Table of Pharmacogenomic Biomarkers (original) (raw)

Abacavir

Infectious Diseases

HLA-B

Boxed Warning, Dosage and Administration, Contraindications, Warnings and Precautions

Abemaciclib (1)

Oncology

ESR
(Hormone Receptor)

Indications and Usage, Adverse Reactions, Clinical Studies

Abemaciclib (2)

Oncology

ERBB2
(HER2)

Indications and Usage, Adverse Reactions, Clinical Studies

Abemaciclib (3)

Oncology

MKI67

Clinical Studies

Abrocitinib

Dermatology

CYP2C19

Dosage and Administration, Use in Specific Populations, Clinical Pharmacology

Adagrasib

Oncology

KRAS

Indications and Usage, Dosage and Administration, Adverse Reactions, Clinical Pharmacology, Clinical Studies

Ado-Trastuzumab Emtansine

Oncology

ERBB2
(HER2)

Indications and Usage, Dosage and Administration, Adverse Reactions, Clinical Pharmacology, Clinical Studies

Aducanumab-avwa

Neurology

APOE

Boxed Warning, Warnings and Precautions, Clinical Studies, Patient Counseling Information

Afatinib

Oncology

EGFR

Indications and Usage, Dosage and Administration, Adverse Reactions, Clinical Studies

Alectinib

Oncology

ALK

Indications and Usage, Dosage and Administration, Adverse Reactions, Clinical Pharmacology, Clinical Studies

Alglucosidase Alfa

Inborn Errors of Metabolism

GAA

Warnings and Precautions

Allopurinol

Oncology

HLA-B

Warnings

Alpelisib (1)

Oncology

ERBB2
(HER2)

Indication and Usage, Dosage and Administration, Adverse Reactions, Clinical Studies

Alpelisib (2)

Oncology

ESR
(Hormone Receptor)

Indication and Usage, Dosage and Administration, Adverse Reactions, Clinical Studies

Alpelisib (3)

Oncology

PIK3CA

Indication and Usage, Dosage and Administration, Adverse Reactions, Clinical Studies

Amifampridine Phosphate

Neurology

NAT2

Dosage and Administration, Use in Specific Populations, Clinical Pharmacology

Amikacin

Infectious Diseases

MT-RNR1

Warnings and Precautions

Amitriptyline

Psychiatry

CYP2D6

Precautions

Amivantamab-vmjw

Oncology

EGFR

Indications and Usage, Dosage and Administration, Adverse Reactions, Clinical Studies

Amoxapine

Psychiatry

CYP2D6

Precautions

Amphetamine

Psychiatry

CYP2D6

Clinical Pharmacology

Anakinra

Rheumatology

NLRP3

Indications and Usage, Dosage and Administration, Warnings and Precautions, Adverse Reactions, Use in Specific Populations, Clinical Pharmacology, Clinical Studies

Anastrozole

Oncology

ESR, PGR
(Hormone Receptor)

Indications and Usage, Adverse Reactions, Drug Interactions, Clinical Studies

Anifrolumab-fnia

Rheumatology

Gene Signature
(IFN)

Clinical Pharmacology, Clinical Studies

Arformoterol (1)

Pulmonary

UGT1A1

Clinical Pharmacology

Arformoterol (2)

Pulmonary

CYP2D6

Clinical Pharmacology

Aripiprazole

Psychiatry

CYP2D6

Dosage and Administration, Use in Specific Populations, Clinical Pharmacology

Aripiprazole Lauroxil

Psychiatry

CYP2D6

Dosage and Administration, Use in Specific Populations, Clinical Pharmacology

Arsenic Trioxide

Oncology

PML-RARA

Indications and Usage, Clinical Studies

Articaine and Epinephrine (1)

Anesthesiology

G6PD

Warnings and Precautions

Articaine and Epinephrine (2)

Anesthesiology

Nonspecific
(Congenital Methemoglobinemia)

Warnings and Precautions

Asciminib

Oncology

BCR-ABL1
(Philadelphia chromosome)

Indications and Usage, Dosage and Administration, Adverse Reactions, Use in Specific Populations, Clinical Studies

Ascorbic Acid

Endocrinology

G6PD

Dosage and Administration, Warnings and Precautions, Adverse Reactions, Patient Counseling Information

Atezolizumab (1)

Oncology

CD274
(PD-L1)

Indications and Usage, Dosage and Administration, Adverse Reactions, Clinical Pharmacology, Clinical Studies

Atezolizumab (2)

Oncology

Gene Signature
(T-effector)

Clinical Studies

Atezolizumab (3)

Oncology

EGFR

Indications and Usage, Adverse Reactions, Clinical Studies

Atezolizumab (4)

Oncology

ALK

Indications and Usage, Adverse Reactions, Clinical Studies

Atezolizumab (5)

Oncology

BRAF

Indications and Usage, Dosage and Administration, Adverse Reactions, Clinical Studies

Atomoxetine

Psychiatry

CYP2D6

Dosage and Administration, Warnings and Precautions, Adverse Reactions, Drug Interactions, Use in Specific Populations, Clinical Pharmacology

Ascorbic Acid, PEG-3350, Potassium Chloride, Sodium Ascorbate, Sodium Chloride, and Sodium Sulfate

Gastroenterology

G6PD

Warnings and Precautions, Adverse Reactions

Avapritinib (1)

Oncology

PDGFRA

Indications and Usage, Dosage and Administration, Clinical Studies

Avapritinib (2)

Oncology

KIT

Clinical Studies

Avatrombopag (1)

Hematology

F2
(Prothrombin)

Warnings and Precautions

Avatrombopag (2)

Hematology

F5
(Factor V Leiden)

Warnings and Precautions

Avatrombopag (3)

Hematology

PROC

Warnings and Precautions

Avatrombopag (4)

Hematology

PROS1

Warnings and Precautions

Avatrombopag (5)

Hematology

SERPINC1
(Antithrombin III)

Warnings and Precautions

Avatrombopag (6)

Hematology

CYP2C9

Clinical Pharmacology

Avelumab

Oncology

CD274
(PD-L1)

Clinical Studies

Azacitidine (1)

Oncology

CBL

Clinical Studies

Azacitidine (2)

Oncology

PTPN11

Clinical Studies

Azacitidine (3)

Oncology

RAS

Clinical Studies

Azathioprine (1)

Rheumatology

TPMT

Dosage and Administration, Warnings, Precautions, Drug Interactions, Adverse Reactions, Clinical Pharmacology

Azathioprine (2)

Rheumatology

NUDT15

Dosage and Administration, Warnings, Precautions, Adverse Reactions, Clinical Pharmacology

Belinostat

Oncology

UGT1A1

Dosage and Administration, Clinical Pharmacology

Belzutifan (1)

Oncology

CYP2C19

Warnings and Precautions, Drug Interactions, Use in Specific Populations, Clinical Pharmacology

Belzutifan (2)

Oncology

UGT2B17

Warnings and Precautions, Drug Interactions, Use in Specific Populations, Clinical Pharmacology

Belzutifan (3)

Oncology

VHL

Clinical Studies

Bempedoic Acid and Ezetimibe

Endocrinology

Nonspecific
(Heterozygous Familial Hypercholesterolemia)

Indications and Usage, Adverse Reactions, Clinical Studies

Betaine

Inborn Errors of Metabolism

CBS, MMADHC, MTHFR (Homocystinuria Deficiency)

Indications and Usage, Warnings and Precautions, Clinical Pharmacology, Clinical Studies

Binimetinib (1)

Oncology

BRAF

Indications and Usage, Adverse Reactions, Use in Specific Populations, Clinical Pharmacology, Clinical Studies

Binimetinib (2)

Oncology

UGT1A1

Indications and Usage, Use in Specific Populations

Blinatumomab (1)

Oncology

BCR-ABL1
(Philadelphia chromosome)

Indications and Usage, Adverse Reactions, Use in Specific Populations, Clinical Pharmacology, Clinical Studies

Blinatumomab (2)

Oncology

CD19

Indications and Usage, Use in Specific Populations

Boceprevir

Infectious Diseases

IFNL3
(IL28B)

Clinical Pharmacology

Bosutinib

Oncology

BCR-ABL1
(Philadelphia chromosome)

Indications and Usage, Dosage and Administration, Warnings and Precautions, Adverse Reactions, Use in Specific Populations, Clinical Studies

Brentuximab Vedotin (1)

Oncology

ALK

Use in Specific Populations, Clinical Studies

Brentuximab Vedotin (2)

Oncology

TNFRSF8
(CD30)

Indications and Usage, Dosage and Administration, Adverse Reactions, Use in Specific Populations, Clinical Studies

