Faculty | Koch Institute (original) (raw)

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Intramural faculty

Intramural faculty members have laboratories in the Koch Institute building.

Daniel Anderson

Professor Anderson develops devices, materials, and vaccines to create customizable living and gene therapies for cancer, diabetes, and other applications.

Angela Belcher

Professor Belcher seeks to understand and harness processes of nature to design materials and devices for cancer, energy, and the environment.

Michael Birnbaum

Professor Birnbaum focuses on understanding and manipulating adaptive immune responses in cancer and infection.

Jianzhu Chen

Professor Chen seeks fundamental understandings of the immune system and their translation into immunotherapies for cancer and other diseases.

Michael Cima

Professor Cima develops materials, diagnostics, and treatments to improve human health, focusing on cancer, metabolic diseases, trauma, and urological disorders.

Paula Hammond

Vice Provost for the Faculty

Professor Hammond designs polymers, including controlled-release films and nanoparticles for drug and nucleic acid delivery in cancer and other diseases.

Michael Hemann

Professor Hemann uses high throughput genetics and tractable pre-clinical models to investigate basic mechanisms of cancer drug resistance.

Whitney Henry

Professor Henry studies how ferroptosis, an iron-dependent form of cell death, can be leveraged to target highly metastatic and therapy-resistant cancer cells.

Susan Hockfield

A neuroscientist by training, Professor Hockfield is MIT President Emerita, and a longtime advocate for interdisciplinary research and convergence.

David Housman

Professor Housman studies the biological underpinnings of Huntington’s disease, cancer, and cardiovascular disease, to develop effective strategies for intervention.

Richard O. Hynes

Professor Hynes studies metastasis, the spread of tumor cells throughout the body, particularly the role of extracellular matrix, an important component of tumor microenvironment.

Tyler Jacks

Co-Director, Ludwig Center at MIT

Professor Jacks investigates the events contributing to cancer evolution, and has engineered widely-used mouse models of human cancers.

Kristin Knouse

Professor Knouse studies the differential regenerative ability of mammalian organs, seeking new treatments for conditions ranging from organ injury to cancer.

Angela Koehler

Associate Director
Faculty Director, MIT Deshpande Center

Professor Koehler’s lab applies chemical biology approaches to expand the ‘druggable’ proteome, emphasizing proteins that are dysregulated in cancer.

Robert Langer

Professor Langer develops drug delivery systems and tissue engineering systems for numerous applications, including cancer therapy, diabetes, and vaccines.

Jacqueline Lees

Associate Dean, MIT School of Science

Professor Lees investigates genes that influence cancer development and progression, with particular focus on regulators that control stem cell function.

J. Christopher Love

Professor Love develops single-cell analysis and biomanufacturing technologies to accelerate the discovery and production of vaccines, cancer therapeutics, and biomedicines.

Scott Manalis

Professor Manalis develops novel instrumentation for cancer research.

Francisco J. Sánchez-Rivera

Professor Sánchez-Rivera aims to understand how genes and disease-predisposing mutations interact with and within an individual’s genome to influence disease.

Ram Sasisekharan

Professor Sasisekharan studies how cell function is regulated by the extracellular environment, and develops antibody engineering tools for infectious disease and cancer.

Phillip Sharp

The Sharp Laboratory investigates transcription and RNA splicing to identify signatures for early cancer detection and novel therapeutic targets.

Professor Soto-Feliciano studies how chromatin regulates gene expression and how these molecular mechanisms are altered in cancer, with the goal of uncovering targets for the next generation of cancer treatments.

Stefani Spranger

Professor Spranger studies the mechanisms underlying interactions between cancer and the immune system.

Jessica Stark

Professor Stark seeks to understand and engineer the roles of cell-surface sugars in the immune system.

Matthew Vander Heiden

Director, Koch Institute

Professor Vander Heiden studies how metabolism is altered in cancer and seeks to understand and identify metabolic targets for cancer therapy.

Forest White

Professor White uses systems biology and computational modeling to characterize signaling networks and the tumor-immune interface to identify therapeutic targets.

Dane Wittrup

Professor Wittrup develops protein engineering technologies for the discovery and improvement of cancer biopharmaceuticals and immunotherapies.

Michael Yaffe

Director, MIT Center for Precision Cancer Medicine

Professor Yaffe studies signaling networks that control cellular stress responses, including DNA damage responses, inflammation, and cell cycle progression in cancer development and treatment.

Ömer Yilmaz

Professor Yilmaz studies and models the effects of various diets in tissue regeneration, aging, and cancer initiation.

Extramural faculty

Extramural faculty members come from departments and centers across the MIT campus to share in the vision of the Koch Institute.

Emeritus and former faculty

Recognizing tenured, intramural Koch Institute faculty members who have passed away or no longer have active laboratories.