Genetic Analysis of Natural Populations of DROSOPHILA MELANOGASTER in Japan. IV. Natural Selection on the Inducibility, but Not on the Structural Genes, of Amylase Loci (original) (raw)

Abstract

To test the validity of previous results the inducibility of amylase as well as other biochemical parameters was measured using 45 homozygous strains of Drosophila melanogaster from Akayu, Japan. Only the inducibility (but not protein contents or specific activity of the enzyme) was highly correlated with productivity measured using a starch food regime (rp = 0.41, P < 0.005, rg = 0.73 ± 0.21). Inducibility was also negatively correlated with developmental time using starch food; namely, the one with high inducibility developed the fastest. Population cage experiments using 1600 genomes from the same natural population showed that the inducibility responded positively to natural selection (1.6-fold increase in inducibility in cages using starch food relative to those using normal food), but little frequency change of allozymes was observed. All of these results were consistent and indicated that polymorphisms of inducing factors or regulatory genes were major determinants of fitness differences in a particular environment and may be the genetic materials responsible for the adaptive evolution of organisms, at least in amylase loci.

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Selected References

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  1. Ayala F. J., Powell J. R., Dobzhansky T. Polymorphisms in continental and island populations of Drosophila willistoni. Proc Natl Acad Sci U S A. 1971 Oct;68(10):2480–2483. doi: 10.1073/pnas.68.10.2480. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. De Jong G., Scharloo W. Environmental determination of selective significance or neutrality of amylase variants in Drosophila melanogaster. Genetics. 1976 Sep;84(1):77–94. doi: 10.1093/genetics/84.1.77. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Jinks L. J., Connolly V. Determination of the environmental sensitivity of selection lines by the selection environment. Heredity (Edinb) 1975 Jun;34(3):401–406. doi: 10.1038/hdy.1975.49. [DOI] [PubMed] [Google Scholar]
  4. Muki T., Watanabe T. K., Yamaguchi O. The genetic structure of natural populations of Drosophila melanogaster. XII. Linkage disequilibrium in a large local population. Genetics. 1974 Aug;77(4):771–793. doi: 10.1093/genetics/77.4.771. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Powell J. R., Andjelković M. Population genetics of Drosophila amylase. IV. Selection in laboratory populations maintained on different carbohydrates. Genetics. 1983 Apr;103(4):675–689. doi: 10.1093/genetics/103.4.675. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Schaffer H. E., Yardley D., Anderson W. W. Drift or Selection: A Statistical Test of Gene Frequency Variation over Generations. Genetics. 1977 Oct;87(2):371–379. doi: 10.1093/genetics/87.2.371. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Wilson S. R. Analyzing gene-frequency data when the effective population size is finite. Genetics. 1980 Jun;95(2):489–502. doi: 10.1093/genetics/95.2.489. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Yamazaki T., Hirose Y. Genetic Analysis of Natural Populations of DROSOPHILA MELANOGASTER in Japan. II. the Measurement of Fitness and Fitness Components in Homozygous Lines. Genetics. 1984 Sep;108(1):213–221. doi: 10.1093/genetics/108.1.213. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Yamazaki T., Hirose Y. Genetic Analysis of Natural Populations of DROSOPHILA MELANOGASTER in Japan. II. the Measurement of Fitness and Fitness Components in Homozygous Lines. Genetics. 1984 Sep;108(1):213–221. doi: 10.1093/genetics/108.1.213. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Yamazaki T., Kusakabe S., Tachida H., Ichinose M., Yoshimaru H., Matsuo Y., Mukai T. Reexamination of diversifying selection of polymorphic allozyme genes by using population cages in Drosophila melanogaster. Proc Natl Acad Sci U S A. 1983 Sep;80(18):5789–5792. doi: 10.1073/pnas.80.18.5789. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Yamazaki T. Measurement of Fitness and Its Components in Six Laboratory Strains of DROSOPHILA MELANOGASTER. Genetics. 1984 Sep;108(1):201–211. doi: 10.1093/genetics/108.1.201. [DOI] [PMC free article] [PubMed] [Google Scholar]