Brexpiprazole

Psychiatry

CYP2D6

Dosage and Administration, Use in Specific Populations, Clinical Pharmacology

Brigatinib

Oncology

ALK

Indications and Usage, Dosage and Administration, Adverse Reactions, Clinical Studies

Brivaracetam

Neurology

CYP2C19

Clinical Pharmacology

Bupivacaine (1)

Anesthesiology

G6PD

Warnings

Bupivacaine (2)

Anesthesiology

Nonspecific
(Congenital Methemoglobinemia)

Warnings

Bupropion

Psychiatry

CYP2D6

Clinical Pharmacology

Bupropion and Dextromethorphan

Psychiatry

CYP2D6

Dosage and Administration, Use in Specific Populations, Clinical Pharmacology

Busulfan

Oncology

BCR-ABL1
(Philadelphia chromosome)

Clinical Studies

Cabotegravir and Rilpivirine (1)

Infectious Diseases

HLA-B

Clinical Studies

Cabotegravir and Rilpivirine (2)

Infectious Diseases

UGT1A1

Clinical Pharmacology

Cabozantinib

Oncology

RET

Clinical Studies

Capmatinib

Oncology

MET

Indications and Usage, Dosage and Administration, Clinical Studies

Capecitabine (1)

Oncology

DPYD

Warnings and Precautions, Clinical Pharmacology, Patient Counseling Information

Capecitabine (2)

Oncology

ERBB2
(HER2)

Indications and Usage, Dosage and Administration, Adverse Reactions, Clinical Studies

Capivasertib (1)

Oncology

AKT1

Indications and Usage, Dosage and Administration, Adverse Reactions, Clinical Studies

Capivasertib (2)

Oncology

ERBB2
(HER2)

Indications and Usage, Dosage and Administration, Clinical Studies

Capivasertib (3)

Oncology

ESR
(Hormone Receptor)

Indications and Usage, Dosage and Administration, Clinical Studies

Capivasertib (4)

Oncology

PIK3CA

Indications and Usage, Dosage and Administration, Adverse Reactions, Clinical Studies

Capivasertib (5)

Oncology

PTEN

Indications and Usage, Dosage and Administration, Adverse Reactions, Clinical Studies

Carbamazepine (1)

Neurology

HLA-B

Boxed Warning, Warnings, Precautions

Carbamazepine (2)

Neurology

HLA-A

Warnings

Carglumic Acid

Inborn Errors of Metabolism

NAGS

Indications and Usage, Dosage and Administration, Warnings and Precautions, Use in Specific Populations, Clinical Pharmacology, Clinical Studies

Cariprazine

Psychiatry

CYP2D6

Clinical Pharmacology

Carisoprodol

Rheumatology

CYP2C19

Use in Specific Populations, Clinical Pharmacology

Carvedilol

Cardiology

CYP2D6

Drug Interactions, Clinical Pharmacology

Casimersen

Neurology

DMD

Indications and Usage, Adverse Reactions, Use in Specific Populations, Clinical Pharmacology, Clinical Studies

Ceftriaxone (1)

Infectious Diseases

G6PD

Warnings

Ceftriaxone (2)

Infectious Diseases

Nonspecific
(Congenital Methemoglobinemia)

Warnings

Celecoxib

Rheumatology

CYP2C9

Dosage and Administration, Use in Specific Populations, Clinical Pharmacology

Cemiplimab-rwlc (1)

Oncology

ALK

Indications and Usage, Clinical Studies

Cemiplimab-rwlc (2)

Oncology

CD274
(PD-L1)

Indications and Usage, Dosage and Administration, Clinical Studies

Cemiplimab-rwlc (3)

Oncology

EGFR

Indications and Usage, Clinical Studies

Cemiplimab-rwlc (4)

Oncology

ROS1

Indications and Usage, Clinical Studies

Ceritinib

Oncology

ALK

Indications and Usage, Dosage and Administration, Warning and Precautions, Adverse Reactions, Clinical Studies

Cerliponase Alfa

Inborn Errors of Metabolism

TPP1

Indications and Usage, Use in Specific Populations, Clinical Studies

Cetuximab (1)

Oncology

EGFR

Indications and Usage, Dosage and Administration, Adverse Reactions, Clinical Studies

Cetuximab (2)

Oncology

RAS

Indications and Usage, Dosage and Administration, Warnings and Precautions, Adverse Reactions, Clinical Studies

Cetuximab (3)

Oncology

BRAF

Indications and Usage, Dosage and Administration, Adverse Reactions, Use in Specific Populations, Clinical Studies

Cevimeline

Dental

CYP2D6

Precautions

Chloroprocaine (1)

Anesthesiology

G6PD

Warnings

Chloroprocaine (2)

Anesthesiology

Nonspecific
(Congenital Methemoglobinemia)

Warnings

Chloroquine

Infectious Diseases

G6PD

Precautions, Adverse Reactions

Chlorpropamide

Endocrinology

G6PD

Precautions

Cholic Acid

Inborn Errors of Metabolism

AMACR, AKR1D1, CYP7A1, CYP27A1, DHCR7, HSD3B2
(Bile Acid Synthesis Disorders)

Indications and Usage, Dosage and Administration, Warnings and Precautions, Adverse Reactions, Use in Specific Populations, Clinical Studies

Cisplatin

Oncology

TPMT

Adverse Reactions

Citalopram (1)

Psychiatry

CYP2C19

Dosage and Administration, Warnings, Clinical Pharmacology

Citalopram (2)

Psychiatry

CYP2D6

Clinical Pharmacology

Clobazam

Neurology

CYP2C19

Dosage and Administration, Use in Specific Populations, Clinical Pharmacology

Clomipramine

Psychiatry

CYP2D6

Precautions

Clopidogrel

Cardiology

CYP2C19

Boxed Warning, Warnings and Precautions, Clinical Pharmacology

Clozapine

Psychiatry

CYP2D6

Dosage and Administration, Use in Specific Populations, Clinical Pharmacology

Cobimetinib

Oncology

BRAF

Indications and Usage, Dosage and Administration, Adverse Reactions, Clinical Studies

Codeine

Anesthesiology

CYP2D6

Boxed Warning, Warnings and Precautions, Use in Specific Populations, Patient Counseling Information

Crizanlizumab-tmca

Hematology

HBB

Adverse Reactions, Clinical Studies

Crizotinib (1)

Oncology

ALK

Indications and Usage, Dosage and Administration, Adverse Reactions, Use in Specific Populations, Clinical Pharmacology, Clinical Studies

Crizotinib (2)

Oncology

ROS1

Indications and Usage, Dosage and Administration, Adverse Reactions, Use in Specific Populations, Clinical Studies

Dabrafenib (1)

Oncology

BRAF

Indications and Usage, Dosage and Administration, Warnings and Precautions, Adverse Reactions, Use in Specific Populations, Clinical Pharmacology, Clinical Studies

Dabrafenib (2)

Oncology

G6PD

Warnings and Precautions, Adverse Reactions, Patient Counseling Information

Dabrafenib (3)

Oncology

RAS

Dosage and Administration, Warnings and Precautions

Daclatasvir

Infectious Diseases

IFNL3
(IL28B)

Clinical Studies

Dacomitinib

Oncology

EGFR

Indications and Usage, Dosage and Administration, Adverse Reactions, Use in Specific Populations, Clinical Studies

Dapsone (1)

Dermatology

G6PD

Warnings and Precautions, Use in Specific Populations, Patient Counseling Information

Dapsone (2)

Dermatology

Nonspecific
(Congenital Methemoglobinemia)

Warnings and Precautions, Adverse Reactions, Patient Counseling Information

Dapsone (3)

Infectious Diseases

G6PD

Precautions, Adverse Reactions, Overdosage

Darifenacin

Urology

CYP2D6

Clinical Pharmacology

Dasabuvir, Ombitasvir, Paritaprevir, and Ritonavir

Infectious Diseases

IFNL3
(IL28B)

Clinical Studies

Dasatinib

Oncology

BCR-ABL1
(Philadelphia chromosome)

Indications and Usage, Dosage and Administration, Warnings and Precautions, Adverse Reactions, Use in Specific Populations, Clinical Studies

Denileukin Diftitox

Oncology

IL2RA
(CD25 antigen)

Indications and Usage, Clinical Studies

Desipramine

Psychiatry

CYP2D6

Precautions

Desflurane

Anesthesiology

CACNA1S, RYR1
(Genetic Susceptibility to Malignant Hyperthermia)

