Id proteins in cell growth and tumorigenesis - PubMed (original) (raw)
Review
Id proteins in cell growth and tumorigenesis
Hashmat A Sikder et al. Cancer Cell. 2003 Jun.
Free article
Abstract
Since the gene encoding Id1 was cloned in 1990, Id proteins have been implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. The development of knockout and transgenic animal models for many members of the Id gene family has been particularly useful in sorting out the biologic relevance of these genes and their expression during normal development, malignant transformation, and tumor progression. Here we review the current understanding of Id gene function, the biologic consequences of Id gene expression, and the implications for Id gene regulation of cell growth and tumorigenesis.
Similar articles
- ID helix-loop-helix proteins in cell growth, differentiation and tumorigenesis.
Norton JD. Norton JD. J Cell Sci. 2000 Nov;113 ( Pt 22):3897-905. doi: 10.1242/jcs.113.22.3897. J Cell Sci. 2000. PMID: 11058077 Review. - Expression of Id helix-loop-helix proteins in colorectal adenocarcinoma correlates with p53 expression and mitotic index.
Wilson JW, Deed RW, Inoue T, Balzi M, Becciolini A, Faraoni P, Potten CS, Norton JD. Wilson JW, et al. Cancer Res. 2001 Dec 15;61(24):8803-10. Cancer Res. 2001. PMID: 11751402 - Id proteins in cell cycle control and cellular senescence.
Zebedee Z, Hara E. Zebedee Z, et al. Oncogene. 2001 Dec 20;20(58):8317-25. doi: 10.1038/sj.onc.1205092. Oncogene. 2001. PMID: 11840324 Review. - Id proteins in development, cell cycle and cancer.
Ruzinova MB, Benezra R. Ruzinova MB, et al. Trends Cell Biol. 2003 Aug;13(8):410-8. doi: 10.1016/s0962-8924(03)00147-8. Trends Cell Biol. 2003. PMID: 12888293 Review. - Id-1 expression and cell survival.
Wong YC, Wang X, Ling MT. Wong YC, et al. Apoptosis. 2004 May;9(3):279-89. doi: 10.1023/b:appt.0000025804.25396.79. Apoptosis. 2004. PMID: 15258459 Review.
Cited by
- Id2 and Id3 define the potency of cell proliferation and differentiation responses to transforming growth factor beta and bone morphogenetic protein.
Kowanetz M, Valcourt U, Bergström R, Heldin CH, Moustakas A. Kowanetz M, et al. Mol Cell Biol. 2004 May;24(10):4241-54. doi: 10.1128/MCB.24.10.4241-4254.2004. Mol Cell Biol. 2004. PMID: 15121845 Free PMC article. - Nicotine-mediated invasion and migration of non-small cell lung carcinoma cells by modulating STMN3 and GSPT1 genes in an ID1-dependent manner.
Nair S, Bora-Singhal N, Perumal D, Chellappan S. Nair S, et al. Mol Cancer. 2014 Jul 16;13:173. doi: 10.1186/1476-4598-13-173. Mol Cancer. 2014. PMID: 25028095 Free PMC article. - Id1 Promotes Obesity by Suppressing Brown Adipose Thermogenesis and White Adipose Browning.
Patil M, Sharma BK, Elattar S, Chang J, Kapil S, Yuan J, Satyanarayana A. Patil M, et al. Diabetes. 2017 Jun;66(6):1611-1625. doi: 10.2337/db16-1079. Epub 2017 Mar 7. Diabetes. 2017. PMID: 28270523 Free PMC article. - Prostate cancer cells modulate osteoblast mineralisation and osteoclast differentiation through Id-1.
Yuen HF, Chiu YT, Chan KK, Chan YP, Chua CW, McCrudden CM, Tang KH, El-Tanani M, Wong YC, Wang X, Chan KW. Yuen HF, et al. Br J Cancer. 2010 Jan 19;102(2):332-41. doi: 10.1038/sj.bjc.6605480. Epub 2009 Dec 15. Br J Cancer. 2010. PMID: 20010941 Free PMC article. - Id2 promotes tumor cell migration and invasion through transcriptional repression of semaphorin 3F.
Coma S, Amin DN, Shimizu A, Lasorella A, Iavarone A, Klagsbrun M. Coma S, et al. Cancer Res. 2010 May 1;70(9):3823-32. doi: 10.1158/0008-5472.CAN-09-3048. Epub 2010 Apr 13. Cancer Res. 2010. PMID: 20388805 Free PMC article.