Natural history and pathophysiology of Q fever - PubMed (original) (raw)
Review
Natural history and pathophysiology of Q fever
D Raoult et al. Lancet Infect Dis. 2005 Apr.
Abstract
Q fever is a zoonosis caused by Coxiella burnetii. Infection with C burnetii can be acute or chronic, and exhibits a wide spectrum of clinical manifestations. The extreme infectivity of the bacterium results in large outbreaks and makes it a potential bioweapon. In the past decade, the complete genome sequencing of C burnetii, the exploration of bacterial interactions with the host, and the description of the natural history of the disease in human beings and in experimental models have all added to our knowledge about this fascinating disease. Advances in understanding the pathophysiology and natural history of Q fever are reviewed.
Comment in
- Q fever-related cholecystitis: a missed entity?
Reina-Serrano S, Jiménez-Sáenz M, Herrerías-Gutiérrez JM, Venero-Gómez J. Reina-Serrano S, et al. Lancet Infect Dis. 2005 Dec;5(12):734-5. doi: 10.1016/S1473-3099(05)70274-7. Lancet Infect Dis. 2005. PMID: 16310141 No abstract available.
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