Consumption of cocoa flavanols results in acute improvements in mood and cognitive performance during sustained mental effort - PubMed (original) (raw)
Clinical Trial
. 2010 Oct;24(10):1505-14.
doi: 10.1177/0269881109106923. Epub 2009 Nov 26.
Affiliations
- PMID: 19942640
- DOI: 10.1177/0269881109106923
Clinical Trial
Consumption of cocoa flavanols results in acute improvements in mood and cognitive performance during sustained mental effort
Andrew B Scholey et al. J Psychopharmacol. 2010 Oct.
Abstract
Cocoa flavanols (CF) positively influence physiological processes in ways that suggest their consumption may improve aspects of cognitive function. This study investigated the acute cognitive and subjective effects of CF consumption during sustained mental demand. In this randomized, controlled, double-blinded, balanced, three period crossover trial 30 healthy adults consumed drinks containing 520 mg, 994 mg CF and a matched control, with a three-day washout between drinks. Assessments included the state anxiety inventory and repeated 10-min cycles of a Cognitive Demand Battery comprising of two serial subtraction tasks (Serial Threes and Serial Sevens), a Rapid Visual Information Processing (RVIP) task and a 'mental fatigue' scale, over the course of 1 h. Consumption of both 520 mg and 994 mg CF significantly improved Serial Threes performance. The 994 mg CF beverage significantly speeded RVIP responses but also resulted in more errors during Serial Sevens. Increases in self-reported 'mental fatigue' were significantly attenuated by the consumption of the 520 mg CF beverage only. This is the first report of acute cognitive improvements following CF consumption in healthy adults. While the mechanisms underlying the effects are unknown they may be related to known effects of CF on endothelial function and blood flow.
Similar articles
- Consumption of cocoa flavanols results in an acute improvement in visual and cognitive functions.
Field DT, Williams CM, Butler LT. Field DT, et al. Physiol Behav. 2011 Jun 1;103(3-4):255-60. doi: 10.1016/j.physbeh.2011.02.013. Epub 2011 Feb 12. Physiol Behav. 2011. PMID: 21324330 Clinical Trial. - Effects of Panax ginseng, consumed with and without glucose, on blood glucose levels and cognitive performance during sustained 'mentally demanding' tasks.
Reay JL, Kennedy DO, Scholey AB. Reay JL, et al. J Psychopharmacol. 2006 Nov;20(6):771-81. doi: 10.1177/0269881106061516. Epub 2006 Jan 9. J Psychopharmacol. 2006. PMID: 16401645 Clinical Trial. - Single doses of Panax ginseng (G115) reduce blood glucose levels and improve cognitive performance during sustained mental activity.
Reay JL, Kennedy DO, Scholey AB. Reay JL, et al. J Psychopharmacol. 2005 Jul;19(4):357-65. doi: 10.1177/0269881105053286. J Psychopharmacol. 2005. PMID: 15982990 Clinical Trial. - A glucose-caffeine 'energy drink' ameliorates subjective and performance deficits during prolonged cognitive demand.
Kennedy DO, Scholey AB. Kennedy DO, et al. Appetite. 2004 Jun;42(3):331-3. doi: 10.1016/j.appet.2004.03.001. Appetite. 2004. PMID: 15183925 Clinical Trial. - Neural mechanisms of mental fatigue.
Ishii A, Tanaka M, Watanabe Y. Ishii A, et al. Rev Neurosci. 2014;25(4):469-79. doi: 10.1515/revneuro-2014-0028. Rev Neurosci. 2014. PMID: 24926625 Review.
Cited by
- Cacao Ameliorates Amyloid Beta-Induced Cognitive and Non-Cognitive Disturbances.
Basir HS, Mirazi N, Komaki A, Ramezani M, Hosseini A. Basir HS, et al. Neurosci Insights. 2024 Sep 17;19:26331055241280638. doi: 10.1177/26331055241280638. eCollection 2024. Neurosci Insights. 2024. PMID: 39314637 Free PMC article. - Proceedings of the 2022 "Lifestyle Intervention for Epilepsy (LIFE)" symposium hosted by Cleveland Clinic.
Spurgeon E, Saper R, Alexopoulos A, Allendorfer JB, Bar J, Caldwell J, Cervenka M, Darling S, Dombrowski S, Gallagher L, Lazar S, Modlo E, Perko J, Sajatovic M, Tilahun B, Yardi N, Najm I. Spurgeon E, et al. Epilepsia Open. 2024 Oct;9(5):1981-1996. doi: 10.1002/epi4.13037. Epub 2024 Aug 23. Epilepsia Open. 2024. PMID: 39177045 Free PMC article. - Flavonoids as Potential Therapeutics Against Neurodegenerative Disorders: Unlocking the Prospects.
Faysal M, Dehbia Z, Zehravi M, Sweilam SH, Haque MA, Kumar KP, Chakole RD, Shelke SP, Sirikonda S, Nafady MH, Khan SL, Nainu F, Ahmad I, Emran TB. Faysal M, et al. Neurochem Res. 2024 Aug;49(8):1926-1944. doi: 10.1007/s11064-024-04177-x. Epub 2024 Jun 1. Neurochem Res. 2024. PMID: 38822985 Review. - Acute effects of mango leaf extract on cognitive function in healthy adults: a randomised, double-blind, placebo-controlled crossover study.
Dodd FL, Kennedy DO, Johnson J, Haworth E, Greener JP, Jackson PA. Dodd FL, et al. Front Nutr. 2024 Apr 11;11:1298807. doi: 10.3389/fnut.2024.1298807. eCollection 2024. Front Nutr. 2024. PMID: 38665302 Free PMC article. - Dietary Cocoa Flavanols Do Not Alter Brain Excitability in Young Healthy Adults.
Hamel R, Oyler R, Harms E, Bailey R, Rendeiro C, Jenkinson N. Hamel R, et al. Nutrients. 2024 Mar 27;16(7):969. doi: 10.3390/nu16070969. Nutrients. 2024. PMID: 38613003 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources