Factors Affecting the Distribution of Cytoplasmic Incompatibility in Drosophila Simulans (original) (raw)

Abstract

In Drosophila simulans a Wolbachia-like microorganism is responsible for reduced egg-hatch when infected males mate with uninfected females. Both incompatibility types have previously been found in North America, Europe and Africa. Some California populations have remained polymorphic for over two years, and the infection is apparently spreading in central California. Egg hatch proportions for wild-caught females from polymorphic populations show that the incompatibility system acts in nature, but egg mortality rates are apparently lower than observed in laboratory populations. Although infected females maintained under various laboratory conditions never produce uninfected offspring, some wild-caught infected females produce both infected and uninfected progeny. This helps explain the persistence of a low frequency of uninfected flies in predominantly infected populations and may also explain the other polymorphisms observed. Fitness comparisons of infected and uninfected stocks, including both larval and adult fitness components, indicate that fecundity may be the component most affected. Infected females suffer a fecundity reduction of 10-20% in the laboratory, but the reduction seems to be smaller in nature. A theoretical analysis provides some insight into the population biology of the infection.

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Selected References

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  1. Fine P. E. On the dynamics of symbiote-dependent cytoplasmic incompatibility in culicine mosquitoes. J Invertebr Pathol. 1978 Jan;31(1):10–18. doi: 10.1016/0022-2011(78)90102-7. [DOI] [PubMed] [Google Scholar]
  2. Hoffmann A. A., Turelli M. Unidirectional incompatibility in Drosophila simulans: inheritance, geographic variation and fitness effects. Genetics. 1988 Jun;119(2):435–444. doi: 10.1093/genetics/119.2.435. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Karlin S., McGregor J. Application of method of small parameters to multi-niche population genetic models. Theor Popul Biol. 1972 Jun;3(2):186–209. doi: 10.1016/0040-5809(72)90026-3. [DOI] [PubMed] [Google Scholar]
  4. Nigro L., Prout T. Is there selection on RFLP differences in mitochondrial DNA? Genetics. 1990 Jul;125(3):551–555. doi: 10.1093/genetics/125.3.551. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Skinner S. W. Son-killer: a third extrachromosomal factor affecting the sex ratio in the parasitoid wasp, Nasonia (=Mormoniella) vitripennis. Genetics. 1985 Apr;109(4):745–759. doi: 10.1093/genetics/109.4.745. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Stevens L. Environmental factors affecting reproductive incompatibility in flour beetles, genus Tribolium. J Invertebr Pathol. 1989 Jan;53(1):78–84. doi: 10.1016/0022-2011(89)90076-1. [DOI] [PubMed] [Google Scholar]