Contraindications, Warnings and Precautions, Clinical Pharmacology

Desmopressin

Hematology

Indications and Usage, Dosage and Administration, Clinical Pharmacology

Desvenlafaxine

Psychiatry

CYP2D6

Clinical Pharmacology

Deutetrabenazine

Neurology

CYP2D6

Dosage and Administration, Use in Specific Populations, Clinical Pharmacology

Dexlansoprazole

Gastroenterology

CYP2C19

Drug Interactions, Clinical Pharmacology

Dextromethorphan and Quinidine

Neurology

CYP2D6

Warnings and Precautions, Clinical Pharmacology

Diazepam

Neurology

CYP2C19

Clinical Pharmacology

Dinutuximab

Oncology

MYCN

Clinical Studies

Docetaxel

Oncology

ESR, PGR
(Hormone Receptor)

Clinical Studies

Dolutegravir

Infectious Diseases

UGT1A1

Clinical Pharmacology

Donepezil

Neurology

CYP2D6

Clinical Pharmacology

Dostarlimab-gxly

Oncology

Microsatellite Instability, Mismatch Repair

Indications and Usage, Dosage and Administration, Adverse Reactions, Clinical Studies

Doxepin (1)

Psychiatry

CYP2D6

Clinical Pharmacology

Doxepin (2)

Psychiatry

CYP2C19

Clinical Pharmacology

Dronabinol

Gastroenterology

CYP2C9

Use in Specific Populations, Clinical Pharmacology

Drospirenone and Ethinyl Estradiol

Gynecology

CYP2C19

Clinical Pharmacology

Duloxetine

Psychiatry

CYP2D6

Drug Interactions

Durvalumab (1)

Oncology

ALK

Indications and Usage, Clinical Studies

Durvalumab (2)

Oncology

EGFR

Indications and Usage, Clinical Studies

Durvalumab (3)

Oncology

CD274
(PD-L1)

Clinical Pharmacology, Clinical Studies

Durvalumab (4)

Oncology

Mismatch Repair

Indications and Usage, Dosage and Administration, Adverse Reactions, Clinical Studies

Duvelisib

Oncology

Chromosome 17p

Clinical Studies

Eculizumab (1)

Neurology

ACHR

Indications and Usage, Clinical Studies

Eculizumab (2)

Neurology

AQP4

Indications and Usage, Clinical Studies

Efavirenz

Infectious Diseases

CYP2B6

Clinical Pharmacology

Efgartigimod Alfa-fcab

Neurology

ACHR

Indications and Usage, Clinical Pharmacology, Clinical Studies

Eflornithine

Oncology

MYCN

Adverse Reactions, Clinical Studies

Elacestrant (1)

Oncology

ESR
(Hormone Receptor)

Indications and Usage, Dosage and Administration, Adverse Reactions, Clinical Studies

Elacestrant (2)

Oncology

ERBB2
(HER2)

Indications and Usage, Dosage and Administration, Adverse Reactions, Clinical Studies

Elagolix

Gynecology

SLCO1B1

Clinical Pharmacology

Elbasvir and Grazoprevir

Infectious Diseases

IFNL3
(IL28B)

Clinical Studies

Elexacaftor, Ivacaftor, and Tezacaftor

Pulmonary

CFTR

Indications and Usage, Use in Specific Populations, Clinical Pharmacology, Clinical Studies

Eliglustat

Inborn Errors of Metabolism

CYP2D6

Indications and Usage, Dosage and Administration, Contraindications, Warnings and Precautions, Drug Interactions, Use in Specific Populations, Clinical Pharmacology, Clinical Studies

Elranatamab-bcmm (1)

Oncology

Chromosome 17p

Clinical Studies

Elranatamab-bcmm (2)

Oncology

Chromosome 4p;14q

Clinical Studies

Elranatamab-bcmm (3)

Oncology

Chromosome 14q;16q

Clinical Studies

Elosulfase

Inborn Errors of Metabolism

GALNS

Indications and Usage, Warnings and Precautions, Use in Specific Populations, Clinical Pharmacology, Clinical Studies

Eltrombopag (1)

Hematology

F5
(Factor V Leiden)

Warnings and Precautions

Eltrombopag (2)

Hematology

SERPINC1
(Antithrombin III)

Warnings and Precautions

Eltrombopag (3)

Hematology

Chromosome 7

Adverse Reactions

Eltrombopag (4)

Hematology

Chromosome 13

Adverse Reactions

Emapalumab-lzsg

Hematology

PRF1, RAB27A, SH2D1A, STXBP2, STX11, UNC13D, XIAP (Hemophagocytic Lymphohistiocytosis)

Clinical Studies

Enasidenib

Oncology

IDH2

Indications and Usage, Dosage and Administration, Clinical Pharmacology, Clinical Studies

Encorafenib (1)

Oncology

BRAF

Indications and Usage, Dosage and Administration, Warnings and Precautions, Adverse Reactions, Use in Specific Populations, Clinical Pharmacology, Clinical Studies, Patient Counseling Information

Encorafenib (2)

Oncology

RAS

Dosage and Administration, Warnings and Precautions, Clinical Studies

Entrectinib (1)

Oncology

ROS1

Indications and Usage, Dosage and Administration, Adverse Reactions, Use in Specific Populations, Clinical Pharmacology, Clinical Studies

Entrectinib (2)

Oncology

NTRK

Indications and Usage, Dosage and Administration, Adverse Reactions, Use in Specific Populations, Clinical Pharmacology, Clinical Studies

Eplontersen

Neurology

TTR

Adverse Reactions, Clinical Pharmacology, Clinical Studies

Erdafitinib (1)

Oncology

FGFR3

Indications and Usage, Dosage and Administration, Adverse Reactions, Clinical Studies, Patient Counseling Information

Erdafitinib (2)

Oncology

CYP2C9

Use in Specific Populations, Clinical Pharmacology

Eribulin (1)

Oncology

ERBB2
(HER2)

Clinical Studies

Eribulin (2)

Oncology

ESR, PGR
(Hormone Receptor)

Clinical Studies

Erlotinib

Oncology

EGFR

Indications and Usage, Dosage and Administration, Adverse Reactions, Clinical Studies

Erythromycin and Sulfisoxazole

Infectious Diseases

G6PD

Precautions

Escitalopram (1)

Psychiatry

CYP2D6

Drug Interactions

Escitalopram (2)

Psychiatry

CYP2C19

Adverse Reactions

Esomeprazole

Gastroenterology

CYP2C19

Drug Interactions, Clinical Pharmacology

Estradiol and Progesterone (1)

Gynecology

PROC

Contraindications

Estradiol and Progesterone (2)

Gynecology

PROS1

Contraindications

Estradiol and Progesterone (3)

Gynecology

SERPINC1
(Antithrombin III)

Contraindications

Estradiol Valerate

Gynecology

ESR, PGR
(Hormone Receptor)

Warnings

Eteplirsen

Neurology

DMD

Indications and Usage, Adverse Reactions, Use in Specific Populations, Clinical Studies

Etrasimod

Gastroenterology

CYP2C9

Drug Interactions, Use in Specific Populations, Clinical Pharmacology

Everolimus (1)

Oncology

ERBB2
(HER2)

Indications and Usage, Dosage and Administration, Warnings and Precautions, Adverse Reactions, Use in Specific Populations, Clinical Pharmacology, Clinical Studies

Everolimus (2)

Oncology

ESR
(Hormone Receptor)

Indications and Usage, Dosage and Administration, Warnings and Precautions, Adverse Reactions, Use in Specific Populations, Clinical Pharmacology, Clinical Studies

Evinacumab-dgnb (1)

Endocrinology

LDLR

Clinical Studies

Evinacumab-dgnb (2)

Endocrinology

Nonspecific
(Homozygous Familial Hypercholesterolemia)

Indication and Usage, Adverse Reactions, Use in Specific Populations, Clinical Pharmacology, Clinical Studies

Evolocumab (1)

Endocrinology

Nonspecific
(Heterozygous Familial Hypercholesterolemia)

Indications and Usage, Dosage and Administration, Adverse Reactions, Use in Specific Populations, Clinical Pharmacology, Clinical Studies

Evolocumab (2)

Endocrinology

Nonspecific
(Homozygous Familial Hypercholesterolemia)

Indications and Usage, Dosage and Administration, Adverse Reactions, Use in Specific Populations, Clinical Pharmacology, Clinical Studies

Exemestane

Oncology

ESR, PGR
(Hormone Receptor)

Indications and Usage, Dosage and Administration, Clinical Studies

Fam-Trastuzumab Deruxtecan-nxki (1)

Oncology

ERBB2
(HER2)

Indications and Usage, Dosage and Administration, Warnings and Precautions, Adverse Reactions, Use in Specific Populations, Clinical Pharmacology, Clinical Studies

Fam-Trastuzumab Deruxtecan-nxki (2)

