HOLE program homepage (original) (raw)

HOLE is a program that allows the analysis and visualisation of the pore dimensions of the holes through molecular structures of ion channelsSmart et al., 1996. It was written byOliver Smartwhile a post doc and independent research fellow at Birkbeck College with the assistance of several students:Guy Coates,Joe Neduvelil, Valeriu Niculae and Xiaonan Wang.

The first application of HOLE was to analyse the pore dimensions of gramicidin ASmart et al., 1993working withJulia Goodfellow andBonnie Wallace. Although it was written over 20 years ago, HOLE remains in demand and its main publications have been cited over 800 times.