In vitro activity of essential oils extracted from plants used as spices against fluconazole-resistant and fluconazole-susceptible Candida spp - PubMed (original) (raw)
In vitro activity of essential oils extracted from plants used as spices against fluconazole-resistant and fluconazole-susceptible Candida spp
Patrícia Pozzatti et al. Can J Microbiol. 2008 Nov.
Abstract
In the present study, the antifungal activity of selected essential oils obtained from plants used as spices was evaluated against both fluconazole-resistant and fluconazole-susceptible Candida spp. The Candida species studied were Candida albicans, Candida dubliniensis, Candida tropicalis, Candida glabrata, and Candida krusei. For comparison purposes, they were arranged in groups as C. albicans, C. dubliniensis, and Candida non-albicans. The essential oils were obtained from Cinnamomum zeylanicum Breyn, Lippia graveolens HBK, Ocimum basilicum L., Origanum vulgare L., Rosmarinus officinalis L., Salvia officinalis L., Thymus vulgaris L., and Zingiber officinale. The susceptibility tests were based on the M27-A2 methodology. The chemical composition of the essential oils was obtained by gas chromatography-mass spectroscopy and by retention indices. The results showed that cinnamon, Mexican oregano, oregano, thyme, and ginger essential oils have different levels of antifungal activity. Oregano and ginger essential oils were found to be the most and the least efficient, respectively. The main finding was that the susceptibilities of fluconazole-resistant C. albicans, C. dubliniensis, and Candida non-albicans to Mexican oregano, oregano, thyme, and ginger essential oils were higher than those of the fluconazole-susceptible yeasts (P<0.05). In contrast, fluconazole-resistant C. albicans and Candida non-albicans were less susceptible to cinnamon essential oil than their fluconazole-susceptible counterparts (P<0.05). A relationship between the yeasts' susceptibilities and the chemical composition of the essential oils studied was apparent when these 2 parameters were compared. Finally, basil, rosemary, and sage essential oils did not show antifungal activity against Candida isolates at the tested concentrations.
Similar articles
- In vitro activity of essential oils extracted from condiments against fluconazole-resistant and -sensitive Candida glabrata.
Soares IH, Loreto ÉS, Rossato L, Mario DN, Venturini TP, Baldissera F, Santurio JM, Alves SH. Soares IH, et al. J Mycol Med. 2015 Sep;25(3):213-7. doi: 10.1016/j.mycmed.2015.06.003. Epub 2015 Aug 14. J Mycol Med. 2015. PMID: 26281965 - Comparison of the susceptibilities of clinical isolates of Candida albicans and Candida dubliniensis to essential oils.
Pozzatti P, Loreto ES, Lopes PG, Athayde ML, Santurio JM, Alves SH. Pozzatti P, et al. Mycoses. 2010 Jan;53(1):12-5. doi: 10.1111/j.1439-0507.2008.01643.x. Epub 2009 Jan 14. Mycoses. 2010. PMID: 19207850 - Liquid and vapour-phase antifungal activities of essential oils against Candida albicans and non-albicans Candida.
Mandras N, Nostro A, Roana J, Scalas D, Banche G, Ghisetti V, Del Re S, Fucale G, Cuffini AM, Tullio V. Mandras N, et al. BMC Complement Altern Med. 2016 Aug 30;16(1):330. doi: 10.1186/s12906-016-1316-5. BMC Complement Altern Med. 2016. PMID: 27576581 Free PMC article. - Candida dubliniensis, a new fungal pathogen.
Gutiérrez J, Morales P, González MA, Quindós G. Gutiérrez J, et al. J Basic Microbiol. 2002;42(3):207-27. doi: 10.1002/1521-4028(200206)42:3<207::AID-JOBM207>3.0.CO;2-C. J Basic Microbiol. 2002. PMID: 12111748 Review. - Antimicrobial Activity of Basil, Oregano, and Thyme Essential Oils.
Sakkas H, Papadopoulou C. Sakkas H, et al. J Microbiol Biotechnol. 2017 Mar 28;27(3):429-438. doi: 10.4014/jmb.1608.08024. J Microbiol Biotechnol. 2017. PMID: 27994215 Review.
Cited by
- Antifungal Properties of Essential Oils and Their Compounds for Application in Skin Fungal Infections: Conventional and Nonconventional Approaches.
Abd Rashed A, Rathi DG, Ahmad Nasir NAH, Abd Rahman AZ. Abd Rashed A, et al. Molecules. 2021 Feb 19;26(4):1093. doi: 10.3390/molecules26041093. Molecules. 2021. PMID: 33669627 Free PMC article. Review. - Antifungal Activity of Novel Formulations Based on Terpenoid Prodrugs against C. albicans in a Mouse Model.
Menon S, Liang X, Vartak R, Patel K, Di Stefano A, Cacciatore I, Marinelli L, Billack B. Menon S, et al. Pharmaceutics. 2021 Apr 29;13(5):633. doi: 10.3390/pharmaceutics13050633. Pharmaceutics. 2021. PMID: 33946740 Free PMC article. - Chemical Constituents and Biologic Activities of Sage Species: A Comparison between Salvia officinalis L., S. glutinosa L. and S. transsylvanica (Schur ex Griseb. & Schenk) Schur.
Mocan A, Babota M, Pop A, Fizeșan I, Diuzheva A, Locatelli M, Carradori S, Campestre C, Menghini L, Sisea CR, Soković M, Zengin G, Păltinean R, Badarau S, C Vodnar DC, Crișan G. Mocan A, et al. Antioxidants (Basel). 2020 Jun 2;9(6):480. doi: 10.3390/antiox9060480. Antioxidants (Basel). 2020. PMID: 32498441 Free PMC article. - Antifungal Properties of Zataria multiflora on Candida species: A Systematic Review.
Shafaroudi AM, Gorji NE, Nasiri P, Javidnia J, Saravi ME. Shafaroudi AM, et al. J Evid Based Integr Med. 2022 Jan-Dec;27:2515690X221132272. doi: 10.1177/2515690X221132272. J Evid Based Integr Med. 2022. PMID: 36423242 Free PMC article. Review. - Control of Penicillium sp. on the Surface of Italian Salami Using Essential Oils.
Cenci AM, Ugalde ML, Steffens J, Valduga E, Cansian RL, Toniazzo G. Cenci AM, et al. Food Technol Biotechnol. 2015 Sep;53(3):342-347. doi: 10.17113/ftb.53.03.15.3877. Food Technol Biotechnol. 2015. PMID: 27904367 Free PMC article.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Miscellaneous