Clinical evidence for immunomodulatory effects of probiotic bacteria - PubMed (original) (raw)
Review
Clinical evidence for immunomodulatory effects of probiotic bacteria
F M Ruemmele et al. J Pediatr Gastroenterol Nutr. 2009 Feb.
Abstract
Close, tightly orchestrated interactions between the intestinal epithelium and the mucosa-associated immune system are critical for normal intestinal absorptive and immunological functions. Recent data indicate that commensal intestinal microbiota represents a major modulator of intestinal homeostasis. This review analyzes the process of intestinal colonization and the interaction of microbiota with the intestinal epithelium and mucosal immune system, with special reference to the first years of extrauterine life. Dysregulation of the symbiotic interaction between intestinal microbiota and the mucosa may result in a pathological condition with potential clinical repercussions. Based on the concept that there is a beneficial and symbiotic relation between the host and endogenous microbiota, strategies aimed at directly modulating intestinal microbiota with regard to disease prevention or treatment have been developed. One strategy involves administering viable probiotic bacteria. Clinical evidence for the beneficial effect of probiotics in the prevention and/or treatment of necrotizing enterocolitis, infectious and antibiotic-associated diarrhea, allergic diseases, and inflammatory bowel disorders is reviewed herein.
Similar articles
- Probiotics: use in allergic disorders: a Nutrition, Allergy, Mucosal Immunology, and Intestinal Microbiota (NAMI) Research Group Report.
Isolauri E, Salminen S; Nutrition, Allergy, Mucosal Immunology, and Intestinal Microbiota (NAMI) Research Group Report. Isolauri E, et al. J Clin Gastroenterol. 2008 Jul;42 Suppl 2:S91-6. doi: 10.1097/MCG.0b013e3181639a98. J Clin Gastroenterol. 2008. PMID: 18542035 Review. - The 'microflora hypothesis' of allergic diseases.
Noverr MC, Huffnagle GB. Noverr MC, et al. Clin Exp Allergy. 2005 Dec;35(12):1511-20. doi: 10.1111/j.1365-2222.2005.02379.x. Clin Exp Allergy. 2005. PMID: 16393316 Review. - Inflammatory bowel disease, gut bacteria and probiotic therapy.
Reiff C, Kelly D. Reiff C, et al. Int J Med Microbiol. 2010 Jan;300(1):25-33. doi: 10.1016/j.ijmm.2009.08.004. Epub 2009 Oct 2. Int J Med Microbiol. 2010. PMID: 19800289 Review. - Gut microbiota, probiotics and inflammatory bowel disease.
Stephani J, Radulovic K, Niess JH. Stephani J, et al. Arch Immunol Ther Exp (Warsz). 2011 Jun;59(3):161-77. doi: 10.1007/s00005-011-0122-5. Epub 2011 Mar 29. Arch Immunol Ther Exp (Warsz). 2011. PMID: 21445715 Review. - The long-term health effects of neonatal microbial flora.
Conroy ME, Shi HN, Walker WA. Conroy ME, et al. Curr Opin Allergy Clin Immunol. 2009 Jun;9(3):197-201. doi: 10.1097/ACI.0b013e32832b3f1d. Curr Opin Allergy Clin Immunol. 2009. PMID: 19398905 Review.
Cited by
- Oral probiotic administration attenuates postexercise inflammation in horses.
Jacobs RD, Grum D, Trible B, Ayala DI, Karnezos TP, Gordon ME. Jacobs RD, et al. Transl Anim Sci. 2024 Aug 13;8:txae124. doi: 10.1093/tas/txae124. eCollection 2024. Transl Anim Sci. 2024. PMID: 39281311 Free PMC article. - The Efficacy of Paraprobiotic Lozenges (Lactobacillus helveticus MIMLh5) for the Prevention of Acute and Chronic Nose and Throat Infections in Children.
Baljošević I, Šubarević V, Stanković K, Bajec Opančina A, Novković M, Petrovic M. Baljošević I, et al. Medicina (Kaunas). 2024 Jul 30;60(8):1235. doi: 10.3390/medicina60081235. Medicina (Kaunas). 2024. PMID: 39202516 Free PMC article. - The effects of probiotics, prebiotics, and synbiotics on polycystic ovarian syndrome: an overview of systematic reviews.
Angoorani P, Ejtahed HS, Ettehad Marvasti F, Taghavi M, Mohammadpour Ahranjani B, Hasani-Ranjbar S, Larijani B. Angoorani P, et al. Front Med (Lausanne). 2023 Jun 9;10:1141355. doi: 10.3389/fmed.2023.1141355. eCollection 2023. Front Med (Lausanne). 2023. PMID: 37359018 Free PMC article. - Effects of Microecological Regulators on Rheumatoid Arthritis: A Systematic Review and Meta-Analysis of Randomized, Controlled Trials.
Wu T, Li Y, Wu Y, Liang X, Zhou Y, Liao Z, Wen J, Cheng L, Luo Y, Liu Y. Wu T, et al. Nutrients. 2023 Feb 22;15(5):1102. doi: 10.3390/nu15051102. Nutrients. 2023. PMID: 36904103 Free PMC article. Review. - Nutritional approach for increasing public health during pandemic of COVID-19: A comprehensive review of antiviral nutrients and nutraceuticals.
Ebrahimzadeh-Attari V, Panahi G, Hebert JR, Ostadrahimi A, Saghafi-Asl M, Lotfi-Yaghin N, Baradaran B. Ebrahimzadeh-Attari V, et al. Health Promot Perspect. 2021 May 19;11(2):119-136. doi: 10.34172/hpp.2021.17. eCollection 2021. Health Promot Perspect. 2021. PMID: 34195036 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical