The cerebral vasculature in dementia pugilistica (original) (raw)

Abstract

The brains of 22 ex-boxers were examined histologically to determine the frequency of recent or old haemorrhage. Four boxers had died from an acute intracerebral bleed, usually soon after a boxing bout. Seven of the other 18 showed evidence of previous perivascular haemorrhage, as detected by Perls' ferrocyanide test for iron, and a similar number showed minor degrees of meningeal or subpial siderosis, consistent with previous meningeal bleeding; cerebellar siderosis was present in six cases. Seventeen of the 22 boxers showed evidence of recent or past haemorrhage. Control material showed an incidence of 11% for perivascular iron deposition and only 4% for minor degrees of meningeal siderosis.

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Selected References

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  1. Adams C. W. Perivascular iron deposition and other vascular damage in multiple sclerosis. J Neurol Neurosurg Psychiatry. 1988 Feb;51(2):260–265. doi: 10.1136/jnnp.51.2.260. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Corsellis J. A., Bruton C. J., Freeman-Browne D. The aftermath of boxing. Psychol Med. 1973 Aug;3(3):270–303. doi: 10.1017/s0033291700049588. [DOI] [PubMed] [Google Scholar]
  3. Hughes J. T., Oppenheimer D. R. Superficial siderosis of the central nervous system. A report on nine cases with autopsy. Acta Neuropathol. 1969;13(1):56–74. doi: 10.1007/BF00686141. [DOI] [PubMed] [Google Scholar]
  4. Koeppen A. H., Barron K. D. Superficial siderosis of the central nervous system. A histological, histochemical and chemical study. J Neuropathol Exp Neurol. 1971 Jul;30(3):448–469. doi: 10.1097/00005072-197107000-00010. [DOI] [PubMed] [Google Scholar]
  5. Koeppen A. H., Dentinger M. P. Brain hemosiderin and superficial siderosis of the central nervous system. J Neuropathol Exp Neurol. 1988 May;47(3):249–270. doi: 10.1097/00005072-198805000-00005. [DOI] [PubMed] [Google Scholar]
  6. Ommaya A. K., Gennarelli T. A. Cerebral concussion and traumatic unconsciousness. Correlation of experimental and clinical observations of blunt head injuries. Brain. 1974 Dec;97(4):633–654. doi: 10.1093/brain/97.1.633. [DOI] [PubMed] [Google Scholar]
  7. TOMLINSON B. E., WALTON J. N. SUPERFICIAL HAEMOSIDEROSIS OF THE CENTRAL NERVOUS SYSTEM. J Neurol Neurosurg Psychiatry. 1964 Aug;27:332–339. doi: 10.1136/jnnp.27.4.332. [DOI] [PMC free article] [PubMed] [Google Scholar]