Oncology

ESR
(Hormone Receptor)

Clinical Studies

Fesoterodine

Urology

CYP2D6

Drug Interactions, Clinical Pharmacology

Fosphenytoin (1)

Neurology

CYP2C9

Warnings and Precautions, Use in Specific Populations, Clinical Pharmacology

Fosphenytoin (2)

Neurology

HLA-B

Warnings and Precautions

Flibanserin (1)

Gynecology

CYP2C9

Clinical Pharmacology

Flibanserin (2)

Gynecology

CYP2C19

Adverse Reactions, Use in Specific Populations, Clinical Pharmacology

Flibanserin (3)

Gynecology

CYP2D6

Clinical Pharmacology

Fluorouracil (1)

Dermatology

DPYD

Contraindications, Warnings

Fluorouracil (2)

Oncology

DPYD

Warnings and Precautions, Clinical Pharmacology, Patient Counseling Information

Fluoxetine

Psychiatry

CYP2D6

Warnings and Precautions, Drug Interactions, Clinical Pharmacology

Flurbiprofen

Rheumatology

CYP2C9

Clinical Pharmacology

Flutamide

Oncology

G6PD

Warnings

Fluvoxamine

Psychiatry

CYP2D6

Drug Interactions

Formoterol (1)

Pulmonary

CYP2D6

Clinical Pharmacology

Formoterol (2)

Pulmonary

CYP2C19

Clinical Pharmacology

Fosdenopterin

Neurology

MOCS1

Indications and Usage, Dosage and Administration, Adverse Reactions, Use in Specific Populations, Clinical Pharmacology, Clinical Studies

Fruquintinib

Oncology

RAS

Indications and Usage, Clinical Studies

Fulvestrant (1)

Oncology

ERBB2
(HER2)

Indications and Usage, Adverse Reactions, Clinical Studies

Fulvestrant (2)

Oncology

ESR, PGR
(Hormone Receptor)

Indications and Usage, Adverse Reactions, Clinical Pharmacology, Clinical Studies

Futibatinib

Oncology

FGFR2

Indications and Usage, Dosage and Administration, Adverse Reactions, Clinical Studies

Galantamine

Neurology

CYP2D6

Clinical Pharmacology

Ganaxolone

Neurology

CDKL5

Indications and Usage, Clinical Studies

Gefitinib (1)

Oncology

EGFR

Indications and Usage, Dosage and Administration, Clinical Studies

Gefitinib (2)

Oncology

CYP2D6

Clinical Pharmacology

Gemtuzumab Ozogamicin

Onoclogy

CD33

Indications and Usage, Dosage and Administration, Adverse Reactions, Clinical Studies

Gentamicin

Infectious Diseases

MT-RNR1

Warnings

Gilteritinib

Oncology

FLT3

Indications and Usage, Dosage and Administration, Clinical Studies

Givosiran

Gastroenterology

CPOX, HMBS, PPOX
(Acute Hepatic Porphyria)

Clinical Studies

Glimepiride

Endocrinology

G6PD

Warnings and Precautions, Adverse Reactions

Glipizide

Endocrinology

G6PD

Precautions

Glyburide

Endocrinology

G6PD

Precautions

Glycerol Phenylbutyrate (1)

Inborn Errors of Metabolism

ASS1, CPS1, OTC
(Urea Cycle Disorders)

Indications and Usage, Adverse Reactions, Clinical Studies

Glycerol Phenylbutyrate (2)

Inborn Errors of Metabolism

NAGS

Indications and Usage

Golodirsen

Neurology

DMD

Indications and Usage, Use in Specific Populations, Clinical Pharmacology, Clinical Studies

Goserelin

Oncology

ESR, PGR
(Hormone Receptor)

Indications and Usage, Clinical Studies

Hydralazine

Cardiology

Nonspecific
(NAT)

Clinical Pharmacology

Hydroxychloroquine

Infectious Diseases

G6PD

Warnings and Precautions, Adverse Reactions

Ibrutinib (1)

Oncology

Chromosome 17p

Indications and Usage, Clinical Studies

Ibrutinib (2)

Oncology

Chromosome 11q

Clinical Studies

Ibrutinib (3)

Oncology

MYD88

Clinical Studies

Iloperidone

Psychiatry

CYP2D6

Dosage and Administration, Warnings and Precautions, Drug Interactions, Clinical Pharmacology

Imatinib (1)

Oncology

KIT

Indications and Usage, Dosage and Administration, Clinical Studies

Imatinib (2)

Oncology

BCR-ABL1
(Philadelphia chromosome)

Indications and Usage, Dosage and Administration, Warnings and Precautions, Adverse Reactions, Use in Specific Populations, Clinical Pharmacology, Clinical Studies

Imatinib (3)

Oncology

PDGFRB

Indications and Usage, Dosage and Administration, Clinical Studies

Imatinib (4)

Oncology

FIP1L1-PDGFRA

Indications and Usage, Dosage and Administration, Clinical Studies

Imipramine

Psychiatry

CYP2D6

Precautions

Inclisiran

Endocrinology

Nonspecific
(Heterozygous Familial Hypercholesterolemia)

Indications and Usage, Clinical Studies

Indacaterol

Pulmonary

UGT1A1

Clinical Pharmacology

Inebilizumab-cdon

Neurology

AQP4

Indications and Usage, Clinical Studies

Inotersen

Neurology

TTR

Adverse Reactions, Clinical Pharmacology

Inotuzumab Ozogamicin

Oncology

BCR-ABL1
(Philadelphia chromosome)

Clinical Studies

Ipilimumab (1)

Oncology

HLA-A

Clinical Studies

Ipilimumab (2)

Oncology

Microsatellite Instability, Mismatch Repair

Indications and Usage, Dosage and Administration, Warnings and Precautions, Adverse Reactions, Use in Specific Populations, Clinical Studies

Ipilimumab (3)

Oncology

CD274
(PD-L1)

Indications and Usage, Dosage and Administration, Use in Specific Populations, Clinical Studies

Ipilimumab (4)

Oncology

ALK

Indications and Usage, Adverse Reactions, Clinical Studies

Ipilimumab (5)

Oncology

EGFR

Indications and Usage, Adverse Reactions, Clinical Studies

Irinotecan

Oncology

UGT1A1

Dosage and Administration, Clinical Pharmacology, Clinical Studies

Isatuximab- irfc (1)

Oncology

Chromosome 17p

Clinical Studies

Isatuximab- irfc (2)

Oncology

Chromosome 4p;14q

Clinical Studies

Isatuximab- irfc (3)

Oncology

Chromosome 14q;16q

Clinical Studies

Isoflurane

Anesthesiology

CACNA1S, RYR1
(Genetic Susceptibility to Malignant Hyperthermia)

Contraindications, Warnings, Clinical Pharmacology

Isoniazid, Pyrazinamide, and Rifampin

Infectious Diseases

Nonspecific
(NAT)

Clinical Pharmacology

Isosorbide Dinitrate

Cardiology

CYB5R

Overdosage

Isosorbide Mononitrate

Cardiology

CYB5R

Overdosage

Ivacaftor

Pulmonary

CFTR

Indications and Usage, Adverse Reactions, Use in Specific Populations, Clinical Pharmacology, Clinical Studies

Ivacaftor and Lumacaftor

Pulmonary

CFTR

Indications and Usage, Adverse Reactions, Use in Specific Populations, Clinical Studies

Ivacaftor and Tezacaftor

Pulmonary

CFTR

Indications and Usage, Adverse Reactions, Use in Specific Populations, Clinical Pharmacology, Clinical Studies

Ivosidenib

Oncology

IDH1

Indications and Usage, Dosage and Administration, Clinical Pharmacology, Clinical Studies

Ixabepilone (1)

Oncology

ERBB2
(HER2)

Clinical Studies

Ixabepilone (2)

Oncology

ESR, PGR
(Hormone Receptor)

Clinical Studies

Lacosamide

Neurology

CYP2C19

Clinical Pharmacology

Lansoprazole

Gastroenterology

CYP2C19

Drug Interactions, Clinical Pharmacology

Lapatinib (1)

Oncology

ERBB2
(HER2)

Indications and Usage, Dosage and Administration, Adverse Reactions, Use in Specific Populations, Clinical Studies

Lapatinib (2)

Oncology

ESR, PGR
(Hormone Receptor)

Indications and Usage, Dosage and Administration, Adverse Reactions, Use in Specific Populations, Clinical Studies

Lapatinib (3)

Oncology

HLA-DQA1

Clinical Pharmacology

Lapatinib (4)

