Anti-inflammatory and antioxidant properties of Helichrysum italicum - PubMed (original) (raw)
Anti-inflammatory and antioxidant properties of Helichrysum italicum
Araceli Sala et al. J Pharm Pharmacol. 2002 Mar.
Abstract
The anti-inflammatory and antioxidant activities of the aerial part of Helichrysum italicum extracts have been established in various in-vivo and in-vitro experimental models. The results obtained on the acute oedemas induced by 12-O-tetradecanoylphorbol 13-acetate (TPA) and ethyl phenylpropiolate in the mouse ear, by serotonin and phospholipase A2 (PLA2) in the mouse paw, on chronic inflammation induced by repeated application of TPA in the mouse ear and on the delayed-type hypersensitivity induced by sheep red blood cells suggest that said anti-inflammatory activity is due to the effects of compounds expressed via a corticoid-like mechanism. In addition, the antioxidant activity of the extracts seems to be implicated in this anti-inflammatory activity, as the former inhibits enzymatic and non-enzymatic lipid peroxidation and has free-radical scavenger properties. We conclude that the anti-inflammatory activity of Helichrysum italicum can be explained by multiple effects, including inflammatory enzyme inhibition, free-radical scavenging activity and corticoid-like effects.
Similar articles
- Helichrysum italicum: From Extraction, Distillation, and Encapsulation Techniques to Beneficial Health Effects.
Furlan V, Bren U. Furlan V, et al. Foods. 2023 Feb 13;12(4):802. doi: 10.3390/foods12040802. Foods. 2023. PMID: 36832877 Free PMC article. Review. - Assessment of the anti-inflammatory activity and free radical scavenger activity of tiliroside.
Sala A, Recio MC, Schinella GR, Máñez S, Giner RM, Cerdá-Nicolás M, Rosí JL. Sala A, et al. Eur J Pharmacol. 2003 Feb 7;461(1):53-61. doi: 10.1016/s0014-2999(02)02953-9. Eur J Pharmacol. 2003. PMID: 12568916 - A new dual inhibitor of arachidonate metabolism isolated from Helichrysum italicum.
Sala A, Recio MC, Schinella GR, Máñez S, Giner RM, Ríos JL. Sala A, et al. Eur J Pharmacol. 2003 Jan 24;460(2-3):219-26. doi: 10.1016/s0014-2999(02)02954-0. Eur J Pharmacol. 2003. PMID: 12559384 - In-vitro and in-vivo anti-inflammatory effect of oxyresveratrol from Morus alba L.
Chung KO, Kim BY, Lee MH, Kim YR, Chung HY, Park JH, Moon JO. Chung KO, et al. J Pharm Pharmacol. 2003 Dec;55(12):1695-700. doi: 10.1211/0022357022313. J Pharm Pharmacol. 2003. PMID: 14738598 - Helichrysum italicum: from traditional use to scientific data.
Antunes Viegas D, Palmeira-de-Oliveira A, Salgueiro L, Martinez-de-Oliveira J, Palmeira-de-Oliveira R. Antunes Viegas D, et al. J Ethnopharmacol. 2014;151(1):54-65. doi: 10.1016/j.jep.2013.11.005. Epub 2013 Nov 14. J Ethnopharmacol. 2014. PMID: 24239849 Review.
Cited by
- Bioassay-Guided Assessment of Antioxidative, Anti-Inflammatory and Antimicrobial Activities of Extracts from Medicinal Plants via High-Performance Thin-Layer Chromatography.
Jović MD, Agatonovic-Kustrin S, Ristivojević PM, Trifković JĐ, Morton DW. Jović MD, et al. Molecules. 2023 Oct 30;28(21):7346. doi: 10.3390/molecules28217346. Molecules. 2023. PMID: 37959765 Free PMC article. - HPLC Analysis and In Vitro and In Silico Evaluation of the Biological Activity of Polyphenolic Components Separated with Solvents of Various Polarities from Helichrysum italicum.
Bojilov D, Manolov S, Ahmed S, Dagnon S, Ivanov I, Marc G, Oniga S, Oniga O, Nedialkov P, Mollova S. Bojilov D, et al. Molecules. 2023 Aug 23;28(17):6198. doi: 10.3390/molecules28176198. Molecules. 2023. PMID: 37687028 Free PMC article. - Helichrysum italicum: From Extraction, Distillation, and Encapsulation Techniques to Beneficial Health Effects.
Furlan V, Bren U. Furlan V, et al. Foods. 2023 Feb 13;12(4):802. doi: 10.3390/foods12040802. Foods. 2023. PMID: 36832877 Free PMC article. Review. - Wound Healing and Anti-Inflammatory Effects of a Newly Developed Ointment Containing Jujube Leaves Extract.
Hovaneț MV, Ozon EA, Moroșan E, Șeremet OC, Oprea E, Geană EI, Anghel AI, Bădiceanu C, Duțu LE, Stoicescu CS, Nagoda E, Ancuceanu R. Hovaneț MV, et al. Life (Basel). 2022 Nov 22;12(12):1947. doi: 10.3390/life12121947. Life (Basel). 2022. PMID: 36556312 Free PMC article. - Antioxidant and Antibacterial Activity of Helichrysum italicum (Roth) G. Don. from Central Europe.
Węglarz Z, Kosakowska O, Pióro-Jabrucka E, Przybył JL, Gniewosz M, Kraśniewska K, Szyndel MS, Costa R, Bączek KB. Węglarz Z, et al. Pharmaceuticals (Basel). 2022 Jun 10;15(6):735. doi: 10.3390/ph15060735. Pharmaceuticals (Basel). 2022. PMID: 35745654 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical