On immunosurveillance in human cancer. (original) (raw)

Yale J Biol Med. 1982 May-Aug; 55(3-4): 329–333.

Abstract

The extraordinarily high incidence of cancers of many different varieties--carcinomas and lymphomas--in organ-transplant patients being maintained for long periods of time with immunosuppressive drugs is briefly reviewed. The role of immunosurveillance as a primary defense mechanism against cancer in human beings is consistent with these observations and is in need of further investigation. Conceivably, this mechanism may play a somewhat different role in humans from what has been observed in most experimental animal models.

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