Oncology

HLA-DRB1

Clinical Pharmacology

Larotrectinib

Oncology

NTRK

Indications and Usage, Dosage and Administration, Adverse Reactions, Clinical Studies

Lecanemab-irmb

Neurology

APOE

Boxed Warning, Warnings and Precautions, Clinical Studies, Patient Counseling Information

Ledipasvir and Sofosbuvir

Infectious Diseases

IFNL3
(IL28B)

Clinical Studies

Lenalidomide

Hematology

Chromosome 5q

Boxed Warning, Indications and Usage, Adverse Reactions, Use in Specific Populations, Clinical Studies

Leniolisib (1)

Pulmonary

PIK3CD

Clinical Studies

Leniolisib (2)

Pulmonary

PIK3R1

Clinical Studies

Lenvatinib

Oncology

Microsatellite Instability, Mismatch Repair

Indications and Usage, Adverse Reactions, Clinical Studies

Lesinurad

Rheumatology

CYP2C9

Drug Interactions, Clinical Pharmacology

Letrozole

Oncology

ESR, PGR
(Hormone Receptor)

Indications and Usage, Adverse Reactions, Clinical Studies

Levothyroxine

Endocrinology

Nonspecific (Congenital Hypothyroidism)

Indications and Usage, Warnings and Precautions, Use in Specific Populations

Lidocaine and Prilocaine (1)

Anesthesiology

Nonspecific
(Congenital Methemoglobinemia)

Warnings and Precautions

Lidocaine and Prilocaine (2)

Anesthesiology

G6PD

Warnings and Precautions, Clinical Pharmacology

Lidocaine and Tetracaine (1)

Anesthesiology

G6PD

Warnings and Precautions

Lidocaine and Tetracaine (2)

Anesthesiology

Nonspecific
(Congenital Methemoglobinemia)

Warnings and Precautions

Lofexidine

Anesthesiology

CYP2D6

Use in Specific Populations

Lomitapide

Endocrinology

Nonspecific
(Homozygous Familial Hypercholesterolemia)

Indications and Usage, Warnings and Precautions, Adverse Reactions, Clinical Studies

Lonafarnib (1)

Inborn Errors of Metabolism

LMNA

Indications and Usage, Adverse Reactions, Use in Specific Populations, Clinical Studies

Lonafarnib (2)

Inborn Errors of Metabolism

ZMPSTE24

Indications and Usage, Use in Specific Populations

Lorlatinib (1)

Oncology

ALK

Indications and Usage, Dosage and Administration, Adverse Reactions, Clinical Studies

Lorlatinib (2)

Oncology

ROS1

Adverse Reactions

Lumasiran

Urology

AGXT

Indications and Usage, Adverse Reactions, Use in Specific Populations, Clinical Pharmacology, Clinical Studies

Luspatercept–aamt

Hematology

HBB

Clinical Studies

Lusutrombopag (1)

Hematology

F2
(Prothrombin)

Warnings and Precautions

Lusutrombopag (2)

Hematology

F5
(Factor V Leiden)

Warnings and Precautions

Lusutrombopag (3)

Hematology

PROC

Warnings and Precautions

Lusutrombopag (4)

Hematology

PROS1

Warnings and Precautions

Lusutrombopag (5)

Hematology

SERPINC1
(Antithrombin III)

Warnings and Precautions

Lutetium Lu 177 Dotatate

Oncology

SSTR

Indications and Usage, Adverse Reactions, Use in Specific Populations, Clinical Pharmacology, Clinical Studies

Lutetium Lu 177 Vipivotide Tetraxetan

Oncology

FOLH1
(PSMA)

Indications and Usage, Dosage and Administration, Adverse Reactions, Clinical Studies

Mafenide

Infectious Diseases

G6PD

Warnings, Adverse Reactions

Maralixibat (1)

Gastroenterology

JAG1

Clinical Studies

Maralixibat (2)

Gastroenterology

ABCB4

Clinical Pharmacology, Clinical Studies

Maralixibat (3)

Gastroenterology

ABCB11

Indications and Usage, Clinical Pharmacology, Clinical Studies

Maralixibat (4)

Gastroenterology

ATP8B1

Clinical Pharmacology, Clinical Studies

Maralixibat (5)

Gastroenterology

MYO5B

Clinical Pharmacology, Clinical Studies

Maralixibat (6)

Gastroenterology

TJP2

Clinical Pharmacology, Clinical Studies

Margetuximab-cmkb (1)

Oncology

ERBB2
(HER2)

Indications and Usage, Adverse Reactions, Clinical Pharmacology, Clinical Studies

Margetuximab-cmkb (2)

Oncology

FCGR2A
(CD32A)

Clinical Pharmacology

Margetuximab-cmkb (3)

Oncology

FCGR2B
(CD32B)

Clinical Pharmacology

Margetuximab-cmkb (4)

Oncology

FCGR3A
(CD16A)

Clinical Pharmacology

Mavacamten

Cardiology

CYP2C19

Dosage and Administration, Clinical Pharmacology

Mavorixafor

Hematology

CXCR4

Clinical Studies

Mecasermin

Endocrinology

Nonspecific
(GH)

Indications and Usage, Clinical Studies

Meclizine

Neurology

CYP2D6

Warnings and Precautions

Medroxyprogesterone

Gynecology

ESR
(Hormone Receptor)

Warnings

Meloxicam

Anesthesiology

CYP2C9

Use in Specific Populations, Clinical Pharmacology

Mepivacaine (1)

Anesthesiology

G6PD

Warnings

Mepivacaine (2)

Anesthesiology

Nonspecific
(Congenital Methemoglobinemia)

Warnings

Mepolizumab

Oncology

FIP1L1-PDGFRA

Adverse Reactions, Clinical Studies

Mercaptopurine (1)

Oncology

TPMT

Dosage and Administration, Warnings and Precautions, Adverse Reactions, Clinical Pharmacology

Mercaptopurine (2)

Oncology

NUDT15

Dosage and Administration, Warnings and Precautions, Clinical Pharmacology

Methylene Blue

Hematology

G6PD

Contraindications, Warnings and Precautions

Metoclopramide (1)

Gastroenterology

CYB5R

Use in Specific Populations

Metoclopramide (2)

Gastroenterology

G6PD

Use in Specific Populations, Overdosage

Metoclopramide (3)

Gastroenterology

CYP2D6

Dosage and Administration, Use in Specific Populations, Clinical Pharmacology

Metoprolol

Cardiology

CYP2D6

Clinical Pharmacology

Metreleptin

Endocrinology

LEP

Contraindications

Midostaurin (1)

Oncology

FLT3

Indications and Usage, Dosage and Administration, Adverse Reactions, Clinical Studies

Midostaurin (2)

Oncology

NPM1

Clinical Studies

Midostaurin (3)

Oncology

KIT

Clinical Studies

Migalastat

Inborn Errors of Metabolism

GLA

Indications and Usage, Dosage and Administration, Clinical Pharmacology, Clinical Studies

Mirabegron

Urology

CYP2D6

Clinical Pharmacology

Mirvetuximab Soravtansine-gynx

Oncology

FOLR1

Indications and Usage, Dosage and Administration, Clinical Studies

Mitapivat

Hematology

PKLR

Clinical Studies

Mivacurium

Anesthesiology

BCHE

Warnings, Precautions, Clinical Pharmacology

Mobocertinib

Oncology

EGFR

Indications and Usage, Dosage and Administration, Adverse Reactions, Clinical Studies

Modafinil

Psychiatry

CYP2D6

Clinical Pharmacology

Mycophenolic Acid

Transplantation

HPRT1

Warnings and Precautions

Nalidixic Acid

Infectious Diseases

G6PD

Precautions, Adverse Reactions

Nateglinide

Endocrinology

CYP2C9

Drug Interactions

Nebivolol

Cardiology

CYP2D6

Dosage and Administration, Clinical Pharmacology

Nedosiran

Nephrology

AGXT

Indications and Usage, Adverse Reactions, Use in Specific Populations, Clinical Pharmacology, Clinical Studies

Nefazodone

Psychiatry

CYP2D6

Precautions

Neomycin

Infectious Diseases

MT-RNR1

Warnings

Neratinib (1)

Oncology

ERBB2
(HER2)

Indications and Usage, Adverse Reactions, Clinical Studies

Neratinib (2)

Oncology

ESR, PGR
(Hormone Receptor)

Clinical Studies

Nilotinib (1)

Oncology

BCR-ABL1
(Philadelphia chromosome)

Indications and Usage, Dosage and Administration, Warnings and Precautions, Adverse Reactions, Use in Specific Populations, Clinical Pharmacology, Clinical Studies

Nilotinib (2)

Oncology

UGT1A1

Clinical Pharmacology

Niraparib

Oncology

BRCA (Homologous Recombination Deficiency)

