Ppia gene cDNA ORF clone, Rattus norvegicus(Norway rat) (original ) (raw )
Summary
Gene Symbol
Ppia
Entrez Gene ID
25518
Full Name
peptidylprolyl isomerase A (cyclophilin A)
Synonyms
CYCA,CyP-A
General protein information
Preferred Namespeptidylprolyl isomerase A (cyclophilin A) Namespeptidyl-prolyl cis-trans isomerase APPIase Acyclophilin Acyclosporin A-binding proteinp1B15p31rotamase A
Gene Type
protein-coding
Organism
Rattus norvegicus(Norway rat)
Genome
Chromosome: 14 Map Location: 14q21
Summary
may play a role in protein folding or intracellular protein transport [RGD, Feb 2006].
mRNA and Protein(s)
mRNA
Protein
Name
NM_017101.1
NP_058797.1
peptidyl-prolyl cis-trans isomerase A
XM_017599085.1
XP_017454574.1
peptidyl-prolyl cis-trans isomerase A isoform X1
Pathways from BioSystems
Homologies
Bos taurus (cattle)
LOC100337215
XP_002690561.1
Mus musculus (house mouse)
Ppia
NP_032933.1
Rattus norvegicus (Norway rat)
LOC100360977
XP_006250863.1
Caenorhabditis elegans (roundworm)
cyn-1
NP_506561.1
Kluyveromyces lactis
KLLA0B04565g
XP_451736.1
Arabidopsis thaliana (thale cress)
ROC2
NP_191166.1
Xenopus tropicalis (tropical clawed frog)
LOC100496569
XP_002932593.1
Homo sapiens (human)
PPIA
NP_066953.1
Pan troglodytes (chimpanzee)
PPIA
XP_003951049.1
Rattus norvegicus (Norway rat)
Ppia
NP_058797.1
Oryza sativa (rice)
Os09g0571400
NP_001063993.1
Canis lupus familiaris (dog)
PPIA
XP_532723.2
Eremothecium gossypii
AGOS_AER156C
NP_985014.1
PPIA
NP_001027981.1
Rattus norvegicus (Norway rat)
LOC100911252
XP_006236184.1
Gallus gallus (chicken)
PPIA
NP_001159798.1
Danio rerio (zebrafish)
ppiaa
NP_997923.1
Saccharomyces cerevisiae (baker's yeast)
CPR3
NP_013633.1
Gene Ontology
Bibliography
Related articles in PubMedOxidized Low-Density Lipoprotein-Induced Cyclophilin A Secretion Requires ROCK-Dependent Diphosphorylation of Myosin Light Chain. Su Z, Lin R, Chen Y, Shu X, Zhang H, Liang S, Nie R, Wang J, Xie S Journal of vascular research53(3-4)206-215(2016)Diet induced obesity in rats reduces NHE3 and Na(+) /K(+) -ATPase expression in the kidney. Briffa JF, Grinfeld E, Jenkin KA, Mathai ML, Poronnik P, McAinch AJ, Hryciw DH Clinical and experimental pharmacology & physiology42(10)1118-26(2015 Oct)Pancreatic acinar cells-derived cyclophilin A promotes pancreatic damage by activating NF-?B pathway in experimental pancreatitis. Yu G, Wan R, Hu Y, Ni J, Yin G, Xing M, Shen J, Tang M, Chen C, Fan Y, Xiao W, Zhao Y, Wang X, Hu G Biochemical and biophysical research communications444(1)75-80(2014 Jan)GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following Ppia gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ppia cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
161121181241301361421481
ATGGTCAACC CCACCGTGTT CTTCGACATC ACGGCTGATG GCGAGCCCTT GGGTCGCGTC TGCTTCGAGC TGTTTGCAGA CAAAGTTCCA AAGACAGCAG AAAACTTTCG TGCTCTGAGC ACTGGGGAGA AAGGATTTGG CTATAAGGGT TCCTCCTTTC ACAGAATTAT TCCAGGATTC ATGTGCCAGG GTGGTGACTT CACACGCCAT AATGGCACTG GTGGCAAGTC CATCTACGGA GAGAAATTTG AGGATGAGAA CTTCATCCTG AAGCATACAG GTCCTGGCAT CTTGTCCATG GCAAATGCTG GACCAAACAC AAATGGTTCC CAGTTTTTTA TCTGCACTGC CAAGACTGAG TGGCTGGATG GCAAGCATGT GGTCTTTGGG AAGGTGAAAG AAGGCATGAG CATTGTGGAA GCCATGGAGC GTTTTGGGTC CAGGAATGGC AAGACCAGCA AGAAGATCAC CATCTCCGAC TGTGGACAAC TCTAA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq
