KEGG BRITE Database (original) (raw)

Functional Hierarchies

KEGG BRITE is a collection of hierarchical classification systems capturing functional hierarchies of various biological objects, especially those represented as KEGG objects. They are represented as BRITE hierarchy files, also called hierarchical text (htext) files, which are supplemented by BRITE table files using html tables. BRITE hierarchy files may be associated with binary relation files containing various attributes of KEGG objects. The BRITE browser allows selection of such binary relations shown in the left panel for display as additional columns in the hierarchy. BRITE table files focus more on such multi-column attributes rather than hierarchy relationships. In comparison to KEGG PATHWAY, which is limited to molecular interactions and reactions, KEGG BRITE incorporates many different types of relationships including:

The brite hierarchy viewer linked from this page is a part of KEGG Web Apps and contains features of KEGG mapping.

Brite Identifiers

Each brite hierarchy/table is identified by the combination of 2-4 letter prefix code and 5 digit number (see KEGG Identifier). The prefix has the following meaning:

non-gene/protein reference hierarchy or table

non-gene/protein reference hierarchy or table in Japanese

gene/protein reference hiearchy for KO expansion

organism-specific hierarchy generated by converting KOs to gene identifiers

Pathway and Brite

1. Genes and Proteins

1.1 Orthologs and modules (K/M nubmers)

1.2 Protein families: metabolism (K numbers)

1.3 Protein families: genetic information processing (K numbers)

1.4 Protein families: signaling and cellular processes (K numbers)

1.5 Viral protein families (K numbers)

1.6 RNA family (K numbers)

1.7 Annotation guide

1.8 Sequence data collection

2. Compounds and Reactions

2.1 Compounds (C numbers)

2.2 Glycans (G numbers)

2.3 Reactions (R/RC numbers)

3. Drugs

3.1 Drug classifications (D numbers)

3.2 Drug information (D numbers)

08308

(table) Narcotics and psychotropics in Japan

4. Diseases

4.1 Human diseases (H numbers)

4.2 Disease genes and markers

5. Organisms and Viruses

5.1 Taxonomy

5.2 Organism information

Codes and Abbreviations

Last updated: September 25, 2024