Posttraumatic Stress Disorder, Obesity, and Accelerated Epigenetic Aging Among US Military Veterans (original) (raw)
Titles
Professor of Psychiatry and of Public Health (Social and Behavioral Sciences)
Director, Translational Psychiatric Epidemiology Laboratory, Clinical Neurosciences Division, U.S. Department of Veterans Affairs National Center for PTSD
Biography
Robert H. Pietrzak completed a B.A. in Psychology at Clark University, and M.P.H. in Epidemiology and Ph.D. in Clinical Psychology with specialization in Clinical Neuropsychology at the University of Connecticut. Dr. Pietrzak is Director of the Translational Psychiatric Epidemiology Laboratory in the Clinical Neurosciences Division of the U.S. Department of Veterans Affairs National Center for PTSD and Professor of Psychiatry at Yale University School of Medicine and Professor of Public Health (Social and Behavioral Sciences) at Yale School of Public Health. His primary research interests include the psychosocial and genetic epidemiology of traumatic stress and resilience across the lifespan; dimensional models of stress-related psychopathology; and the effect of stress on cognition.
Appointments
Education & Training
Fellowship in Clinical Neuropsychology
Gaylord Specialty Healthcare (2010)
PhD
University of Connecticut (2008)
Internship in Clinical Psychology
VA Connecticut Healthcare System-West Haven (2008)
MPH
University of Connecticut, Epidemiology (2003)
BA
Clark University, Psychology and Neuroscience (2001)
Overview
"Risk and Resilience Factors in Iraq Combat Veterans" - This study aims to improve understanding of the needs, symptoms, and strengths of Connecticut OIF/OEF Veterans.
"Mental Health, Resilience, and Soldier's Perceptions about Psychotherapy, Medication, and Barriers to Care in the U.S. Military" - This study aims to determine characteristics that differentiate symptomatic soldiers who seek mental health treatment and symptomatic soldiers who do not seek professional mental health treatment.
"National Health and Resilience in Veterans Study" - The purpose of this NCPTSD-funded study is to characterize genetic, environmental, and gene x environmental determinants of longitudinal trajectories of posttraumatic stress disorder and related mental health outcomes in a nationally representative sample of U.S. veterans.
"Trajectories of Psychological Risk and Resilience in World Trade Center Responders" - This CDC/NIOSH-funded study aims to characterize the nature and correlates of trajectories of posttraumatic stress symptoms of a large cohort of World Trade Center responders.
"Biomarkers of Psychological Risk and Resilience in World Trade Center Responders" - This CDC/NIOSH-funded study aims to examine genetic, epigenetic, and neuroendocrine factors associated with posttraumatic stress disorder in World Trade Center responders.
Medical Subject Headings (MeSH)
Anxiety Disorders; Resilience, Psychological; Stress Disorders, Post-Traumatic; Stress Disorders, Traumatic
Research at a Glance
Yale Co-Authors
Frequent collaborators of Robert Pietrzak's published research.
Jack Tsai
Ilan Harpaz-Rotem, PhD, ABPP
John Krystal, MD
Irina Esterlis, PhD
Joel Gelernter, MD
Publications
2024
Fischer I, Na P, Nagamatsu S, Jeste D, Cabrera-Mendoza B, Montalvo-Ortiz J, Krystal J, Polimanti R, Gelernter J, Pietrzak R. Posttraumatic Stress Disorder, Obesity, and Accelerated Epigenetic Aging Among US Military Veterans. JAMA Psychiatry 2024, 81 PMID: 39476130, DOI: 10.1001/jamapsychiatry.2024.3403.
Peer-Reviewed Original Research
Fischer I, Na P, Harpaz-Rotem I, Marx B, Pietrzak R. Prevalence, Correlates, and Burden of Subthreshold PTSD in US Veterans. The Journal Of Clinical Psychiatry 2024, 85 PMID: 39480145, DOI: 10.4088/jcp.24m15465.
Peer-Reviewed Original Research
MeSH Keywords and Concepts
Kang H, Fischer I, Vus V, Kolyshkina A, Ponomarenko L, Chobanian A, Esterlis I, Pietrzak R. Psychological Resilience of Mental Health Workers During the Russia-Ukraine War: Implications for Clinical Interventions. The Primary Care Companion For CNS Disorders 2024, 26 PMID: 39441963, DOI: 10.4088/pcc.24m03761.
