Rhc80267 (original) (raw)

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Rhc80267

Names
Preferred IUPAC name _N_′,_N_′′′-(Hexane-1,6-diyl)bis(_N_-cyclohexylidenehydroxylamine-_O_-carboxamide)
Other namesRHC 80267, RG 80267, U 57908
Identifiers
CAS Number 83654-05-1 checkY
3D model (JSmol) Interactive image
ChemSpider 4887 ☒N
IUPHAR/BPS 5255
MeSH 1,6-bis(cyclohexyloximinocarbonyl)hexane
PubChem CID 5063
UNII 9VB68H5WIT checkY
CompTox Dashboard (EPA) DTXSID90232494 Edit this at Wikidata
InChI InChI=1S/C20H34N4O4/c25-19(27-23-17-11-5-3-6-12-17)21-15-9-1-2-10-16-22-20(26)28-24-18-13-7-4-8-14-18/h1-16H2,(H,21,25)(H,22,26) ☒NKey: RXSVYGIGWRDVQC-UHFFFAOYSA-N ☒N
SMILES C1CCC(=NOC(=O)NCCCCCCNC(=O)ON=C2CCCCC2)CC1
Properties
Chemical formula C20H34N4O4
Molar mass 394.26
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). ☒N verify (what is checkY☒N ?) Infobox references

Chemical compound

RHC80267 is an inhibitor of diacylglycerol lipase.[1] Diacylglycerol lipase generates the endocannabinoid 2-arachidonoylglycerol from diacylglycerol.

  1. ^ Sutherland CA, Amin D (1982). "Relative activities of rat and dog platelet phospholipase A2 and diglyceride lipase. Selective inhibition of diglyceride lipase by RHC 80267". J. Biol. Chem. 257 (23): 14006–10. PMID 7142192.