Nature Reviews Molecular Cell Biology (original) (raw)
Featured
- Review Article21 May 2024
The cell biology of ferroptosis
Ferroptosis is a non-apoptotic, iron-dependent cell death mechanism driven by plasma membrane lipid peroxidation and subsequent plasma membrane rupture. Various cellular compartments and organelles contribute to regulating susceptibility to ferroptosis. This regulation involves a plethora of mechanisms centred on iron metabolism and storage, lipid metabolism, and redox balance.
- Scott J. Dixon
- James A. Olzmann
Review Article16 Feb 2024
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