Indications and Usage, Dosage and Administration, Clinical Studies

Nitrofurantoin

Infectious Diseases

G6PD

Warnings, Adverse Reactions

Nirogacestat (1)

Oncology

APC

Clinical Studies

Nirogacestat (2)

Oncology

CTNNB1

Clinical Studies

Nivolumab (1)

Oncology

BRAF

Adverse Reactions, Clinical Studies

Nivolumab (2)

Oncology

CD274
(PD-L1)

Indications and Usage, Dosage and Administration, Use in Specific Populations, Clinical Pharmacology, Clinical Studies

Nivolumab (3)

Oncology

Microsatellite Instability, Mismatch Repair

Indications and Usage, Clinical Studies

Nivolumab (4)

Oncology

EGFR

Indications and Usage, Adverse Reactions, Clinical Studies

Nivolumab (5)

Oncology

ALK

Indications and Usage, Adverse Reactions, Clinical Studies

Nivolumab (6)

Oncology

ERBB2
(HER2)

Adverse Reactions, Clinical Studies

Nivolumab and Relatlimab-rmbw (1)

Oncology

BRAF

Clinical Studies

Nivolumab and Relatlimab-rmbw (2)

Oncology

CD274
(PD-L1)

Clinical Studies

Nivolumab and Relatlimab-rmbw (3)

Oncology

LAG3

Clinical Studies

Nortriptyline

Psychiatry

CYP2D6

Precautions

Nusinersen

Neurology

SMN2

Clinical Pharmacology, Clinical Studies

Obinutuzumab

Oncology

MS4A1
(CD20 antigen)

Clinical Studies

Odevixibat (1)

Gastroenterology

ABCB11

Indications and Usage, Clinical Pharmacology, Clinical Studies

Odevixibat (2)

Gastroenterology

ATP8B1

Indications and Usage, Clinical Pharmacology, Clinical Studies

Odevixibat (3)

Gastroenterology

JAG1

Clinical Studies

Odevixibat (4)

Gastroenterology

NOTCH2

Clinical Studies

Olaparib (1)

Oncology

BRCA

Indications and Usage, Dosage and Administration, Warnings and Precautions, Adverse Reactions, Clinical Studies

Olaparib (2)

Oncology

ERBB2
(HER2)

Indications and Usage, Dosage and Administration, Adverse Reactions, Clinical Studies

Olaparib (3)

Oncology

ESR, PGR
(Hormone Receptor)

Indications and Usage, Clinical Studies

Olaparib (4)

Oncology

BRCA, Genomic Instability (Homologous Recombination Deficiency)

Indications and Usage, Dosage and Administration, Adverse Reactions, Clinical Studies

Olaparib (5)

Oncology

Homologous Recombination Repair

Indications and Usage, Dosage and Administration, Adverse Reactions, Clinical Studies

Olaparib (6)

Oncology

PPP2R2A

Clinical Studies

Olaratumab

Oncology

PDGFRA

Clinical Studies

Oliceridine

Anesthesiology

CYP2D6

Warnings and Precautions, Drug Interactions, Use in Specific Populations, Clinical Pharmacology

Olutasidenib

Oncology

IDH1

Indications and Usage, Dosage and Administration, Adverse Reactions, Use in Specific Populations, Clinical Pharmacology, Clinical Studies

Omacetaxine

Oncology

BCR-ABL1
(Philadelphia chromosome)

Clinical Studies

Ombitasvir, Paritaprevir, and Ritonavir

Infectious Diseases

IFNL3
(IL28B)

Clinical Studies

Omeprazole

Gastroenterology

CYP2C19

Drug Interactions, Clinical Pharmacology

Oxymetazoline and Tetracaine (1)

Anesthesiology

G6PD

Warnings and Precautions

Oxymetazoline and Tetracaine (2)

Anesthesiology

Nonspecific
(Congenital Methemoglobinemia)

Warnings and Precautions

Ondansetron

Gastroenterology

CYP2D6

Clinical Pharmacology

Osimertinib

Oncology

EGFR

Indications and Usage, Dosage and Administration, Adverse Reactions, Use in Specific Populations, Clinical Studies

Ospemifene (1)

Gynecology

CYP2C9

Clinical Pharmacology

Ospemifene (2)

Gynecology

CYP2B6

Clinical Pharmacology

Oxcarbazepine

Neurology

HLA-B

Warnings and Precautions

Palbociclib (1)

Oncology

ESR
(Hormone Receptor)

Indications and Usage, Adverse Reactions, Clinical Studies

Palbociclib (2)

Oncology

ERBB2
(HER2)

Indications and Usage, Adverse Reactions, Clinical Studies

Paliperidone

Psychiatry

CYP2D6

Clinical Pharmacology

Palonosetron

Gastroenterology

CYP2D6

Clinical Pharmacology

Panitumumab (1)

Oncology

EGFR

Adverse Reactions, Clinical Pharmacology, Clinical Studies

Panitumumab (2)

Oncology

RAS

Indications and Usage, Dosage and Administration, Warnings and Precautions, Adverse Reactions, Clinical Studies

Pantoprazole

Gastroenterology

CYP2C19

Clinical Pharmacology

Parathyroid Hormone

Inborn Errors of Metabolism

CASR

Indications and Usage, Clinical Studies

Paroxetine

Psychiatry

CYP2D6

Drug Interactions, Clinical Pharmacology

Patisiran

Neurology

TTR

Adverse Reactions, Clinical Pharmacology, Clinical Studies

Pazopanib (1)

Oncology

UGT1A1

Clinical Pharmacology

Pazopanib (2)

Oncology

HLA-B

Clinical Pharmacology

Peginterferon Alfa-2b

Infectious Diseases

IFNL3
(IL28B)

Clinical Pharmacology

Pegloticase

Rheumatology

G6PD

Boxed Warning, Contraindications, Warnings and Precautions, Adverse Reactions, Patient Counseling Information

Pembrolizumab (1)

Oncology

BRAF

Adverse Reactions, Clinical Studies

Pembrolizumab (2)

Oncology

CD274
(PD-L1)

Indications and Usage, Dosage and Administration, Adverse Reactions, Use in Specific Populations, Clinical Studies

Pembrolizumab (3)

Oncology

Microsatellite Instability, Mismatch Repair

Indications and Usage, Dosage and Administration, Adverse Reactions, Use in Specific Populations, Clinical Studies

Pembrolizumab (4)

Oncology

EGFR

Indications and Usage, Adverse Reactions, Clinical Studies

Pembrolizumab (5)

Oncology

ALK

Indications and Usage, Adverse Reactions, Clinical Studies

Pembrolizumab (6)

Oncology

Tumor Mutational Burden

Indications and Usage, Dosage and Administration, Use in Specific Populations, Clinical Studies

Pembrolizumab (7)

Oncology

ERBB2
(HER2)

Indications and Usage, Adverse Reactions, Clinical Studies

Pemetrexed (1)

Oncology

ALK

Indications and Usage, Adverse Reactions, Clinical Studies

Pemetrexed (2)

Oncology

EGFR

Indications and Usage, Adverse Reactions, Clinical Studies

Pemetrexed (3)

Oncology

CD274
(PD-L1)

Clinical Studies

Pemigatinib (1)

Oncology

FGFR1

Indications and Usage, Dosage and Administration, Adverse Reactions, Use in Specific Populations, Clinical Studies

Pemigatinib (2)

Oncology

FGFR2

Indications and Usage, Dosage and Administration, Clinical Studies

Perphenazine

Psychiatry

CYP2D6

Precautions, Clinical Pharmacology

Pertuzumab (1)

Oncology

ERBB2
(HER2)

Indications and Usage, Dosage and Administration, Warnings and Precautions, Adverse Reactions, Clinical Pharmacology, Clinical Studies

Pertuzumab (2)

Oncology

ESR, PGR
(Hormone Receptor)

Clinical Studies

Phenytoin (1)

Neurology

CYP2C9

Warnings and Precautions, Use in Specific Populations, Clinical Pharmacology

Phenytoin (2)

Neurology

CYP2C19

Clinical Pharmacology

Phenytoin (3)

Neurology

HLA-B

Warnings and Precautions

Pimozide

Psychiatry

CYP2D6

Dosage and Administration, Precautions

Piroxicam

Rheumatology

CYP2C9

Clinical Pharmacology

Pirtobrutinib (1)

Oncology

BTK

Clinical Studies

Pirtobrutinib (2)

Oncology

Chromosome 11q

Clinical Studies

Pirtobrutinib (3)

Oncology

Chromosome 17p

Clinical Studies

Pirtobrutinib (4)

