amlodipine (CHEBI:2668) (original) (raw)
Monoisotopic Mass | 408.14520 |
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InChIKey | HTIQEAQVCYTUBX-UHFFFAOYSA-N |
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SMILES | CCOC(=O)C1=C(COCCN)NC(C)=C(C1c1ccccc1Cl)C(=O)OC |
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Roles Classification | |
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Chemical Role(s): | Bronsted base A molecular entity capable of accepting a hydron from a donor (Bronsted acid). (via organic amino compound ) |
Biological Role(s): | calcium channel blocker One of a class of drugs that acts by selective inhibition of calcium influx through cell membranes or on the release and binding of calcium in intracellular pools. |
Application(s): | antihypertensive agent Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism. vasodilator agent A drug used to cause dilation of the blood vessels. |
Manual Xrefs | Databases |
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183 | DrugCentral |
2963 | VSDB |
Amlodipine | Wikipedia |
C06825 | KEGG COMPOUND |
D07450 | KEGG DRUG |
DB00381 | DrugBank |
EP89167 | Patent |
LSM-1388 | LINCS |
US4572909 | Patent |
View more database links |
Registry Numbers | Types | Sources |
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3570229 | Reaxys Registry Number | Reaxys |
88150-42-9 | CAS Registry Number | DrugBank |
88150-42-9 | CAS Registry Number | KEGG DRUG |
88150-42-9 | CAS Registry Number | ChemIDplus |
Citations | Types | Sources |
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1532771 | PubMed citation | Europe PMC |
16422032 | PubMed citation | Europe PMC |
1834846 | PubMed citation | Europe PMC |
19450066 | PubMed citation | Europe PMC |
21591999 | PubMed citation | Europe PMC |
7522286 | PubMed citation | Europe PMC |
8310972 | PubMed citation | Europe PMC |
8310973 | PubMed citation | Europe PMC |
9156957 | PubMed citation | Europe PMC |
Last Modified |
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22 February 2017 |