(E)-chlorprothixene (CHEBI:50932) (original) (raw)

CHEBI:50932 - (E)-chlorprothixene

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
Monoisotopic Mass 315.08485
InChIKey WSPOMRSOLSGNFJ-VGOFMYFVSA-N
SMILES CN(C)CC\C=C1/c2ccccc2Sc2ccc(Cl)cc12
Roles Classification
Chemical Role(s): Bronsted base A molecular entity capable of accepting a hydron from a donor (Bronsted acid). (via organic amino compound )
Biological Role(s): non-narcotic analgesic A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors. (via chlorprothixene ) cholinergic antagonist Any drug that binds to but does not activate cholinergic receptors, thereby blocking the actions of acetylcholine or cholinergic agonists. (via chlorprothixene ) dopaminergic antagonist A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists. (via chlorprothixene )
Application(s): non-narcotic analgesic A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors. (via chlorprothixene ) antiemetic A drug used to prevent nausea or vomiting. An antiemetic may act by a wide range of mechanisms: it might affect the medullary control centres (the vomiting centre and the chemoreceptive trigger zone) or affect the peripheral receptors. (via chlorprothixene ) sedative A central nervous system depressant used to induce drowsiness or sleep or to reduce psychological excitement or anxiety. (via chlorprothixene ) cholinergic antagonist Any drug that binds to but does not activate cholinergic receptors, thereby blocking the actions of acetylcholine or cholinergic agonists. (via chlorprothixene ) dopaminergic antagonist A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists. (via chlorprothixene ) first generation antipsychotic Antipsychotic drugs which can have different modes of action but which tend to be more likely than second generation antipsychotics to cause extrapyramidal motor control disabilities such as body rigidity or Parkinson's disease-type movements; such body movements can become permanent even after treatment has ceased. (via chlorprothixene )

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IUPAC Name
(3_E_)-3-(2-chloro-9_H_-thioxanthen-9-ylidene)-N,_N_-dimethylpropan-1-amine
Synonym Source
_trans_-chlorprothixene ChEBI
Manual Xref Database
DB01239 DrugBank
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Registry Number Type Source
265722 Beilstein Registry Number Beilstein
Citations Waiting for Citations Types Sources
1208553 PubMed citation Europe PMC
1682908 PubMed citation Europe PMC
1791531 PubMed citation Europe PMC
20952744 PubMed citation Europe PMC
2444901 PubMed citation Europe PMC
2865748 PubMed citation Europe PMC
8101879 PubMed citation Europe PMC
954816 PubMed citation Europe PMC
Last Modified
23 September 2021