NP_058797.1
---------------
------------
CDS
43..537
Translation
Target ORF information: RefSeq Version NM_017101.1 Organism Rattus norvegicus(Norway rat) Definition Rattus norvegicus peptidylprolyl isomerase A (Ppia), mRNA. Target ORF information: Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK
NM_017101.1
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
-----------------------------------------------------------------
ORF Insert Sequence:
161121181241301361421481
ATGGTCAACC CCACCGTGTT CTTCGACATC ACGGCTGATG GCGAGCCCTT GGGTCGCGTC TGCTTCGAGC TGTTTGCAGA CAAAGTTCCA AAGACAGCAG AAAACTTTCG TGCTCTGAGC ACTGGGGAGA AAGGATTTGG CTATAAGGGT TCCTCCTTTC ACAGAATTAT TCCAGGATTC ATGTGCCAGG GTGGTGACTT CACACGCCAT AATGGCACTG GTGGCAAGTC CATCTACGGA GAGAAATTTG AGGATGAGAA CTTCATCCTG AAGCATACAG GTCCTGGCAT CTTGTCCATG GCAAATGCTG GACCAAACAC AAATGGTTCC CAGTTTTTTA TCTGCACTGC CAAGACTGAG TGGCTGGATG GCAAGCATGT GGTCTTTGGG AAGGTGAAAG AAGGCATGAG CATTGTGGAA GCCATGGAGC GTTTTGGGTC CAGGAATGGC AAGACCAGCA AGAAGATCAC CATCTCCGAC TGTGGACAAC TCTAA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
161121181241301
ATGTGCCAGG GTGGTGACTT CACACGCCAT AATGGCACTG GTGGCAAGTC CATCTACGGA GAGAAATTTG AGGATGAGAA CTTCATCCTG AAGCATACAG GTCCTGGCAT CTTGTCCATG GCAAATGCTG GACCAAACAC AAATGGTTCC CAGTTTTTTA TCTGCACTGC CAAGACTGAG TGGCTGGATG GCAAGCATGT GGTCTTTGGG AAGGTGAAAG AAGGCATGAG CATTGTGGAA GCCATGGAGC GTTTTGGGTC CAGGAATGGC AAGACCAGCA AGAAGATCAC CATCTCCGAC TGTGGACAAC TCTAA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq
XP_017454574.1
---------------
---------------
CDS
192..506
Translation
Target ORF information: RefSeq Version XM_017599085.1 Organism Rattus norvegicus(Norway rat) Definition Rattus norvegicus peptidylprolyl isomerase A (cyclophilin A) (Ppia), transcript variant X1, mRNA. Target ORF information: Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK
XM_017599085.1
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
--------------------------------------------------------------------
ORF Insert Sequence:
161121181241301
ATGTGCCAGG GTGGTGACTT CACACGCCAT AATGGCACTG GTGGCAAGTC CATCTACGGA GAGAAATTTG AGGATGAGAA CTTCATCCTG AAGCATACAG GTCCTGGCAT CTTGTCCATG GCAAATGCTG GACCAAACAC AAATGGTTCC CAGTTTTTTA TCTGCACTGC CAAGACTGAG TGGCTGGATG GCAAGCATGT GGTCTTTGGG AAGGTGAAAG AAGGCATGAG CATTGTGGAA GCCATGGAGC GTTTTGGGTC CAGGAATGGC AAGACCAGCA AGAAGATCAC CATCTCCGAC TGTGGACAAC TCTAA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Pancreatic acinar cells-derived cyclophilin A promotes pancreatic damage by activating NF-?B pathway in experimental pancreatitis. Biochemical and biophysical research communications444(1)75-80(2014 Jan) Yu G,Wan R,Hu Y,Ni J,Yin G,Xing M,Shen J,Tang M,Chen C,Fan Y,Xiao W,Zhao Y,Wang X,Hu G
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