SDF4 (original) (raw)

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Protein-coding gene in the species Homo sapiens

SDF4
Identifiers
Aliases	SDF4, Cab45, SDF-4, stromal cell derived factor 4
External IDs	OMIM: 614282; MGI: 108079; HomoloGene: 32121; GeneCards: SDF4; OMA:SDF4 - orthologs
Gene location (Human)Chr.Chromosome 1 (human)[1]Band1p36.33Start1,216,909 bp[1]End1,232,067 bp[1]
Gene location (Mouse)Chr.Chromosome 4 (mouse)[2]Band4|4 E2Start156,077,329 bp[2]End156,098,067 bp[2]
RNA expression patternBgeeHuman Mouse (ortholog)Top expressed instromal cell of endometriumright hemisphere of cerebellumcartilage tissuemucosa of transverse colonthoracic aortaascending aortaDescending thoracic aortaright auriclecardiaright coronary arteryTop expressed instroma of bone marrowmolarsupraoptic nucleusdentate gyrus of hippocampal formation granule cellspermatocytemesenteric lymph nodescalvariaright lung lobeduodenumsuperior frontal gyrusMore reference expression dataBioGPSMore reference expression data
Gene ontologyMolecular function protein binding metal ion binding identical protein binding calcium ion binding Cellular component cell projection extracellular exosome bleb late endosome Golgi lumen cytoplasm membrane plasma membrane Golgi apparatus endoplasmic reticulum Biological process UV protection zymogen granule exocytosis response to ethanol cerebellum development calcium-ion regulated exocytosis exocytosis fat cell differentiation Sources:Amigo / QuickGO
OrthologsSpeciesHuman MouseEntrez5115020318EnsemblENSG00000078808ENSMUSG00000029076UniProtQ9BRK5Q61112RefSeq (mRNA)NM_016176NM_016547NM_011341NM_001302467NM_001302468NM_001302469RefSeq (protein)NP_057260NP_057631NP_001289396NP_001289397NP_001289398NP_035471Location (UCSC)Chr 1: 1.22 – 1.23 MbChr 4: 156.08 – 156.1 MbPubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

45 kDa calcium-binding protein is a protein that in humans is encoded by the SDF4 gene.[5][6][7]

1. ^ a b c GRCh38: Ensembl release 89: ENSG00000078808 – Ensembl, May 2017
2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000029076 – Ensembl, May 2017
3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. ^ Koivu T, Laitinen S, Riento K, Olkkonen VM (Sep 1997). "Sequence of a human cDNA encoding Cab45, a Ca2+-binding protein with six EF-hand motifs". DNA Seq. 7 (3–4): 217–20. doi:10.3109/10425179709034038. PMID 9254016.
6. ^ Scherer PE, Lederkremer GZ, Williams S, Fogliano M, Baldini G, Lodish HF (May 1996). "Cab45, a novel (Ca2+)-binding protein localized to the Golgi lumen". J Cell Biol. 133 (2): 257–68. doi:10.1083/jcb.133.2.257. PMC 2120788. PMID 8609160.
7. ^ "Entrez Gene: SDF4 stromal cell derived factor 4".

• Honoré B, Vorum H (2000). "The CREC family, a novel family of multiple EF-hand, low-affinity Ca(2+)-binding proteins localised to the secretory pathway of mammalian cells". FEBS Lett. 466 (1): 11–8. doi:10.1016/S0014-5793(99)01780-9. PMID 10648803.
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.
• Lam PP, Hyvärinen K, Kauppi M, et al. (2007). "A cytosolic splice variant of Cab45 interacts with Munc18b and impacts on amylase secretion by pancreatic acini". Mol. Biol. Cell. 18 (7): 2473–80. doi:10.1091/mbc.E06-10-0950. PMC 1924827. PMID 17442889.