Topical Products for Healthy Aging | OneSkin (original) (raw)

A complete UV defense system backed by longevity science.

This summer, don’t stop at SPF. Reverse the visible effects of UV aging with the OS-01 Peptide TM.

OUR APPROACH

Led by science, not hype

Rigorous R&D platform

End-to-end product development run by our in-house team of scientists.

Scientifically validated claims

Quantified by our proprietary MolClock and Skin Age Modeling methods.

Ongoing clinical studies

Conducted by independent, third-party research organizations.

Peer-reviewed publications

The gold standard for scientific research and in skin care.

OUR APPROACH

The real proof? It’s in the numbers.

9

years of research

900

peptides screened

22

patents & publications

12000

5-Star Reviews

OUR BREAKTHROUGH PEPTIDE

OS-01: the new standard in peptide technology

Think of OS-01 as a reset button for your skin, helping clear away the senescent cells that cause wrinkles, hyperpigmentation, and crepiness. As the first peptide scientifically proven to reduce cellular senescence in the skin, OS-01 does what other peptides can’t. 01

6 visible signs of senescence

Lines and wrinkles

Caused by a decline in collagen and elastin production.

Loss of elasticity

Decreased elastin also contributes to lack of firmness.

Uneven skin tone

Irregular melanin production leads to hyperpigmentation.

Rough texture

Compromised skin cell renewal leaves a dry, uneven surface.

Loss of volume

Linked to a decrease in hyaluronic acid, collagen, and elastin.

Thinning skin

Slower cell turnover contributes to a weakened skin barrier.

DAILY ESSENTIALS

The 5-minute skin health routine

PREP Cleanser

OS-01 EYE

OS-01 FACE

OS-01 FACE SPF

Gently cleanse and exfoliate without irritation

Support delicate skin with the highest concentration of OS-01

A daily longevity serum and lightweight moisturizer in one

Repair UV aging while protecting against new UV-damage01

The Reference Lab

01 Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1
02 Zonari A., et al. Double-blind, vehicle-controlled clinical investigation of peptide OS-01 for skin rejuvenation. J Cosmet Dermatol. 2024; 23: 2135-2144. doi:10.1111/jocd.16242

03 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims 04 Zonari, A., et al. Clinical efficacy of OS-01 peptide formulation in reducing the signs of periorbital skin aging. Int J Cosmet Sci. 2025; 00: 1–11. doi:10.1111/ics.13042