Oncology

IGHV

Clinical Studies

Pirtobrutinib (5)

Oncology

TP53

Clinical Studies

Pitavastatin

Endocrinology

Nonspecific
(Heterozygous Familial Hypercholesterolemia)

Indications and Usage, Adverse Reactions, Use in Specific Populations, Clinical Studies

Pitolisant

Psychiatry

CYP2D6

Dosage and Administration, Use in Specific Populations, Clinical Pharmacology

Plazomicin

Infectious Diseases

MT-RNR1

Warnings and Precautions

Polatuzumab Vedotin-piiq (1)

Oncology

BCL2

Clinical Studies

Polatuzumab Vedotin-piiq (2)

Oncology

BCL6

Clinical Studies

Polatuzumab Vedotin-piiq (3)

Oncology

MYC

Clinical Studies

Ponatinib

Oncology

BCR-ABL1
(Philadelphia chromosome)

Indications and Usage, Dosage and Administration, Warnings and Precautions, Adverse Reactions, Use in Specific Populations, Clinical Studies

Pralsetinib

Oncology

CCDC6-RET, KIF5B-RET, RET

Indications and Usage, Dosage and Administration, Adverse Reactions, Use in Specific Populations, Clinical Pharmacology, Clinical Studies

Prasugrel (1)

Cardiology

CYP2C19

Use in Specific Populations, Clinical Pharmacology, Clinical Studies

Prasugrel (2)

Cardiology

CYP2C9

Use in Specific Populations, Clinical Pharmacology, Clinical Studies

Prasugrel (3)

Cardiology

CYP3A5

Use in Specific Populations, Clinical Pharmacology, Clinical Studies

Prasugrel (4)

Cardiology

CYP2B6

Use in Specific Populations, Clinical Pharmacology, Clinical Studies

Primaquine (1)

Infectious Diseases

G6PD

Contraindications, Warnings, Precautions, Adverse Reactions, Overdosage

Primaquine (2)

Infectious Diseases

CYB5R

Precautions, Adverse Reactions

Probenecid

Rheumatology

G6PD

Adverse Reactions

Procainamide

Cardiology

Nonspecific
(NAT)

Adverse Reactions, Clinical Pharmacology

Propafenone

Cardiology

CYP2D6

Dosage and Administration, Warnings and Precautions, Drug Interactions, Clinical Pharmacology

Propranolol

Cardiology

CYP2D6

Clinical Pharmacology

Protriptyline

Psychiatry

CYP2D6

Precautions

Quinidine

Cardiology

CYP2D6

Precautions

Quinine Sulfate (1)

Infectious Diseases

G6PD

Warnings and Precautions

Quinine Sulfate (2)

Infectious Diseases

CYP2D6

Clinical Pharmacology

Quizartinib

Oncology

FLT3

Indications and Usage, Dosage and Administration, Warnings and Precautions, Adverse Reactions, Clinical Studies

Rabeprazole

Gastroenterology

CYP2C19

Drug Interactions, Clinical Pharmacology

Raloxifene

Oncology

ESR
(Hormone Receptor)

Clinical Studies

Raltegravir

Infectious Diseases

UGT1A1

Clinical Pharmacology

Ramucirumab (1)

Oncology

EGFR

Indications and Usage, Dosage and Administration, Adverse Reactions, Clinical Studies

Ramucirumab (2)

Oncology

RAS

Clinical Studies

Rasburicase (1)

Oncology

G6PD

Boxed Warning, Contraindications, Warnings and Precautions

Rasburicase (2)

Oncology

CYB5R

Boxed Warning, Contraindications, Warnings and Precautions

Ravulizumab-cwvz (1)

Neurology

ACHR

Indications and Usage, Clinical Studies

Ravulizumab-cwvz (2)

Neurology

AQP4

Indications and Usage, Clinical Studies

Regorafenib

Oncology

RAS

Indications and Usage, Clinical Studies

Repotrectinib (1)

Oncology

ROS1

Indications and Usage, Dosage and Administration, Adverse Reactions, Use in Specific Populations, Clinical Studies

Repotrectinib (2)

Oncology

NTRK

Indications and Usage, Dosage and Administration, Adverse Reactions, Use in Specific Populations, Clinical Studies

Resmetirom

Gastroenterology

ABCG2

Clinical Pharmacology

Ribociclib (1)

Oncology

ESR, PGR (Hormone Receptor)

Indications and Usage, Adverse Reactions, Clinical Studies

Ribociclib (2)

Oncology

ERBB2
(HER2)

Indications and Usage, Adverse Reactions, Clinical Studies

Rimegepant

Neurology

CYP2C9

Clinical Pharmacology

Risdiplam

Neurology

SMN1, SMN2

Clinical Studies

Risperidone

Psychiatry

CYP2D6

Clinical Pharmacology

Rituximab

Oncology

MS4A1
(CD20 antigen)

Indications and Usage, Dosage and Administration, Adverse Reactions, Use in Specific Populations, Clinical Studies

Rivaroxaban

Cardiology

F5
(Factor V Leiden)

Clinical Studies

Ropeginterferon Alfa-2b-njft

Hematology

JAK2

Clinical Pharmacology, Clinical Studies

Ropivacaine (1)

Anesthesiology

G6PD

Warnings

Ropivacaine (2)

Anesthesiology

Nonspecific
(Congenital Methemoglobinemia)

Warnings

Rosuvastatin

Endocrinology

SLCO1B1

Clinical Pharmacology

Rozanolixizumab-noli (1)

Neurology

ACHR

Indications and Usage, Clinical Pharmacology, Clinical Studies

Rozanolixizumab-noli (2)

Neurology

MUSK

Indications and Usage, Clinical Pharmacology, Clinical Studies

Rucaparib (1)

Oncology

BRCA

Indications and Usage, Dosage and Administration, Adverse Reactions, Clinical Studies

Rucaparib (2)

Oncology

CYP2D6

Clinical Pharmacology

Rucaparib (3)

Oncology

CYP1A2

Clinical Pharmacology

Rucaparib (4)

Oncology

BRCA, Loss of Heterozygosity (Homologous Recombination Deficiency)

Warnings and Precautions, Adverse Reactions, Clinical Studies

Sacituzumab Govitecan-hziy (1)

Oncology

UGT1A1

Warnings and Precautions, Clinical Pharmacology

Sacituzumab Govitecan-hziy (2)

Oncology

BRCA

Clinical Studies

Sacituzumab Govitecan-hziy (3)

Oncology

ESR
(Hormone Receptor)

Indications and Usage, Adverse Reactions, Use in Specific Populations, Clinical Studies

Sacituzumab Govitecan-hziy (4)

Oncology

ERBB2
(HER2)

Indications and Usage, Adverse Reactions, Use in Specific Populations, Clinical Studies

Sacrosidase

Inborn Errors of Metabolism

Nonspecific
(Congenital Sucrase-Isomaltase Deficiency)

Indications and Usage, Adverse Reactions, Clinical Pharmacology

Satralizumab-mwge

Neurology

AQP4

Indications and Usage, Adverse Reactions, Clinical Studies

Selpercatinib

Oncology

RET

Indications and Usage, Dosage and Administration, Adverse Reactions, Use in Specific Populations, Clinical Studies

Setmelanotide (1)

Endocrinology

LEPR

Indications and Usage, Dosage and Administration, Adverse Reactions, Use in Specific Populations, Clinical Studies

Setmelanotide (2)

Endocrinology

PCSK1

Indications and Usage, Dosage and Administration, Adverse Reactions, Use in Specific Populations, Clinical Studies

Setmelanotide (3)

Endocrinology

POMC

Indications and Usage, Dosage and Administration, Adverse Reactions, Use in Specific Populations, Clinical Studies

Sevoflurane

Anesthesiology

CACNA1S, RYR1
(Genetic Susceptibility to Malignant Hyperthermia)

Contraindications, Warnings, Clinical Pharmacology

Simeprevir

Infectious Diseases

IFNL3
(IL28B)

Clinical Pharmacology, Clinical Studies

Siponimod

Neurology

CYP2C9

Dosage and Administration, Contraindications, Drug Interactions, Use in Specific Populations, Clinical Pharmacology

Sodium Nitrite (1)

Toxicology

G6PD

Warnings and Precautions

Sodium Nitrite (2)

Toxicology

Nonspecific
(Congenital Methemoglobinemia)

Boxed Warning, Warnings and Precautions

Sodium Oxybate

Neurology

ALDH5A1
(Succinic Semialdehyde Dehydrogenase Deficiency)

Contraindications

Sodium Phenylbutyrate

Inborn Errors of Metabolism

ASS1, CPS1, OTC
(Urea Cycle Disorders)

