RAI14 (original) (raw)

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Protein-coding gene in humans

RAI14
Identifiers
Aliases	RAI14, NORPEG, RAI13, retinoic acid induced 14
External IDs	OMIM: 606586; MGI: 1922896; HomoloGene: 9199; GeneCards: RAI14; OMA:RAI14 - orthologs
Gene location (Human)Chr.Chromosome 5 (human)[1]Band5p13.2Start34,656,328 bp[1]End34,832,612 bp[1]
Gene location (Mouse)Chr.Chromosome 15 (mouse)[2]Band15|15 A1Start10,569,055 bp[2]End10,714,710 bp[2]
RNA expression patternBgeeHuman Mouse (ortholog)Top expressed instromal cell of endometriumvisceral pleuraventricular zonesmooth muscle tissueplacentadeciduaglomerulusamniotic fluidmetanephric glomerulusmyometriumTop expressed inrenal corpusclelumbar spinal ganglionciliary bodyleft lung lobeirishair follicleendothelial cell of lymphatic vesseluretermaxillary prominencesciatic nerveMore reference expression dataBioGPSMore reference expression data
Gene ontologyMolecular function protein binding Cellular component cell cortex cytoskeleton nucleus fibrillar center cytoplasm cytosol cell junction Biological process spermatogenesis cell differentiation Sources:Amigo / QuickGO
OrthologsSpeciesHuman MouseEntrez2606475646EnsemblENSG00000039560ENSMUSG00000022246UniProtQ9P0K7Q9EP71RefSeq (mRNA)NM_001145520NM_001145521NM_001145522NM_001145523NM_001145525NM_015577NM_001166408NM_030690NM_001356534RefSeq (protein)NP_001138992NP_001138993NP_001138994NP_001138995NP_001138997NP_056392NP_001159880NP_109615NP_001343463Location (UCSC)Chr 5: 34.66 – 34.83 MbChr 15: 10.57 – 10.71 MbPubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Ankycorbin is a protein that in humans is encoded by the RAI14 gene.[5][6] Ankycorbin has been associated with the cortical actin cytoskeleton structures in terminal web, cell-cell adhesion sites as well as stress fibres.[7]

1. ^ a b c GRCh38: Ensembl release 89: ENSG00000039560 – Ensembl, May 2017
2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000022246 – Ensembl, May 2017
3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. ^ Kutty RK, Kutty G, Samuel W, Duncan T, Bridges CC, El-Sherbeeny A, Nagineni CN, Smith SB, Wiggert B (May 2001). "Molecular characterization and developmental expression of NORPEG, a novel gene induced by retinoic acid". J Biol Chem. 276 (4): 2831–40. doi:10.1074/jbc.M007421200. PMID 11042181.
6. ^ "Entrez Gene: RAI14 retinoic acid induced 14".
7. ^ Peng YF, Mandai K, Sakisaka T, Okabe N, Yamamoto Y, Yokoyama S, Mizoguchi A, Shiozaki H, Monden M, Takai Y (December 2000). "Ankycorbin: a novel actin cytoskeleton-associated protein". Genes Cells. 5 (12): 1001–8. doi:10.1046/j.1365-2443.2000.00381.x. PMID 11168586. S2CID 19149724.

• Jin J, Smith FD, Stark C, Wells CD, Fawcett JP, Kulkarni S, Metalnikov P, O'Donnell P, Taylor P, Taylor L, Zougman A, Woodgett JR, Langeberg LK, Scott JD, Pawson T (August 2004). "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization". Curr. Biol. 14 (16): 1436–50. Bibcode:2004CBio...14.1436J. doi:10.1016/j.cub.2004.07.051. PMID 15324660. S2CID 2371325.
• Yuan W, Zheng Y, Huo R, Lu L, Huang XY, Yin LL, Li JM, Zhou ZM, Sha JH (September 2005). "Expression of a novel alternative transcript of the novel retinal pigment epithelial cell gene NORPEG in human testes". Asian J. Androl. 7 (3): 277–88. doi:10.1111/j.1745-7262.2005.00040.x. PMID 16110356.
• Kutty RK, Chen S, Samuel W, Vijayasarathy C, Duncan T, Tsai JY, Fariss RN, Carper D, Jaworski C, Wiggert B (July 2006). "Cell density-dependent nuclear/cytoplasmic localization of NORPEG (RAI14) protein". Biochem. Biophys. Res. Commun. 345 (4): 1333–41. doi:10.1016/j.bbrc.2006.04.184. PMID 16729964.
• Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.