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| Nature Medicine (original) (raw)

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Economics, equity and avoidable mortality

Two new studies characterize the unequal global burden of avoidable mortality and the economic value of reducing it — providing evidence to support targeted investment in health and longevity.

Perioperative immunotherapy for bladder cancer

In the NIAGARA trial, the addition of perioperative durvalumab to standard treatment for muscle-invasive bladder cancer improved event-free and overall survival, marking a new treatment option for this condition.

Cell therapy for neurological disorders

This Review summarizes the state of clinical research on cell replacement therapy for neurological conditions, and discusses the challenges facing the field, from immunosuppression and therapeutic delivery to cost issues.

A chatbot changes the minds of conspiracy theorists

A study of over 2,000 people shows that interacting with a large language model reduced belief in conspiracy theories — including some related to COVID-19 — by providing tailored, one-on-one interactions and compelling evidence.

How to make cardiology clinical trials more inclusive

Cardiology trials continue to under-represent certain population groups relative to disease distribution; this Perspective outlines strategies to foster representativeness and create a research enterprise that meets the needs of people living with cardiovascular disease.

Computational brain models map diversity embedded in aging and dementia

This study explored how diverse factors including neurocognitive disorders, socioeconomic inequalities, pollution and gender disparities influence brain aging in underserved populations (groups with limited access to essential services such as healthcare and education). Using deep learning on EEG and fMRI data, we identified brain-age gaps as key markers of accelerated brain aging and their connections to macrosocial determinants of health.
Research Briefing10 Oct 2024

People with cardiac pacemakers require multidisciplinary care

Echocardiographic screening during routine pacemaker checkups identifies pacing-induced cardiomyopathy in more than one-third of patients, requiring multidisciplinary, guideline-directed follow-up care.