retinaleft ventriclesoleus musclevasculature of trunksuperior frontal gyruscerebellar cortexmyocardium of atriumprimary visual cortexMore reference expression dataBioGPSn/a
Gene ontologyMolecular function nucleotide binding actin binding cytoskeletal motor activity protein binding ATP binding actin filament binding microtubule motor activity microtubule binding Cellular component myosin filament membrane myosin complex cardiac myofibril Biological process microtubule-based movement Sources:Amigo / QuickGO
OrthologsSpeciesHuman MouseEntrez57644668940EnsemblENSG00000078814ENSMUSG00000074652UniProtQ5JW45A2AQP0RefSeq (mRNA)NM_020884NM_033424NM_001085378RefSeq (protein)NP_065935NP_001078847Location (UCSC)Chr 20: 34.96 – 35 MbChr 2: 155.45 – 155.48 MbPubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Myosin-7B also known as myosin, heavy chain 7B is a protein that in humans is encoded by the MYH7B gene.[5][6]

MYH7B is a slow-twitch myosin.[6]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000078814 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000074652 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Nagase T, Kikuno R, Ishikawa K, Hirosawa M, Ohara O (April 2000). "Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (2): 143–50. doi:10.1093/dnares/7.2.143. PMID 10819331.
  6. ^ a b Desjardins PR, Burkman JM, Shrager JB, Allmond LA, Stedman HH (April 2002). "Evolutionary implications of three novel members of the human sarcomeric myosin heavy chain gene family". Mol. Biol. Evol. 19 (4): 375–93. doi:10.1093/oxfordjournals.molbev.a004093. PMID 11919279.