Nature (original) (raw)
- ArticleOpen Access10 Dec 2025
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Current Issue11 Dec 2025
Latest Reviews & Analysis
A giant catalogue of microscopic species across Denmark
The Microflora Danica project has catalogued the microbial diversity of environmental habitats across Denmark and established an improved taxonomic reference database. As well as providing a special record of nitrogen-oxidizing microorganisms, the data set serves as a national baseline for tracking future microbial responses to factors such as land-use change and global warming.
A simple slipknot for precise force control
The tension of conventional surgical sutures can affect wound healing and is dependent on the surgeon’s experience. Imaging and simulations reveal that slipknots can reproducibly store and release force, enabling precise and consistent surgical knotting without the need for electronic sensors or specialized equipment.
Latest Research articles
- ArticleOpen Access10 Dec 2025
Quantifying grain boundary deformation mechanisms in small-grained metals
Experimental observations in small-grained polycrystals suggest a new concept of considering metallic grain boundaries not as defects but as separate defect-containing lattices, providing a potential explanation for the deformation behaviour of nanocrystalline metals.
- Romain Gautier
- Frédéric Mompiou
- Marc Legros
Article10 Dec 2025 
Gene-drive-capable mosquitoes suppress patient-derived malaria in Tanzania
Engineering of local Anopheles gambiae under containment enables the generation of a transgenic strain equipped with non-autonomous gene drive capabilities that robustly inhibits genetically diverse Plasmodium falciparum isolates obtained from naturally infected children.
- Tibebu Habtewold
- Dickson Wilson Lwetoijera
- George K. Christophides
ArticleOpen Access10 Dec 2025 
Erythropoietin receptor on cDC1s dictates immune tolerance
The tolerogenic activity of type 1 conventional dendritic cells (cDC1s) is determined by EPOR, which is preferentially expressed in cDC1s and induces antigen-specific FOXP3-expressing regulatory T cells.
- Xiangyue Zhang
- Christopher S. McGinnis
- Edgar G. Engleman
Article10 Dec 2025 
Human gut M cells resemble dendritic cells and present gluten antigen
An intestinal organoid model recapitulates human microfold (M) cell function and transcriptomic profiling and biochemical assays demonstrate that M cells uptake and present antigens to the immune system via the class II major histocompatibility complex.
- Daisong Wang
- Sangho Lim
- Hans Clevers
ArticleOpen Access10 Dec 2025
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How Trump 2.0 is reshaping science
Since US President Donald Trump took office in January 2025, his team has made major changes to the federal government that have disrupted research and research institutions in the United States and beyond.
Collection 26 Feb 2025
