Crossover Suppressors and Balanced Recessive Lethals in CAENORHABDITIS ELEGANS (original) (raw)

Abstract

Two dominant suppressors of crossing over have been identified following X-ray treatment of the small nematode C. elegans. They suppress crossing over in linkage group II (LG_II_) about 100-fold and 50-fold and are both tightly linked to LG_II_ markers. One, called C1, segregates independently of all other linkage groups and is homozygous fertile. The other is a translocation involving LG_II_ and X. The translocation also suppresses crossing over along the right half of X and is homozygous lethal. C1 has been used as a balancer of LG_II_ recessive lethal and sterile mutations induced by EMS. The frequencies of occurrence of lethals and steriles were approximately equal. Fourteen mutations were assigned to complementation groups and mapped. They tended to map in the same region where LG_II_ visibles are clustered.

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Selected References

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