Peer-Reviewed Original Research
MeSH Keywords and Concepts
Na P, Pietrzak R, Gelernter J. Genes in context: path to more precise risk prediction in psychiatry? The British Journal Of Psychiatry 2024, 1-2. PMID: 39422146, DOI: 10.1192/bjp.2024.151.
Peer-Reviewed Original Research
Ong A, Cintron D, Rottenberg J, Panaite V, Fischer I, Na P, Jeste D, Pietrzak R. Loneliness Trajectories in U.S. Military Veterans: A 3-Year Longitudinal Study of Risk and Protective Factors. The Journals Of Gerontology Series B 2024, gbae171. PMID: 39390809, DOI: 10.1093/geronb/gbae171.
Peer-Reviewed Original Research
Hyatt C, Reddi P, Sharpe B, Michopoulos V, van Rooij S, House S, Beaudoin F, An X, Stevens J, Zeng D, Neylan T, Clifford G, Linnstaedt S, Germine L, Bollen K, Rauch S, Haran J, Lewandowski C, Musey P, Hendry P, Sheikh S, Jones C, Punches B, Kurz M, Swor R, Hudak L, Pascual J, Seamon M, Harris E, Pearson C, Peak D, Merchant R, Domeier R, Rathlev N, Sergot P, Sanchez L, Bruce S, Miller M, Pietrzak R, Joormann J, Pizzagalli D, Sheridan J, Smoller J, Harte S, Elliott J, McLean S, Kessler R, Ressler K, Koenen K, Maples-Keller J. Longitudinal associations between five factor model and impulsive personality traits and PTSD symptoms: Findings from the AURORA study. Journal Of Research In Personality 2024, 112: 104524. DOI: 10.1016/j.jrp.2024.104524.
Peer-Reviewed Original Research
de Guillebon E, He C, Akhtar S, Pietrzak R, Ripp J, Peccoralo L. Association of Psychological Safety with Burnout and Intent to Leave Among Physician Faculty in New York City. Journal Of General Internal Medicine 2024, 1-7. PMID: 39354250, DOI: 10.1007/s11606-024-09034-9.
Peer-Reviewed Original Research
Chang C, Fischer I, Harper K, Livingston N, Depp C, Norman S, Pietrzak R. Sexual Orientation Moderates the Association Between Health Care Utilization-Related Factors and Mental Health Service Nonutilization Among United States Military Veterans. Psychological Services 2024 PMID: 39347751, DOI: 10.1037/ser0000907.
Peer-Reviewed Original Research
Stefanovics E, Potenza M, Tsai J, Pietrzak R. Gambling and Substance Use Disorders in U.S. Military Veterans: Prevalence, Clinical Characteristics, and Suicide Risk. Journal Of Gambling Studies 2024, 1-21. PMID: 39342537, DOI: 10.1007/s10899-024-10359-7.
Peer-Reviewed Original Research
Goldstein K, Pietrzak R, Challman K, Chu K, Beck K, Brenner L, Interian A, Myers C, Shafritz K, Szeszko P, Goodman M, Haznedar M, Hazlett E. Multi-modal risk factors differentiate suicide attempters from ideators in military veterans with major depressive disorder. Journal Of Affective Disorders 2024, 369: 588-598. PMID: 39341292, DOI: 10.1016/j.jad.2024.09.149.
Peer-Reviewed Original Research
Clinical Trials
Current Trials
HIC ID2000033404RoleSub InvestigatorPrimary Completion Date08/31/2025
Recruiting Participants
HIC ID2000025671RoleSub InvestigatorPrimary Completion Date07/31/2025
Recruiting Participants
HIC ID1511016789RoleSub InvestigatorPrimary Completion Date03/15/2022
Recruiting ParticipantsGenderBothAge18 years - 70 years
- activity
Psychological Injury and Law
Professional OrganizationsMember
- activity
Journal of Anxiety Disorders
Professional OrganizationsMember
- activity
PLoS One
Professional OrganizationsBoard Member
- honor
Outstanding Contributions to the Science of Trauma Psychology
National AwardAmerican Psychological Association
- honor
2022 Paul Wender Best Paper Award
National AwardAmerican Society of Clinical Psychopharmacology