Ro05-4082 (original) (raw)
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Chemical compound
Pharmaceutical compound
Ro05-4082
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|---|---|
| Legal status | |
| Legal status | CA: Schedule IV DE: NpSG (Industrial and scientific use only) UK: Under Psychoactive Substances Act |
| Identifiers | |
| IUPAC name 5-(2-chlorophenyl)-1-methyl-7-nitro-3_H_-1,4-benzodiazepin-2-one | |
| CAS Number | 5527-71-9  Y |
| PubChem CID | 528222 |
| UNII | 89WG8CN9AJ |
| CompTox Dashboard (EPA) | DTXSID60203777  |
| Chemical and physical data | |
| Formula | C16H12ClN3O3 |
| Molar mass | 329.74 g·mol−1 |
| 3D model (JSmol) | Interactive image |
| SMILES CN1C(=O)CN=C(C2=C1C=CC(=C2)[N+](=O)[O-])C3=CC=CC=C3Cl | |
| InChI InChI=1S/C16H12ClN3O3/c1-19-14-7-6-10(20(22)23)8-12(14)16(18-9-15(19)21)11-4-2-3-5-13(11)17/h2-8H,9H2,1H3Key:AZVBJJDUDXZLTM-UHFFFAOYSA-N |
Ro05-4082 (N-methylclonazepam, ID-690) is a benzodiazepine derivative developed in the 1970s. It has sedative and hypnotic properties, and has around the same potency as clonazepam itself.[1] It was never introduced into clinical use. It is a structural isomer of meclonazepam (3-methylclonazepam), and similarly has been sold as a designer drug, first being identified in Sweden in 2017.[2]
- ^ Fukuda H, Kudo Y, Ono H, Togari A, Tanaka Y (January 1977). "[Pharmacological study on 5-(_o_-chlorophenyl)-1-methyl-7-nitro-1,3-dihydro-2_H_-1,4-benzodiazepin-2-one (ID-690), with special reference to the effects on motor systems]". Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica (in Japanese). 73 (1): 123–34. doi:10.1254/fpj.73.123. PMID 558942.
- ^ "Novel Benzodiazepines. A review of the evidence of use and harms of Novel Benzodiazepines" (PDF). Advisory Council on the Misuse of Drugs. April 2020.