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Research Areas

Isn’t Science Beautiful?

The Institute for Systems Biology, where science solves problems, saves lives, and benefits human life on a global scale. If that’s not beautiful, we don’t know what is.

ISB Today

Our science is transforming health.

ISB is uncovering new solutions to the world’s most pressing health problems.

Career Opportunities

Great minds don’t think alike.

ISB employs over 170 staff from 25 countries. We are committed to fostering gender equity and increasing the representation of individuals from communities historically underrepresented in STEM.

man working in a lab

Cancer is complex and requires a sophisticated systems approach to understand and treat it. ISB researchers are pursuing several complex and cross-disciplinary means to better create more personalized therapeutics and simulate which treatments will be most effective.

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gibbons in the lab

Each of us has a microbiome — trillions of microorganisms that reside in and on our bodies. ISB researchers study the microbiome’s role in human health and translate this knowledge into approaches designed to promote better health for every individual.

View Microbiome Research

Members of the Kuchina Lab working at ISB in Seattle. (Photography by Scott Eklund/Red Box Pictures)

Our infectious disease research addresses a wide range of global health initiatives. We are exploring new approaches that focus on cutting-edge treatments and preventive measures to fight infectious diseases.

View Infectious Disease Research

2024 Year in Review

Reflecting on the past year, ISB has a lot to celebrate: groundbreaking research published in leading scientific journals, well-earned promotions, widespread media coverage, and more. Enjoy our year-in-review roundup highlighting some of the important, interesting, and impactful highlights of 2024.

2024 Year in Review

2024 Year in Review

mr. heath

Who We Are

President and Professor Jim Heath is dedicated to advancing precision medicine from benchtop to bedside, particularly in oncology. His research addresses fundamental scientific bottlenecks that can unlock solutions to broader challenges.

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Wei ISB

Who We Are

Professor Wei Wei’s research focuses on molecular and cellular analysis within systems biomedicine. The Wei Lab aims to tackle critical questions and foster new insights in fundamental and translational cancer research.

View Wei Lab Research

anna from isb

Who We Are

Assistant Professor Anna Kuchina studies bacteria at the single-cell level, using advanced technologies to understand how bacteria behave in complex settings such as biofilms living in the human body.

View Kuchina Lab Research