Indications and Usage, Dosage and Administration, Adverse Reactions, Clinical Pharmacology

Sofosbuvir

Infectious Diseases

IFNL3
(IL28B)

Clinical Studies

Sofosbuvir and Velpatasvir

Infectious Diseases

IFNL3
(IL28B)

Clinical Studies

Sofosbuvir, Velpatasvir, and Voxilaprevir

Infectious Diseases

IFNL3
(IL28B)

Clinical Studies

Sotorasib

Oncology

KRAS

Indication and Usage, Dosage and Administration, Adverse Reactions, Clinical Pharmacology, Clinical Studies

Streptomycin

Infectious Diseases

MT-RNR1

Warnings

Succimer

Hematology

G6PD

Clinical Pharmacology

Succinylcholine (1)

Anesthesiology

BCHE

Warnings, Precautions

Succinylcholine (2)

Anesthesiology

CACNA1S, RYR1
(Genetic Susceptibility to Malignant Hyperthermia)

Boxed Warning, Contraindications, Warnings, Precautions, Adverse Reactions, Clinical Pharmacology

Sulfadiazine

Infectious Diseases

G6PD

Warnings

Sulfamethoxazole and Trimethoprim (1)

Infectious Diseases

G6PD

Precautions

Sulfamethoxazole and Trimethoprim (2)

Infectious Diseases

Nonspecific
(NAT)

Precautions

Sulfasalazine (1)

Gastroenterology

G6PD

Precautions

Sulfasalazine (2)

Gastroenterology

Nonspecific
(NAT)

Clinical Pharmacology

Synthetic Conjugated Estrogens, A (1)

Gynecology

PROC

Contraindications

Synthetic Conjugated Estrogens, A (2)

Gynecology

PROS1

Contraindications

Synthetic Conjugated Estrogens, A (3)

Gynecology

SERPINC1
(Antithrombin III)

Contraindications

Tafamidis

Cardiology

TTR

Clinical Pharmacology, Clinical Studies

Tafenoquine

Infectious Diseases

G6PD

Dosage and Administration, Contraindications, Warnings and Precautions, Use in Specific Populations, Patient Counseling Information

Talazoparib (1)

Oncology

BRCA

Indications and Usage, Dosage and Administration, Adverse Reactions, Clinical Studies

Talazoparib (2)

Oncology

ERBB2
(HER2)

Indications and Usage, Adverse Reactions, Clinical Studies

Talazoparib (3)

Oncology

Homologous Recombination Repair

Indications and Usage, Dosage and Administrations, Adverse Reactions, Drug Interactions, Clinical Studies

Tamoxifen (1)

Oncology

ESR, PGR
(Hormone Receptor)

Indications and Usage, Adverse Reactions, Clinical Pharmacology, Clinical Studies

Tamoxifen (2)

Oncology

F5
(Factor V Leiden)

Warnings and Precautions

Tamoxifen (3)

Oncology

F2
(Prothrombin)

Warnings and Precautions

Tamoxifen (4)

Oncology

CYP2D6

Clinical Pharmacology

Tamsulosin

Urology

CYP2D6

Warnings and Precautions, Adverse Interactions, Clinical Pharmacology

Tebentafusp-tebn

Oncology

HLA-A

Indications and Usage, Dosage and Administration, Clinical Studies

Teclistamab-cqyv (1)

Oncology

Chromosome 17p

Clinical Studies

Teclistamab-cqyv (2)

Oncology

Chromosome 4p;14q

Clinical Studies

Teclistamab-cqyv (3)

Oncology

Chromosome 14q;16q

Clinical Studies

Telaprevir

Infectious Diseases

IFNL3
(IL28B)

Clinical Pharmacology, Clinical Studies

Tepotinib (1)

Oncology

ALK

Clinical Studies

Tepotinib (2)

Oncology

EGFR

Clinical Studies

Tepotinib (3)

Oncology

MET

Indications and Usage, Dosage and Administration, Adverse Reactions, Use in Specific Populations, Clinical Studies

Tetrabenazine

Neurology

CYP2D6

Dosage and Administration, Warnings and Precautions, Use in Specific Populations, Clinical Pharmacology

Thioguanine (1)

Oncology

TPMT

Dosage and Administration, Warnings, Precautions, Clinical Pharmacology

Thioguanine (2)

Oncology

NUDT15

Dosage and Administration, Warnings, Precautions, Clinical Pharmacology

Thioridazine

Psychiatry

CYP2D6

Contraindications, Warnings, Precautions

Ticagrelor

Cardiology

CYP2C19

Clinical Pharmacology

Tipiracil and Trifluridine (1)

Oncology

ERBB2
(HER2)

Indications and Usage, Adverse Reactions, Clinical Studies

Tipiracil and Trifluridine (2)

Oncology

RAS

Indications and Usage, Clinical Studies

Tislelizumab-jsgr

Oncology

CD274
(PD-L1)

Clinical Studies

Tobramycin

Infectious Diseases

MT-RNR1

Warnings and Precautions

Tofersen

Oncology

SOD1

Indications and Usage, Use in Specific Populations, Clinical Studies

Tolazamide

Endocrinology

G6PD

Precautions

Tolbutamide

Endocrinology

G6PD

Precautions

Tolterodine

Urology

CYP2D6

Warnings and Precautions, Drug Interactions, Clinical Pharmacology

Toremifene

Oncology

ESR
(Hormone Receptor)

Indications and Usage, Clinical Studies

Tovorafenib

Oncology

BRAF

Indications and Usage, Dosage and Administration, Warnings and Precautions, Adverse Reactions, Use in Specific Populations, Clinical Studies

Tramadol

Anesthesiology

CYP2D6

Boxed Warning, Warnings and Precautions, Use in Specific Populations, Clinical Pharmacology, Patient Counseling Information

Trametinib (1)

Oncology

BRAF

Indications and Usage, Dosage and Administration, Adverse Reactions, Use in Specific Populations, Clinical Pharmacology, Clinical Studies

Trametinib (2)

Oncology

G6PD

Adverse Reactions

Trametinib (3)

Oncology

RAS

Warnings and Precautions

Trastuzumab (1)

Oncology

ERBB2
(HER2)

Indications and Usage, Dosage and Administration, Clinical Pharmacology, Clinical Studies

Trastuzumab (2)

Oncology

ESR, PGR
(Hormone Receptor)

Clinical Studies

Tretinoin

Oncology

PML-RARA

Indications and Usage, Dosage and Administration, Warnings and Precautions, Patient Counseling Information

Triheptanoin

Inborn Errors of Metabolism

ACADVL, CPT2, HADHA, HADHB (Long-Chain Fatty Acid Oxidation Disorders)

Indications and Usage, Clinical Studies

Tremelimumab-actl (1)

Oncology

ALK

Indications and Usage, Clinical Studies

Tremelimumab-actl (2)

Oncology

EGFR

Indications and Usage, Clinical Studies

Tremelimumab-actl (3)

Oncology

CD274
(PD-L1)

Clinical Studies

Trimipramine

Psychiatry

CYP2D6

Precautions

Trofinetide

Neurology

MECP2

Clinical Studies

Tucatinib (1)

Oncology

ERBB2
(HER2)

Indications and Usage, Dosage and Administration, Adverse Reactions, Clinical Studies

Tucatinib (2)

Oncology

Microsatellite Instability, Mismatch Repair

Indications and Usage, Dosage and Administration, Adverse Reactions, Clinical Studies

Tucatinib (3)

Oncology

RAS

Clinical Studies

Umeclidinium

Pulmonary

CYP2D6

Clinical Pharmacology

Upadacitinib

Rheumatology

CYP2D6

Clinical Pharmacology

Ustekinumab

Dermatology and Gastroenterology

IL12A, IL12B, IL23A

Warnings and Precautions

Valbenazine

Neurology

CYP2D6

Dosage and Administration, Warnings and Precautions, Use in Specific Populations, Clinical Pharmacology

Valproic Acid (1)

Neurology

POLG

Boxed Warning, Contraindications, Warnings and Precautions

Valproic Acid (2)

Neurology

Nonspecific
(Urea Cycle Disorders)

Contraindications, Warnings and Precautions

Vemurafenib (1)

Oncology

BRAF

Indications and Usage, Dosage and Administration, Warnings and Precautions, Adverse Reactions, Use in Specific Populations, Clinical Pharmacology, Clinical Studies, Patient Counseling Information

Vemurafenib (2)

Oncology

RAS

Warnings and Precautions, Adverse Reactions

Venetoclax (1)

Oncology

Chromosome 17p

Clinical Studies

Venetoclax (2)

Oncology

Chromosome 11q

Clinical Studies