amlodipine (CHEBI:2668) (original) (raw)

Monoisotopic Mass 408.14520
InChIKey HTIQEAQVCYTUBX-UHFFFAOYSA-N
SMILES CCOC(=O)C1=C(COCCN)NC(C)=C(C1c1ccccc1Cl)C(=O)OC
Roles Classification
Chemical Role(s): Bronsted base A molecular entity capable of accepting a hydron from a donor (Bronsted acid). (via organic amino compound )
Biological Role(s): calcium channel blocker One of a class of drugs that acts by selective inhibition of calcium influx through cell membranes or on the release and binding of calcium in intracellular pools.
Application(s): antihypertensive agent Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism. vasodilator agent A drug used to cause dilation of the blood vessels.

View more via ChEBI Ontology

Manual Xrefs Databases
183 DrugCentral
2963 VSDB
Amlodipine Wikipedia
C06825 KEGG COMPOUND
D07450 KEGG DRUG
DB00381 DrugBank
EP89167 Patent
LSM-1388 LINCS
US4572909 Patent
View more database links
Registry Numbers Types Sources
3570229 Reaxys Registry Number Reaxys
88150-42-9 CAS Registry Number DrugBank
88150-42-9 CAS Registry Number KEGG DRUG
88150-42-9 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
1532771 PubMed citation Europe PMC
16422032 PubMed citation Europe PMC
1834846 PubMed citation Europe PMC
19450066 PubMed citation Europe PMC
21591999 PubMed citation Europe PMC
7522286 PubMed citation Europe PMC
8310972 PubMed citation Europe PMC
8310973 PubMed citation Europe PMC
9156957 PubMed citation Europe PMC
Last Modified
22 February 2017