Phagocytosis and Killing of Francisella tularensis by Human Polymorphonuclear Leukocytes (original) (raw)

Abstract

Bacteria of a wild strain of Francisella tularensis were less efficiently killed by human polymorphonuclear leukocytes than were bacteria of an attenuated strain. This finding was explained to some extent by a less efficient phagocytosis, but bacteria of the wild strain also seemed to be more resistant to killing after ingestion.

715

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Anderson S. E., Jr, Bautista S. C., Remington J. S. Specific antibody-dependent killing of Toxoplasma gondii by normal macrophages. Clin Exp Immunol. 1976 Dec;26(3):375–380. [PMC free article] [PubMed] [Google Scholar]
  2. CARLISLE H. N., HINCHLIFFE V., SASLAW S. Immunodiffusion studies with Pasteurella tularensis antigen-rabbit antibody systems. J Immunol. 1962 Nov;89:638–644. [PubMed] [Google Scholar]
  3. Canonico P. G., McManus A. T., Mangiafico J. A., Sammons L. S., McGann V. G., Dangerfield H. G. Temporal appearance of opsonizing antibody to Francisella tularensis: detection by a radiometabolic assay. Infect Immun. 1975 Mar;11(3):466–469. doi: 10.1128/iai.11.3.466-469.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Claflin J. L., Larson C. L. Infection-immunity in tularemia: specificity of cellular immunity. Infect Immun. 1972 Mar;5(3):311–318. doi: 10.1128/iai.5.3.311-318.1972. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. DIOGUARDI N., AGOSTONI A., FIORELLI G., LOMANTO B. Characterization of lactic dehydrogenase of normal human granulocytes. J Lab Clin Med. 1963 May;61:713–723. [PubMed] [Google Scholar]
  6. EIGELSBACH H. T., DOWNS C. M. Prophylactic effectiveness of live and killed tularemia vaccines. I. Production of vaccine and evaluation in the white mouse and guinea pig. J Immunol. 1961 Oct;87:415–425. [PubMed] [Google Scholar]
  7. Horwitz M. A., Silverstein S. C. Interaction of the Legionnaires' disease bacterium (Legionella pneumophila) with human phagocytes. I. L. pneumophila resists killing by polymorphonuclear leukocytes, antibody, and complement. J Exp Med. 1981 Feb 1;153(2):386–397. doi: 10.1084/jem.153.2.386. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Issekutz A. C., Lee K. Y., Biggar W. D. Enhancement of human neutrophil bactericidal activity by chemotactic factors. Infect Immun. 1979 May;24(2):295–301. doi: 10.1128/iai.24.2.295-301.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Kostiala A. A., McGregor D. D., Logie P. S. Tularaemia in the rat. I. The cellular basis on host resistance to infection. Immunology. 1975 May;28(5):855–869. [PMC free article] [PubMed] [Google Scholar]
  10. Kreutzer D. L., Dreyfus L. A., Robertson D. C. Interaction of polymorphonuclear leukocytes with smooth and rough strains of Brucella abortus. Infect Immun. 1979 Mar;23(3):737–742. doi: 10.1128/iai.23.3.737-742.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Löfgren S., Tärnvik A., Carlsson J. Demonstration of opsonizing antibodies to Francisella tularensis by leukocyte chemiluminescence. Infect Immun. 1980 Aug;29(2):329–334. doi: 10.1128/iai.29.2.329-334.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Löfgren S., Tärnvik A., Carlsson J. Influence of complement on the chemiluminescent response of human leukocytes to immune complex. Infect Immun. 1980 Aug;29(2):335–341. doi: 10.1128/iai.29.2.335-341.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Nutter J. E., Myrvik Q. N. In vitro interactions between rabbit alveolar macrophages and Pasteurella tularensis. J Bacteriol. 1966 Sep;92(3):645–651. doi: 10.1128/jb.92.3.645-651.1966. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. PANNELL L., DOWNS C. M. Studies on the pathogenesis and immunity of tularemia. I. The demonstration of a protective antibody in mouse serum. J Infect Dis. 1953 Mar-Apr;92(2):195–204. doi: 10.1093/infdis/92.2.195. [DOI] [PubMed] [Google Scholar]
  15. Patrone F., Dallegri F., Bonvini E., Sacchetti C. In vitro effects of synthetic chemotactic peptides on neutrophil function. Int Arch Allergy Appl Immunol. 1980;62(3):316–323. doi: 10.1159/000232528. [DOI] [PubMed] [Google Scholar]
  16. Proctor R. A., White J. D., Ayala E., Canonico P. G. Phagocytosis of Francisella tularensis by Rhesus monkey peripheral leukocytes. Infect Immun. 1975 Jan;11(1):146–151. doi: 10.1128/iai.11.1.146-151.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. SKOOG W. A., BECK W. S. Studies on the fibrinogen, dextran and phytohemagglutinin methods of isolating leukocytes. Blood. 1956 May;11(5):436–454. [PubMed] [Google Scholar]
  18. THORPE B. D., MARCUS S. PHAGOCYTOSIS AND INTRACELLULAR FATE OF PASTEURELLA TULARENSIS. 3. IN VIVO STUDIES WITH PASSIVELY TRANSFERRED CELLS AND SERA. J Immunol. 1965 Apr;94:578–585. [PubMed] [Google Scholar]
  19. Van Epps D. E., Garcia M. L. Enhancement of neutrophils function as a result of prior exposure to chemotactic factor. J Clin Invest. 1980 Aug;66(2):167–175. doi: 10.1172/JCI109841. [DOI] [PMC free article] [PubMed] [Google Scholar]