Dairy products and metabolic effects in overweight men and women: results from a 6-mo intervention study - PubMed (original) (raw)
Randomized Controlled Trial
doi: 10.3945/ajcn.2009.27664. Epub 2009 Aug 26.
Annika Smedman, Anu M Turpeinen, Kjetil Retterstøl, Siv Tengblad, Endla Lipre, Antti Aro, Pertti Mutanen, Ingebjørg Seljeflot, Samar Basu, Jan I Pedersen, Marja Mutanen, Bengt Vessby
Affiliations
- PMID: 19710195
- DOI: 10.3945/ajcn.2009.27664
Free article
Randomized Controlled Trial
Dairy products and metabolic effects in overweight men and women: results from a 6-mo intervention study
Marianne Hauge Wennersberg et al. Am J Clin Nutr. 2009 Oct.
Free article
Abstract
Background: Some epidemiologic studies have suggested inverse relations between intake of dairy products and components of the metabolic syndrome.
Objective: The objective was to investigate the effects of an increased intake of dairy products in persons with a habitually low intake on body composition and factors related to the metabolic syndrome.
Design: Middle-aged overweight subjects (n = 121) with traits of the metabolic syndrome were recruited in Finland, Norway, and Sweden and randomly assigned into milk or control groups. The milk group was instructed to consume 3-5 portions of dairy products daily. The control group maintained their habitual diet. Clinical investigations were conducted on admission and after 6 mo.
Results: There were no significant differences between changes in body weight or body composition, blood pressure, markers of inflammation, endothelial function, adiponectin, or oxidative stress in the milk and the control groups. There was a modest unfavorable increase in serum cholesterol concentrations in the milk group (P = 0.043). Among participants with a low calcium intake at baseline (<700 mg/d), there was a significant treatment effect for waist circumference (P = 0.003) and sagittal abdominal diameter (P = 0.034). When the sexes were analyzed separately, leptin increased (P = 0.045) and vascular cell adhesion molecule-1 decreased (P = 0.001) in women in the milk group.
Conclusions: This study gives no clear support to the hypothesis that a moderately increased intake of dairy products beneficially affects aspects of the metabolic syndrome. The apparently positive effects on waist circumference and sagittal abdominal diameter in subjects with a low calcium intake suggest a possible threshold in relation to effects on body composition.
Similar articles
- Dairy consumption and 6-y changes in body weight and waist circumference in middle-aged French adults.
Vergnaud AC, Péneau S, Chat-Yung S, Kesse E, Czernichow S, Galan P, Hercberg S, Bertrais S. Vergnaud AC, et al. Am J Clin Nutr. 2008 Nov;88(5):1248-55. doi: 10.3945/ajcn.2007.25151. Am J Clin Nutr. 2008. PMID: 18996859 - Effects of low-fat milk consumption on metabolic and atherogenic biomarkers in Korean adults with the metabolic syndrome: a randomised controlled trial.
Lee YJ, Seo JA, Yoon T, Seo I, Lee JH, Im D, Lee JH, Bahn KN, Ham HS, Jeong SA, Kang TS, Ahn JH, Kim DH, Nam GE, Kim NH. Lee YJ, et al. J Hum Nutr Diet. 2016 Aug;29(4):477-86. doi: 10.1111/jhn.12349. Epub 2016 Mar 6. J Hum Nutr Diet. 2016. PMID: 26945812 Clinical Trial. - Dairy product consumption, calcium intakes, and metabolic syndrome-related factors over 5 years in the STANISLAS study.
Samara A, Herbeth B, Ndiaye NC, Fumeron F, Billod S, Siest G, Visvikis-Siest S. Samara A, et al. Nutrition. 2013 Mar;29(3):519-24. doi: 10.1016/j.nut.2012.08.013. Epub 2012 Dec 28. Nutrition. 2013. PMID: 23274089 - Dairy product consumption and the metabolic syndrome.
van Meijl LE, Vrolix R, Mensink RP. van Meijl LE, et al. Nutr Res Rev. 2008 Dec;21(2):148-57. doi: 10.1017/S0954422408116997. Nutr Res Rev. 2008. PMID: 19087368 Review. - Yogurt and dairy product consumption to prevent cardiometabolic diseases: epidemiologic and experimental studies.
Astrup A. Astrup A. Am J Clin Nutr. 2014 May;99(5 Suppl):1235S-42S. doi: 10.3945/ajcn.113.073015. Epub 2014 Apr 2. Am J Clin Nutr. 2014. PMID: 24695891 Review.
Cited by
- Milk protein concentrate supplementation improved appetite, metabolic parameters, adipocytokines, and body composition in dieting women with obesity: a randomized controlled trial.
Elahikhah M, Haidari F, Khalesi S, Shahbazian H, Mohammadshahi M, Aghamohammadi V. Elahikhah M, et al. BMC Nutr. 2024 Jun 3;10(1):80. doi: 10.1186/s40795-024-00879-1. BMC Nutr. 2024. PMID: 38831442 Free PMC article. - Effects of Dairy Intake on Markers of Cardiometabolic Health in Adults: A Systematic Review with Network Meta-Analysis.
Kiesswetter E, Stadelmaier J, Petropoulou M, Morze J, Grummich K, Roux I, Lay R, Himmelsbach L, Kussmann M, Roeger C, Rubach M, Hauner H, Schwingshackl L. Kiesswetter E, et al. Adv Nutr. 2023 May;14(3):438-450. doi: 10.1016/j.advnut.2023.03.004. Epub 2023 Mar 11. Adv Nutr. 2023. PMID: 36914032 Free PMC article. Review. - Saturated fat from dairy sources is associated with lower cardiometabolic risk in the Framingham Offspring Study.
Yuan M, Singer MR, Pickering RT, Moore LL. Yuan M, et al. Am J Clin Nutr. 2022 Dec 19;116(6):1682-1692. doi: 10.1093/ajcn/nqac224. Am J Clin Nutr. 2022. PMID: 36307959 Free PMC article. - Association between dairy product intake and high blood pressure in Chilean adults.
Morejón-Terán Y, Pizarro R, Mauritz L, Díaz D, Durán Agüero S. Morejón-Terán Y, et al. J Prev Med Hyg. 2021 Sep 15;62(3):E681-E688. doi: 10.15167/2421-4248/jpmh2021.62.3.2077. eCollection 2021 Sep. J Prev Med Hyg. 2021. PMID: 34909496 Free PMC article. - Exploring the Links between Diet and Inflammation: Dairy Foods as Case Studies.
Hess JM, Stephensen CB, Kratz M, Bolling BW. Hess JM, et al. Adv Nutr. 2021 Oct 11;12(Suppl 1):1S-13S. doi: 10.1093/advances/nmab108. Adv Nutr. 2021. PMID: 34632478 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical