Bioinformatics Institute - Featured On Influenza Initiative (original) (raw)

The Bioinformatics Institute (BII) was set up by the Agency for Science, Technology and Research (A*STAR) in July 2001; it was re-launched with a strong scientific program in 2007. Located in the Biopolis in Singapore, BII is conceived as the computational biology research and postgraduate training institute as well as a national resource centre in bioinformatics within the Biomedical Research Council (BMRC) of A*STAR.

The Bioinformatics Institute (BII) aims to understand the biomolecular mechanisms that underlie biomedical phenomena by developing sophisticated computational methods to support this discovery process from a secure and sustainable data hub to cross-disciplinary AI/ML analysis and data integration. We analyse a wide spectrum of biological and clinical data, including omics data (biomolecular sequences, expression profiles, epigenetics data), 3D structures of macromolecules, and biological tissue and macroscopic images from local and international academic, hospital and industry collaborators, public resources and from our own experiments. Our applied research diversifies into infectious diseases, computational toxicology, natural product research, precision medicine, cancer research, and drug discovery.


Research Divisions

Biomolecular Sequence to Functions
Biomolecular Structure to Mechanism
Cellular Image Informatics
Biomedical Data Hub

Events

Wednesday, 23 October 2024

BII Seminar: Making BioImage Data FAIR on a Global Scale: OME’s Bio-Formats, OMERO, & IDR

2024-10-23 3:00 PM SGT to 2024-10-23 4:00 PM SGT

Speaker : Prof Jason Swedlow, Molecular Cell and Developmental Biology, School of Life Sciences, University of Dundee

Tuesday, 15 October 2024

BII Seminar: Quantum computing for data analysis

2024-10-15 3:00 PM SGT to 2024-10-15 4:00 PM SGT

Alanine Meeting Room, Matrix Level 7

Speaker: Dr. Jayne Elizabeth Donovan Thompson, Senior Principal Scientist, IHPC & QInC (A*STAR)

Meeting ID : 922 5373 1819

Passcode : 553614

Wednesday, 30 October 2024

BII Seminar: Conformational Sampling, Thermodynamic Landscapes and Chemical Intuitions: Computational Routes to the Molecular Mechanisms of Biomolecules

2024-10-30 10:00 AM SGT to 2024-10-30 11:00 AM SGT

Cysteine Meeting Room, Matrix Level 7

Speaker: Prof Shubhra Ghosh Dastidar, Dept of Biological Sciences, Bose Institute, India

Meeting ID : 953 5107 3775

Passcode : 762800

Thursday, 07 November 2024

BII Seminar: High-Resolution Molecular Dynamics Simulations for Biophysics

2024-11-07 4:00 PM SGT to 2024-11-07 5:00 PM SGT

Cysteine Meeting Room, Matrix Level 7

Speaker: Prof. Jean Philip Piquemal, CSO & co-founder Qubit Pharmaceuticals

Meeting ID : 912 7570 8392

Passcode : 388945

Wednesday, 16 October 2024

BII Seminar: Beyond transcriptomics, mass spectrometry based proteomics, from bulk to single cell analysis

2024-10-16 3:00 PM SGT to 2024-10-16 4:00 PM SGT

Cysteine Meeting Room, Matrix Level 7

Speaker : Dr Radoslaw Sobota, Principal Scientist, Institute of Molecular and Cell Biology

Thursday, 24 October 2024

BII Seminar: The Search for a Novel Pyruvate Kinase Activator - From a HTS Hit via an Impurity to the Discovery of a Lead Series

2024-10-24 10:00 AM SGT to 2024-10-24 11:00 AM SGT

Cysteine Meeting Room, Matrix Level 7

Speaker: Dr. Shahul Nilar

Thursday, 03 October 2024

BII Seminar: Generative Design and Synthesis Prediction in Modern Drug Discovery

2024-10-03 1:30 PM SGT to 2024-10-03 2:30 PM SGT

Codon A & B, Matrix Level 5

Speaker : Dr. Kenneth Atz, AI Scientist, Roche

Host: Dr. Sebastian Maurer-Stroh, Executive Director, BII

Friday, 20 September 2024

BII Science Unplugged 1

2024-09-20 4:00 PM SGT to 2024-09-20 5:00 PM SGT

Cysteine-Glycine meeting rooms

Justice Undone: Misapplied Science in Crime Investigations, by Olga Sirbu.

Serendipity in Science, by Pietro Aronica.

Tuesday, 01 October 2024

BII IBIDA course: Theoretical Aspects of Generative Models

2024-10-01 6:30 PM SGT to 2024-10-01 8:30 PM SGT

Kindly reach out to the IBIDA course organizers via the following email, IBIDA@bii.a-star.edu.sg. Registration will close on 29th September 2024, 2359 SGT.

Thursday, 26 September 2024

BII Seminar: The Molecular Basis of RNA Virus Antigenic Shift

2024-09-26 3:00 PM SGT to 2024-09-26 4:00 PM SGT

Cysteine/Glycine Meeting Room, Matrix Level 7

Bioinformatics Institute (BII) would like to invite you to attend the following seminar:

Speaker : Dr. David LV Bauer, Virologist, The Francis Crick Institute, UK

Thursday, 12 September 2024

BII Seminar: A whole-slide foundation model for digital pathology from real-world data,

2024-09-12 4:00 PM SGT to 2024-09-12 5:00 PM SGT

Boardroom, Matrix Level 8

Bioinformatics Institute (BII) would like to invite you to attend the following seminar:

Speaker : Dr Poon Hoifung, General Manager, Microsoft Health Futures

Monday, 12 August 2024

BII Seminar: AI for Predictive Analytics in the Development of Novel Therapeutics

2024-08-12 11:00 AM SGT to 2024-08-12 12:00 PM SGT

Cysteine Meeting Room, Matrix Level 7

Speaker : Dr James Lu, Distinguished AI Scientist, Genentech

Wednesday, 21 August 2024

Joint Seminar: BII-AI3 Special Interest Group of Digital Health Seminar

2024-08-21 10:00 AM SGT to 2024-08-21 11:00 AM SGT

Cysteine Meeting Room, Matrix Level 7

Speaker : Dr Dianbo Lu, Department of Biomedical Informatics, National University of Singapore

Monday, 26 August 2024

BII Seminar: Robust Spatial Biomarker Development Through AI-enabled Virtual Staining

2024-08-26 1:00 PM SGT to 2024-08-26 2:00 PM SGT

Cysteine Meeting Room, Matrix Level 7

Speaker : Dr Mai Chan Lau, Assistant Principal Investigator, Bioinformatics Institute (BII)

Friday, 26 July 2024

BII Seminar: Using simulation to understand the mechanism of transport and drug uptake in Peptide Transporters

2024-07-26 10:30 AM SGT to 2024-07-26 11:30 AM SGT

Cysteine Meeting Room, Matrix Level 7

Speaker : Prof Philip Biggin, Professor of Computational Biochemistry, Dept of Biochemistry, University of Oxford

Tuesday, 23 July 2024

BII Seminar: In silico enzymology - modelling enzymes using computational tools

2024-07-23 2:00 PM SGT to 2024-07-23 3:00 PM SGT

Cysteine Meeting Room, Matrix Level 7

Speaker : Prof Sam Hay, Computational Theoretical Chemistry, University of Manchester

Wednesday, 26 June 2024

BII Seminar: Targeting an oncofetal protein SALL4 in cancer

2024-06-26 10:30 AM SGT to 2024-06-26 11:30 AM SGT

Cysteine Meeting Room, Matrix Level 7

Speaker : Dr Li Chai, Pathology/Transfusion Medicine, Brigham and Women’s Hospital/Harvard Medical School

Tuesday, 18 June 2024

BII Seminar: Targeting Energy of Life for Eradication of antibiotic-resistant bacterial pathogens

2024-06-18 10:30 AM SGT to 2024-06-18 11:30 AM SGT

Cysteine Meeting Room, Matrix Level 7

Speaker : Prof. Dr. Gerhard Grüber, School of Biological Sciences, Nanyang Technological University, Singapore

Tuesday, 25 June 2024

BII Seminar: Developing new CADD methods for Drug Discovery and Relocalization

2024-06-25 10:30 AM SGT to 2024-06-25 12:00 PM SGT

Cysteine Meeting Room, Matrix Level 7

Speaker : Prof Zhu Weiliang, Principal Investigator, Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CAS)

Friday, 07 June 2024

BII Event: BII Scientific Conference 2024

2024-06-07 9:00 AM SGT to 2024-06-07 5:30 PM SGT

Multi-Purpose Halls 1 & 2, Level 1, Innovis Building, 2 Fusionopolis Way, Singapore 138634

Please go to the page for the updated program.

BII Scientific Conference 2024

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