A novel flavonoid from Lespedeza virgata (Thunb.) DC.: structural elucidation and antioxidative activity - PubMed (original) (raw)
. 2007 Nov 15;17(22):6311-5.
doi: 10.1016/j.bmcl.2007.09.003. Epub 2007 Sep 7.
Affiliations
- PMID: 17890083
- DOI: 10.1016/j.bmcl.2007.09.003
A novel flavonoid from Lespedeza virgata (Thunb.) DC.: structural elucidation and antioxidative activity
Li Tan et al. Bioorg Med Chem Lett. 2007.
Abstract
Bioactivity guided fractionation of the ethanolic extract of the whole plants of Lespedeza virgata (Thunb.) DC. resulted in the isolation of a novel flavonoid (1) along with five known compounds 2-6. The molecular and structural formula as well as the stereochemistry of compound 1 were determined using data obtained from (1)H and (13)C NMR spectra, DEPT135 and by 2D HSQC, HMBC, (1)H-(1)H correlated spectroscopy ((1)H-(1)H COSY), and nuclear overhauser effect spectroscopy (NOESY) experiments. The superoxide anion scavenging activities of all isolated compounds were evaluated by the hypoxanthine nitro blue tetrazolium and ESR methods and the new compound 1 showed the strongest antioxidative activity 95.79% (IC(50)=0.14 mg/ml).
Similar articles
- Antioxidant 2-phenylbenzofurans and a coumestan from Lespedeza virgata.
Chen Y, Wei X, Xie H, Deng H. Chen Y, et al. J Nat Prod. 2008 Jun;71(6):929-32. doi: 10.1021/np800016e. Epub 2008 May 17. J Nat Prod. 2008. PMID: 18484774 - Melanin synthesis inhibitors from Lespedeza floribunda.
Mori-Hongo M, Takimoto H, Katagiri T, Kimura M, Ikeda Y, Miyase T. Mori-Hongo M, et al. J Nat Prod. 2009 Feb 27;72(2):194-203. doi: 10.1021/np800395j. J Nat Prod. 2009. PMID: 19132934 - Melanin synthesis inhibitors from Lespedeza cyrtobotrya.
Mori-Hongo M, Yamaguchi H, Warashina T, Miyase T. Mori-Hongo M, et al. J Nat Prod. 2009 Jan;72(1):63-71. doi: 10.1021/np800535g. J Nat Prod. 2009. PMID: 19102656 - [Contents of flavonoids in the extract of Lespedeza virgata].
Chen Y, Deng HZ, Liang L. Chen Y, et al. Nan Fang Yi Ke Da Xue Xue Bao. 2008 May;28(5):858-60. Nan Fang Yi Ke Da Xue Xue Bao. 2008. PMID: 18504220 Chinese. - Structural determination of 3beta-stearyloxy-urs-12-ene from Maytenus salicifolia by 1D and 2D NMR and quantitative 13C NMR spectroscopy.
Miranda RR, Silva GD, Duarte LP, Fortes IC, Filho SA. Miranda RR, et al. Magn Reson Chem. 2006 Feb;44(2):127-31. doi: 10.1002/mrc.1734. Magn Reson Chem. 2006. PMID: 16358293
Cited by
- Flavonoids from Piper Species as Promising Antiprotozoal Agents against Giardia intestinalis. Structure-Activity Relationship and Drug-Likeness Studies.
Ticona JC, Bilbao-Ramos P, Amesty Á, Flores N, Dea-Ayuela MA, Bazzocchi IL, Jiménez IA. Ticona JC, et al. Pharmaceuticals (Basel). 2022 Nov 10;15(11):1386. doi: 10.3390/ph15111386. Pharmaceuticals (Basel). 2022. PMID: 36355559 Free PMC article. - High-Condensed Tannin Diet and Transportation Stress in Goats: Effects on Physiological Responses, Gut Microbial Counts and Meat Quality.
Batchu P, Hazard T, Lee JH, Terrill TH, Kouakou B, Kannan G. Batchu P, et al. Animals (Basel). 2021 Sep 30;11(10):2857. doi: 10.3390/ani11102857. Animals (Basel). 2021. PMID: 34679877 Free PMC article. - A potential anti-inflammation activity and depigmentation effect of Lespedeza bicolor extract and its fractions.
Lee SJ, Hossaine MD, Park SC. Lee SJ, et al. Saudi J Biol Sci. 2016 Jan;23(1):9-14. doi: 10.1016/j.sjbs.2015.01.016. Epub 2015 Feb 9. Saudi J Biol Sci. 2016. PMID: 26858533 Free PMC article. - Phytochemical and Biological Investigation of Two Diplotaxis Species Growing in Tunisia: D. virgata & D. erucoides.
Salah NB, Casabianca H, Jannet HB, Chenavas S, Sanglar C, Fildier A, Bouzouita N. Salah NB, et al. Molecules. 2015 Oct 5;20(10):18128-43. doi: 10.3390/molecules201018128. Molecules. 2015. PMID: 26445040 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
Miscellaneous