Cancer prevention by carotenoids - PubMed (original) (raw)
Review
. 2009 Mar 15;483(2):165-8.
doi: 10.1016/j.abb.2008.09.011. Epub 2008 Sep 30.
Affiliations
- PMID: 18848517
- DOI: 10.1016/j.abb.2008.09.011
Review
Cancer prevention by carotenoids
Hoyoku Nishino et al. Arch Biochem Biophys. 2009.
Abstract
Various natural carotenoids seem to be valuable for cancer prevention, and these carotenoids may be more suitable in combinational use, rather than in single use. In fact, we have proven that combinational use of natural carotenoids resulted in significant suppression of liver cancer. Patients of viral hepatitis with cirrhosis were administered with beta-cryptoxanthin-enriched Mandarin orange juice, in addition to capsules of carotenoids mixture. Cumulative incidence of hepatocellular carcinoma development was compared with that in the group treated with carotenoids mixture capsules alone, or in the group without treatment (control group). In the data analysis at year 2.5, cumulative incidence of liver cancer in beta-cryptoxanthin-enriched orange juice with carotenoids mixture capsules-treated group was lower than that in the control group (p=0.05). Cumulative incidence of liver cancer in the group treated with carotenoids mixture capsules alone was also lower than that in the control group, but not statistically significant.
Similar articles
- Cancer prevention by natural carotenoids.
Nishino H. Nishino H. J Cell Biochem Suppl. 1997;27:86-91. J Cell Biochem Suppl. 1997. PMID: 9591197 - [The immunological role of carotenoids in the prevention of cancer].
Tomita Y, Fukuda K, Hirohata T. Tomita Y, et al. Gan No Rinsho. 1986 May;32(6):643-51. Gan No Rinsho. 1986. PMID: 3489110 Japanese. - Interferon therapy in chronic hepatitis B reduces progression to cirrhosis and hepatocellular carcinoma: a meta-analysis.
Yang YF, Zhao W, Zhong YD, Xia HM, Shen L, Zhang N. Yang YF, et al. J Viral Hepat. 2009 Apr;16(4):265-71. doi: 10.1111/j.1365-2893.2009.01070.x. Epub 2009 Feb 12. J Viral Hepat. 2009. PMID: 19220736 - Influence of observational study design on the interpretation of cancer risk reduction by carotenoids.
Musa-Veloso K, Card JW, Wong AW, Cooper DA. Musa-Veloso K, et al. Nutr Rev. 2009 Sep;67(9):527-45. doi: 10.1111/j.1753-4887.2009.00225.x. Nutr Rev. 2009. PMID: 19703260 Review. - Carotenoids: actual knowledge on food sources, intakes, stability and bioavailability and their protective role in humans.
Maiani G, Castón MJ, Catasta G, Toti E, Cambrodón IG, Bysted A, Granado-Lorencio F, Olmedilla-Alonso B, Knuthsen P, Valoti M, Böhm V, Mayer-Miebach E, Behsnilian D, Schlemmer U. Maiani G, et al. Mol Nutr Food Res. 2009 Sep;53 Suppl 2:S194-218. doi: 10.1002/mnfr.200800053. Mol Nutr Food Res. 2009. PMID: 19035552 Review.
Cited by
- Biochemical Characterization of New Sweet Orange Mutants Rich in Lycopene and β-Carotene Antioxidants.
Carmona L, Alquézar B, Peña L. Carmona L, et al. Antioxidants (Basel). 2024 Aug 16;13(8):994. doi: 10.3390/antiox13080994. Antioxidants (Basel). 2024. PMID: 39199239 Free PMC article. - Preventive Effects of Fucoidan and Fucoxanthin on Hyperuricemic Rats Induced by Potassium Oxonate.
Chau YT, Chen HY, Lin PH, Hsia SM. Chau YT, et al. Mar Drugs. 2019 Jun 10;17(6):343. doi: 10.3390/md17060343. Mar Drugs. 2019. PMID: 31185695 Free PMC article. - Fucoxanthin Prevents Pancreatic Tumorigenesis in C57BL/6J Mice That Received Allogenic and Orthotopic Transplants of Cancer Cells.
Murase W, Kamakura Y, Kawakami S, Yasuda A, Wagatsuma M, Kubota A, Kojima H, Ohta T, Takahashi M, Mutoh M, Tanaka T, Maeda H, Miyashita K, Terasaki M. Murase W, et al. Int J Mol Sci. 2021 Dec 19;22(24):13620. doi: 10.3390/ijms222413620. Int J Mol Sci. 2021. PMID: 34948416 Free PMC article. - In Vitro Anticancer Activity of Staphyloxanthin Pigment Extracted from Staphylococcus gallinarum KX912244, a Gut Microbe of Bombyx mori.
Barretto DA, Vootla SK. Barretto DA, et al. Indian J Microbiol. 2018 Jun;58(2):146-158. doi: 10.1007/s12088-018-0718-0. Epub 2018 Mar 16. Indian J Microbiol. 2018. PMID: 29651173 Free PMC article. - Absorption, metabolism, and functions of β-cryptoxanthin.
Burri BJ, La Frano MR, Zhu C. Burri BJ, et al. Nutr Rev. 2016 Feb;74(2):69-82. doi: 10.1093/nutrit/nuv064. Epub 2016 Jan 7. Nutr Rev. 2016. PMID: 26747887 Free PMC article. Review.