A RhoG-mediated signaling pathway that modulates invadopodia dynamics in breast cancer cells (original) (raw)
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Movie 6
Invadopodia formation in RhoG KD/rescue cells. RhoG KD SUM159 cells were co-infected with adenoviruses encoding mCherry-cortactin and shRNA resistant mycRhoG. At indicated times cells were stimulated to form invadopodia with PDBu. Images were captured at 15 sec intervals for the duration of the movie.
Silvia M. Goicoechea, Ashtyn Zinn, Sahezeel S. Awadia, Kyle Snyder, and Rafael Garcia-Mata
J Cell Sci 2017. 130:1064-1077; doi: 10.1242/jcs.195552