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Welcome to IMB! We are a modern research centre that brings together leading scientists from all over the world. Our researchers tackle ambitious projects at the interface of epigenetics, genome stability, ageing & RNA biology.

• About usWho we are, where we are & what we do...
• ResearchOur scientists & what they are working on...
• Core FacilitiesState-of-the-art technologies & services...
• Students & PostdocsTraining programmes we offer junior researchers...
• Seminars & EventsConferences, meetings, workshops & more...
• CareersCurrent opportunities at IMB...

Upcoming Events

• 21 Nov - 22 Nov 2024Workshop | IMB Workshop2024 CHA workshopSteve Horvath, Altos Labs, Cambridge, USA Luigi Ferrucci, National Institute of Aging, USA

• Oct 2024 | Open Biol | Keller ValsecchiSex as a biological variable in ageing: insights and perspectives on the molecular and cellular…

• Oct 2024 | Mol Cell | RoukosType II topoisomerases shape multi-scale 3D chromatin folding in regions of positive supercoils.

• Sep 2024 | Nat Cell Biol | PadekenFasting shapes chromatin architecture through an mTOR/RNA Pol I axis.

• Sep 2024 | Trends Genet | Keller ValsecchiDosage compensation in non-model insects - progress and perspectives.

• Aug 2024 | Cell | Niehrs5-Formylcytosine is an activating epigenetic mark for RNA Pol III during zygotic reprogramming.

• Aug 2024 | Aging Cell | SchweigerPremature cognitive decline in a mouse model of tuberous sclerosis.

• Aug 2024 | Nucleic Acids Res | KettingMUT-7 exoribonuclease activity and localization are mediated by an ancient domain.

• Aug 2024 | Nucleic Acids Res | LuckHistone variant macroH2A1 regulates synchronous firing of replication origins in the inactive X…

• Aug 2024 | Arch Public Health | TüscherChange of self-rated physical health predicts mortality in aging individuals: results of a…

• [Aug 2024 | _Bioessays_ | NiehrsAn "R-spondin code" for multimodal signaling ON-OFF states.](/publication/an-r-spondin-code-for-multimodal-signaling-on-off-states "An "R-spondin code" for multimodal signaling ON-OFF states.")

Joint Research Initiatives

• A centre for basic & clinical research on ageing & age-related diseasewith Mainz University & its Medical Center, the Leibniz Institute for Resilience Research & TRON
• A joint initiative on the mechanisms underlying robustness & longevitywith groups at Mainz University
• A joint PhD programme to discover new ways to understand & treat age-related diseaseswith Mainz University & its Medical Center
• The largest network on DNA repair & genome stability in Germanywith groups in Mainz, Darmstadt, Frankfurt & Munich
• An initiative bridging the polymer & life sciences to understand biological processes such as ageingwith Mainz University, its Medical Center & the Max Planck Institute for Polymer Research
• IMB’s flagship PhD training programme on epigenetics, genome stability & ageingwith Mainz University & its Medical Center
• A DFG-funded PhD programme on how RNA processes contribute to robustness & resiliencewith groups from Mainz University & its Medical Center
• A DFG-funded PhD programme on the evolution of gene regulatory networks underlying phenotype & lifespanwith Mainz University’s Faculty of Biology
• IMB's summer school on epigenetics & genome stability in health, ageing & disease, for Master & undergraduate studentswith Mainz University's Faculty of Biology